Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Reiner Schulz"'
Autor:
Adam R. Prickett, Bertille Montibus, Nikolaos Barkas, Samuele M. Amante, Maurício M. Franco, Michael Cowley, William Puszyk, Matthew F. Shannon, Melita D. Irving, Marta Madon-Simon, Andrew Ward, Reiner Schulz, H. Scott Baldwin, Rebecca J. Oakey
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Dopa decarboxylase (DDC) synthesizes serotonin in the developing mouse heart where it is encoded by Ddc_exon1a, a tissue-specific paternally expressed imprinted gene. Ddc_exon1a shares an imprinting control region (ICR) with the imprinted, maternally
Externí odkaz:
https://doaj.org/article/ae3e5048d96b4447a5c8d0554890d0bb
Autor:
Hélène Bauby, Christopher C. Ward, Rupert Hugh-White, Chad M. Swanson, Reiner Schulz, Caroline Goujon, Michael H. Malim
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
HIV-1, while now treatable, remains an important human pathogen causing significant morbidity and mortality globally. The virus predominantly infects CD4 +
Externí odkaz:
https://doaj.org/article/a112ccecaca44e1789b7aff2495726d9
Autor:
Federico Rossi, Alessandro Crnjar, Federico Comitani, Rodrigo Feliciano, Leonie Jahn, George Malim, Laura Southgate, Emily Kay, Rebecca Oakey, Richard Buggs, Andy Moir, Logan Kistler, Ana Rodriguez Mateos, Carla Molteni, Reiner Schulz
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Tree ring features are affected by environmental factors and therefore are the basis for dendrochronological studies to reconstruct past environmental conditions. Oak wood often provides the data for these studies because of the durability of oak hea
Externí odkaz:
https://doaj.org/article/2693f679d5b74116945a1b30943a6d32
Autor:
Luis Apolonia, Reiner Schulz, Tomaž Curk, Paula Rocha, Chad M Swanson, Torsten Schaller, Jernej Ule, Michael H Malim
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004609 (2015)
The apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3) proteins are cell-encoded cytidine deaminases, some of which, such as APOBEC3G (A3G) and APOBEC3F (A3F), act as potent human immunodeficiency virus type-1 (HIV-1) restric
Externí odkaz:
https://doaj.org/article/544033fc38484d168780e29c2d7fbbdc
Autor:
Lara A. Underkoffler, Erikka Carr, Anthony Nelson, Matthew J. Ryan, Reiner Schulz, Kathleen M. Loomes
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/b1d9705d1c394efd8408a6cd611663cf
Autor:
Lara A Underkoffler, Erikka Carr, Anthony Nelson, Matthew J Ryan, Reiner Schulz, Kathleen M Loomes
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84383 (2013)
Alagille syndrome is an autosomal dominant disorder involving bile duct paucity and cholestasis in addition to cardiac, skeletal, ophthalmologic, renal and vascular manifestations. Mutations in JAG1, encoding a ligand in the Notch signaling pathway,
Externí odkaz:
https://doaj.org/article/bcd6163d052345859034a419be6ac394
Autor:
Michael Cowley, Anna de Burca, Ruth B McCole, Mandeep Chahal, Ghazal Saadat, Rebecca J Oakey, Reiner Schulz
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18953 (2011)
Genomic imprinting is a form of gene dosage regulation in which a gene is expressed from only one of the alleles, in a manner dependent on the parent of origin. The mechanisms governing imprinted gene expression have been investigated in detail and h
Externí odkaz:
https://doaj.org/article/6940171e19984f24aa1a102cb53c3f72
Autor:
Reiner Schulz, Charlotte Proudhon, Timothy H Bestor, Kathryn Woodfine, Chyuan-Sheng Lin, Shau-Ping Lin, Marine Prissette, Rebecca J Oakey, Déborah Bourc'his
Publikováno v:
PLoS Genetics, Vol 6, Iss 11, p e1001214 (2010)
In mammals, imprinted gene expression results from the sex-specific methylation of imprinted control regions (ICRs) in the parental germlines. Imprinting is linked to therian reproduction, that is, the placenta and imprinting emerged at roughly the s
Externí odkaz:
https://doaj.org/article/cbcdb28068e443e8a5f43a99595ce97d
Publikováno v:
PLoS Genetics, Vol 3, Iss 2, p e20 (2007)
Imprinted genes undergo epigenetic modifications during gametogenesis, which lead to transcriptional silencing of either the maternally or the paternally derived allele in the subsequent generation. Previous work has suggested an association between
Externí odkaz:
https://doaj.org/article/9e4645a22f644ffaa18238795672ef9b
Autor:
Boris Bonaventure, Antoine Rebendenne, Ana Luiza Chaves Valadão, Mary Arnaud‐Arnould, Ségolène Gracias, Francisco Garcia de Gracia, Joe McKellar, Emmanuel Labaronne, Marine Tauziet, Valérie Vivet‐Boudou, Eric Bernard, Laurence Briant, Nathalie Gros, Wassila Djilli, Valérie Courgnaud, Hugues Parrinello, Stéphanie Rialle, Mickaël Blaise, Laurent Lacroix, Marc Lavigne, Jean‐Christophe Paillart, Emiliano P Ricci, Reiner Schulz, Nolwenn Jouvenet, Olivier Moncorgé, Caroline Goujon
Publikováno v:
EMBO Reports
EMBO Reports, 2022, ⟨10.15252/embr.202154061⟩
EMBO Reports, 2022, ⟨10.15252/embr.202154061⟩
Genome-wide screens are powerful approaches to unravel regulators of viral infections. Here, a CRISPR screen identifies the RNA helicase DDX42 as an intrinsic antiviral inhibitor of HIV-1. Depletion of endogenous DDX42 increases HIV-1 DNA accumulatio