Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Reiner LAMMERS"'
Autor:
Gwendlyn Kollmorgen, Birgit Bossenmaier, Gerhard Niederfellner, Hans-Ulrich Häring, Reiner Lammers
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53050 (2012)
Cub domain containing protein 1 (CDCP1) is strongly expressed in tumors derived from lung, colon, ovary, or kidney. It is a membrane protein that is phosphorylated and then bound by Src family kinases. Although expression and phosphorylation of CDCP1
Externí odkaz:
https://doaj.org/article/a6e3c84cdaae42d19e6d414980fa15bd
Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ
Autor:
Anna Pujol, Hans-Ulrich Häring, Felicia Gerst, Anita M. Hennige, Fausto Machicao, Gabriele Kaiser, Fatima Bosch, Tina Sartorius, Madhura Panse, Reiner Lammers, Susanne Ullrich
Publikováno v:
Diabetologia. 58:2819-2831
Forkhead box protein O1 (FOXO1) is a transcription factor essential for beta cell fate. Protein kinase B-dependent phosphorylation of FOXO1 at S256 (P-FOXO1) enables its binding to 14-3-3 dimers and nuclear export. Dephosphorylated FOXO1 enters nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46285eabf2d0a8de8dcf5e26b2b21f88
https://doi.org/10.1007/s00125-015-3744-z
https://doi.org/10.1007/s00125-015-3744-z
Autor:
Angelika Hartung, Hans-Ulrich Häring, Martina Melzer, Anna-Maria Ordelheide, Reiner Lammers, Harald Staiger
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833(12):2803-2811
Akt kinases are important mediators of the insulin signal, and some Akt substrates are directly involved in glucose homeostasis. Recently, Girdin has been described as an Akt substrate that is expressed ubiquitously in mammals. Cells overexpressing G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e79dc960d2ba465ed63025b707c0a3a
Autor:
Gloria J. Spohn, Natascha Rieder, Frieder Bauss, Alexander Lifke, Suzana Vega Harring, Reiner Lammers, Birgit Bossenmaier, Gwendlyn Kollmorgen, Gerhard Niederfellner, Helmut Burtscher
Publikováno v:
Molecular Oncology. 7:1142-1151
CUB-domain-containing-protein-1 (CDCP1) is an integral membrane protein whose expression is up-regulated in various cancer types. Although high CDCP1 expression has been correlated with poor prognosis in lung, breast, pancreas, and renal cancer, its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7031f8f061a8cca43d0b53c8620056
https://doi.org/10.1016/j.molonc.2013.08.009
https://doi.org/10.1016/j.molonc.2013.08.009
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 107:97-106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8c8489acb1a768e1d6fb986e64f1fc
https://doi.org/10.1055/s-0029-1212082
https://doi.org/10.1055/s-0029-1212082
Autor:
Fritz Schick, Antje Bornemann, Sylvie Franckhauser, Martin Heni, Anita M. Hennige, Jürgen Machann, Anna Pujol, Tina Sartorius, Stefan Kroeber, Rainer Lehmann, Hans-Ulrich Häring, Harald Staiger, Cora Weigert, Miriam Hoene, Andreas Peter, Fatima Bosch, Reiner Lammers
Publikováno v:
Journal of Cellular and Molecular Medicine
Among the multitude of dysregulated signalling mechanisms that comprise insulin resistance in divergent organs, the primary events in the development of type 2 diabetes are not well established. As protein kinase C (PKC) activation is consistently pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d3cee826142458e4b5aed53753e05b
https://doi.org/10.1111/j.1582-4934.2008.00629.x
https://doi.org/10.1111/j.1582-4934.2008.00629.x
Autor:
Albet S, Peter Weyrich, Fausto Machicao, HU Häring, Andreas Fritsche, Reiner Lammers, Norbert Stefan
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 117:83-87
AIMS: Procolipase (CLPS) is secreted from the exocrine pancreas into the gastrointestinal tract and becomes proteolytically cleaved into colipase and the pentapeptide enterostatin. While colipase is an indispensable cofactor for pancreatic lipase, en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea87fd25724ce8c608b039b25daeb12f
https://doi.org/10.1055/s-2008-1078733
https://doi.org/10.1055/s-2008-1078733
Autor:
Cornelia Thedieck, Reiner Lammers, Gerd Klein, Stefan Stevanovic, Hubert Kalbacher, Ulrich Kratzer
Publikováno v:
Journal of Molecular Biology. 378:145-153
The Ca(2+)-dependent membrane-spanning classical cadherins bind directly to cytosolic catenins. This cadherin-catenin interaction is known to be critical for the fundamental role of cadherins in cell-cell adhesion. The small subfamily of the 7D-cadhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74aef338260da2cf6331416b2cc2363
https://doi.org/10.1016/j.jmb.2008.02.008
https://doi.org/10.1016/j.jmb.2008.02.008
Publikováno v:
Genes to Cells. 12:63-73
The extracellular domains of receptor-type protein-tyrosine phosphatases (PTPs) contain a diverse range of protein modules like fibronectin- or immunoglobulin-like structures. These are frequently expressed in a tissue- and development specific manne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637eb19385f5efbcf416100ed4e272f9
https://doi.org/10.1111/j.1365-2443.2006.01034.x
https://doi.org/10.1111/j.1365-2443.2006.01034.x
Publikováno v:
Diabetologia. 48:669-674
Partitioning-defective protein-6alpha (Par6alpha) has recently been demonstrated to negatively regulate insulin signalling in murine myoblasts. To address whether Par6alpha plays a role in human physiology, the present study investigated whether muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9b2de8e2815a365b8c6f8f18fcb100
https://doi.org/10.1007/s00125-005-1688-4
https://doi.org/10.1007/s00125-005-1688-4