Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Reiner U. Jänicke"'
Autor:
Judith Neuwahl, Chantal A. Neumann, Annika C. Fitz, Anica D. Biermann, Maja Magel, Annabelle Friedrich, Lorenz Sellin, Björn Stork, Roland P. Piekorz, Peter Proksch, Wilfried Budach, Reiner U. Jänicke, Dennis Sohn
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-14 (2024)
Abstract The targeted elimination of radio- or chemotherapy-induced senescent cells by so-called senolytic substances represents a promising approach to reduce tumor relapse as well as therapeutic side effects such as fibrosis. We screened an in-hous
Externí odkaz:
https://doaj.org/article/e1d558cf63a94e08b3b6bbd7624c9ad0
Autor:
Soha A. Hassan, Amira A. H. Ali, Dennis Sohn, Ulrich Flögel, Reiner U. Jänicke, Horst‐Werner Korf, Charlotte vonGall
Publikováno v:
Cancer Medicine, Vol 10, Iss 21, Pp 7712-7725 (2021)
Abstract This study investigates whether a chronotherapeutic treatment of hepatocellular carcinoma (HCC) may improve treatment efficacy and mitigate side effects on non‐tumoral liver (NTL). HCC was induced in Per2::luc mice which were irradiated at
Externí odkaz:
https://doaj.org/article/23184073e86e41f8a8664be2650268d9
Autor:
Deborah Ingenhag, Sven Reister, Franziska Auer, Sanil Bhatia, Sarah Wildenhain, Daniel Picard, Marc Remke, Jessica I. Hoell, Andreas Kloetgen, Dennis Sohn, Reiner U. Jänicke, Gesine Koegler, Arndt Borkhardt, Julia Hauer
Publikováno v:
Haematologica, Vol 104, Iss 1 (2019)
The homeobox gene HLXB9 encodes for the transcription factor HB9, which is essential for pancreatic as well as motor neuronal development. Beside its physiological expression pattern, aberrant HB9 expression has been observed in several neoplasias. E
Externí odkaz:
https://doaj.org/article/54d17398874743d28e9bc9dfe026294a
Autor:
Laura Bergmann, Alexander Lang, Christoph Bross, Simone Altinoluk-Hambüchen, Iris Fey, Nina Overbeck, Anja Stefanski, Constanze Wiek, Andreas Kefalas, Patrick Verhülsdonk, Christian Mielke, Dennis Sohn, Kai Stühler, Helmut Hanenberg, Reiner U. Jänicke, Jürgen Scheller, Andreas S. Reichert, Mohammad Reza Ahmadian, Roland P. Piekorz
Publikováno v:
Cells, Vol 9, Iss 9, p 1950 (2020)
The stress-inducible and senescence-associated tumor suppressor SIRT4, a member of the family of mitochondrial sirtuins (SIRT3, SIRT4, and SIRT5), regulates bioenergetics and metabolism via NAD+-dependent enzymatic activities. Next to the known mitoc
Externí odkaz:
https://doaj.org/article/a6074553cc1f43e5aa630ee3f5397b69
Supplementary Figure 3 from Caspase-3–Dependent Mitotic Checkpoint Inactivation by the Small-Molecule Inducers of Mitotic Slippage SU6656 and Geraldol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94a2bb2ba4814e1b45537adb06fc498
https://doi.org/10.1158/1535-7163.22497117.v1
https://doi.org/10.1158/1535-7163.22497117.v1
Supplementary Figure 2 from Caspase-3–Dependent Mitotic Checkpoint Inactivation by the Small-Molecule Inducers of Mitotic Slippage SU6656 and Geraldol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bf642759f76713dc57f1c0c945607d
https://doi.org/10.1158/1535-7163.22497120.v1
https://doi.org/10.1158/1535-7163.22497120.v1
Microtubule-targeting cancer drugs such as paclitaxel block cell-cycle progression at mitosis by prolonged activation of the mitotic checkpoint. Cells can spontaneously escape mitotic arrest and enter interphase without chromosome segregation by a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88e9fcc4f0576b290351d853513f049a
https://doi.org/10.1158/1535-7163.c.6535503
https://doi.org/10.1158/1535-7163.c.6535503
Supplementary Figure and Table Legends from Caspase-3–Dependent Mitotic Checkpoint Inactivation by the Small-Molecule Inducers of Mitotic Slippage SU6656 and Geraldol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adf5447b68e87e98f62b11db850dd33
https://doi.org/10.1158/1535-7163.22497114.v1
https://doi.org/10.1158/1535-7163.22497114.v1
Supplementary Table 1 from Caspase-3–Dependent Mitotic Checkpoint Inactivation by the Small-Molecule Inducers of Mitotic Slippage SU6656 and Geraldol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88919072e1e83a23ec180b2913389983
https://doi.org/10.1158/1535-7163.22497111
https://doi.org/10.1158/1535-7163.22497111
Supplementary Figure 1 from Caspase-3–Dependent Mitotic Checkpoint Inactivation by the Small-Molecule Inducers of Mitotic Slippage SU6656 and Geraldol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ffd64eaeecbb76c0b12071a36392b29
https://doi.org/10.1158/1535-7163.22497123
https://doi.org/10.1158/1535-7163.22497123