Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Reinhard Hobi"'
The immunoglobulin heavy chain intron enhancer (Emu) not only stimulates transcription but also V(D)J recombination of chromosomally integrated recombination substrates. We aimed at reproducing this effect in recombination competent cells by transien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751e29590739f1231253173f3d057188
http://doc.rero.ch/record/297420/files/25-12-2303.pdf
http://doc.rero.ch/record/297420/files/25-12-2303.pdf
Autor:
Bernard Linder, Albert K. Beck, Dieter Seebach, Michael Limbach, Albert Eschenmoser, Reinhard Hobi, Adi M. Treasurywala, D. Michael Badine, Walter Prikoszovich
Publikováno v:
Helvetica Chimica Acta. 90:425-471
The N,O-acetal and N,O-ketal derivatives (oxazolidinones) formed from proline, and aldehydes or ketones are well-known today, and they are detectable in reaction mixtures involving proline catalysis, where they have been considered ‘parasitic dead
Publikováno v:
Journal of Molecular Biology. 261:309-314
Here we compare the regulation of V(D)J recombination in the fibroblast cell line L4 and the pre-B cell line 38B9. The former has been rendered recombination-competent by stable transfection of a genomic fragment comprising the recombination activati
Autor:
Klaus A. Neftel, Reinhard Hobi, Ulrich Hübscher, Hans Lutz, Federico Focher, Kersten Lüthi, Peter Hafkemeyer, Silvio Spadari, Andreas Pfaltz
Publikováno v:
Scopus-Elsevier
Penicillins, cephalosporins and other betalactam antibiotics are widely used antibacterial drugs. Recently it was found that some of them also have effects on proliferating eukaryotic cells (Neftel, K.A. and Hübscher, U. (1987) Antimicrob. Agents Ch
Autor:
Ulrich Hübscher, Peter Schneider, E Alteri, Klaus A. Neftel, Reinhard Hobi, Bernard Poncioni, Kathie Woods-Cook, Maja R. Walker, Janis K. Lazdins
Publikováno v:
Antiviral chemistrychemotherapy. 12(2)
Cephalosporins in aqueous solutions generate degradation products that inhibit in vitro HIV-1 replication in cell lines, as well as in primary cells (lymphocytes and macrophages). This effect is observed at concentrations that do not interfere with t
Autor:
Dieter Seebach, Albert 4;K. Beck, D. 4;Michael Badine, Michael Limbach, Albert Eschenmoser, Adi 4;M. Treasurywala, Reinhard Hobi, Walter Prikoszovich, Bernard Linder
Publikováno v:
Helvetica Chimica Acta; Mar2007, Vol. 90 Issue 3, p425-471, 47p
Publikováno v:
Experimental Cell Research. 135:331-339
Brain cortex neurons from adult mammals contain amounts of DNA elevated to between the diploid and tetraploid level. In the rat, the rise in DNA starts rapidly a few hours before birth, then slows down to taper off at 3 weeks after birth. In view of
Publikováno v:
Helvetica Chimica Acta. 57:1498-1505
The reaction sequences shown in schemes 3 and 4, represent a new method for the synthesis of a substituted pyridone-system, starting from a vinylogous amide or thioamide and malonic ester.
Autor:
Albert Eschenmoser, Reinhard Hobi, Kevin L. Brown, Lorenz Damm, Jack D. Dunitz, Christoph Kratky
Publikováno v:
Helvetica Chimica Acta. 61:3108-3135
Crystal structure analyses of five crystalline enamines together with recently published structural data for two other enamines reveal varying degree of pyramidality at the enamine nitrogen atom. The pyramidality appears to be most pronounced in enam
Autor:
Lorenz Damm, Paul Seiler, Emily F. Maverick, Noel Vanier, Reinhard Hobi, Albin Kümin, Albert Eschenmoser, Jack D. Dunitz
Publikováno v:
Helvetica Chimica Acta. 63:1158-1175
Structure of a O,N-Keteneacetal: (1RS, 8SR, 10SR, 4(15)Z)-4-Ethylidene-5-oxa-3-azatricyclo [8.4.0.03,8]tetradecane1 Methods for the preparation of a series of model compounds which were required for stereochemical studies are described: the tricyclic