Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Reinhard Fritsch"'
Publikováno v:
WASSERWIRTSCHAFT. 105:32-35
Autor:
Rainer Schindl, Reinhard Fritsch, Maria Christine Riedl, David House, Isabella Derler, Peter Heftberger, Christoph Romanin, Malcolm Begg
Publikováno v:
Cell Calcium
As the molecular composition of calcium-release activated calcium (CRAC) channels has been unknown for two decades, elucidation of selective inhibitors has been considerably hampered. By the identification of the two key components of CRAC channels,
Autor:
Christoph Romanin, Judith Bergsmann, Marc Fahrner, Klaus Groschner, Isabella Derler, Irene Frischauf, Martin Muik, Barbara Lackner, Reinhard Fritsch, Rainer Schindl
Publikováno v:
The Journal of Biological Chemistry
Activation of immune cells is triggered by the Ca(2+) release-activated Ca(2+) current, which is mediated via channels of the Orai protein family. A key gating process of the three Orai channel isoforms to prevent Ca(2+) overload is fast inactivation
Publikováno v:
Expert Opinion on Drug Discovery. 3:787-800
Background: Ca2+ release-activated Ca2+ (CRAC) channels, a subfamily of store-operated channels, play an essential role in various diseases such as immune disorders and allergic responses. Objective: The successful treatment of these diseases require
Autor:
Christoph Romanin, Jean-Charles Hoda, Alexandra Koschak, Mathias Gebhart, Martina J. Sinnegger-Brauns, Jutta Engel, Chiara Poggiani, Reinhard Fritsch, Jörg Striessnig, Anamika Singh
Publikováno v:
The Journal of Biological Chemistry
Low voltage activation of Ca(V)1.3 L-type Ca(2+) channels controls excitability in sensory cells and central neurons as well as sinoatrial node pacemaking. Ca(V)1.3-mediated pacemaking determines neuronal vulnerability of dopaminergic striatal neuron
Autor:
Rainer Schindl, Marlene E. Hack, Heike Kahr, Reinhard Fritsch, Klaus J. F. Kepplinger, Isabella Derler, Sieglinde Moritz, Martin Muik, Klaus Groschner, Michael Hofbauer, Christoph Romanin
Publikováno v:
The Journal of Physiology. 577:31-44
The Ca2+-selective TRPV6 as well as the L-type Ca2+ channel are regulated by the Ca2+-binding protein calmodulin (CaM). Here, we investigated the interaction of CaM with rat (r)TRPV6 in response to alterations of intracellular Ca2+, employing Ca2+-im
Autor:
Marlene E. Hack, Klaus Groschner, Barbara Heinze, Hitomi Takanaga, Matthias A. Hediger, Manuel A. Mörtelmaier, Ji-Bin Peng, Christoph Romanin, Rainer Schindl, Reinhard Fritsch, Heike Kahr, Michael Hofbauer
Publikováno v:
The Journal of Physiology. 557:121-132
CaT1, the calcium transport protein 1 encoded by TRPV6, is able to generate a Ca(2+) conductance similar but not identical to the classical CRAC current in mucosal-type mast cells. Here we show that CaT1-derived Ca(2+) entry into HEK293 cells is effe
Autor:
Rainer, Schindl, Reinhard, Fritsch, Isaac, Jardin, Irene, Frischauf, Heike, Kahr, Martin, Muik, Maria Christine, Riedl, Klaus, Groschner, Christoph, Romanin
Publikováno v:
The Journal of Biological Chemistry
Background: Heteromerization of TRP family members can affect their physiological and biophysical properties. Results: TRPV6 and TRPC1 associate via their ankyrin-like repeat domains. Co-expression of TRPV6 and TRPC1 reduced TRPV6 expression in the p
Autor:
Reinhard Fritsch
Publikováno v:
Flora. 186:237-249
Summary Different orientation of vascular bundles can be found in laminae of genus Allium. Six different modes of connections between the vascular bundles of the sheath and those of the lamina were described. Type A is present in the Old World specie
Autor:
Rainer Schindl, Irene Frischauf, Marc Fahrner, Reinhard Fritsch, Martin Muik, Christoph Romanin, Isabella Derler
Publikováno v:
ResearcherID
Calcium (Ca2+) entry into non-excitable cells is mainly carried by store-operated channels, which serve essential functions ranging from regulation of transcription to cell growth. The best-characterized store-operated current, initially discovered i