Unraveling the dynamics of hepatitis C virus adaptive mutations and their impact on antiviral responses in primary human hepatocytes.

Autor: Frericks N; Institute for Experimental Virology, TWINCORE, Hannover, Germany.; Department for Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany., Brown RJP; Department for Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany.; Division of Veterinary Medicine, Paul Ehrlich Institute, Langen, Germany., Reinecke BM; Institute for Experimental Virology, TWINCORE, Hannover, Germany., Herrmann M; Division of Veterinary Medicine, Paul Ehrlich Institute, Langen, Germany., Brüggemann Y; Department for Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany., Todt D; Department for Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany.; European Virus Bioinformatics Center (EVBC), Jena, Germany., Miskey C; Division of Medical Biotechnology, Paul Ehrlich Institute, Langen, Germany., Vondran FWR; Department for General, Visceral and Transplant Surgery, Hannover Medical School, Hannover, Germany.; Clinic for General, Visceral and Transplant Surgery, University Hospital RWTH Aachen, Aachen, Germany.; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany., Steinmann E; Department for Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany., Pietschmann T; Institute for Experimental Virology, TWINCORE, Hannover, Germany.; German Center for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany., Sheldon J; Institute for Experimental Virology, TWINCORE, Hannover, Germany.

Publikováno v: Journal of virology [J Virol] 2024 Mar 19; Vol. 98 (3), pp. e0192123. Date of Electronic Publication: 2024 Feb 06.