Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Reine-Solange Sauer"'
Autor:
Beatrice Oehler, Katrin Kistner, Corinna Martin, Jürgen Schiller, Rafaela Mayer, Milad Mohammadi, Reine-Solange Sauer, Milos R. Filipovic, Francisco R. Nieto, Jan Kloka, Diana Pflücke, Kerstin Hill, Michael Schaefer, Marzia Malcangio, Peter W. Reeh, Alexander Brack, Robert Blum, Heike L. Rittner
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-22 (2017)
Abstract Phospholipids occurring in cell membranes and lipoproteins are converted into oxidized phospholipids (OxPL) by oxidative stress promoting atherosclerotic plaque formation. Here, OxPL were characterized as novel targets in acute and chronic i
Externí odkaz:
https://doaj.org/article/a6c20966bd864799baf52d5a980c648e
Autor:
Friedrich Schöppler, Jens Broscheit, Reine-Solange Sauer, Adel Ben-Kraiem, Ivo Krummenacher, Helga Stopper, Norbert Roewer, Shaobing Yang, Holger Braunschweig, Ulrike Holzgrabe, Milad Mohammadi, Beatrice Oehler, Heike L. Rittner, Ezgi Eylül Bankoglu, Alexander Brack, Paul Güntzel
Publikováno v:
Antioxidants & Redox Signaling. 34:1260-1279
Aims: Delphinidin (DEL) is a plant-derived antioxidant with clinical potential to treat inflammatory pain but suffers from poor solubility and low bioavailability. The aim of the study was to devel...
Autor:
Mariam Sobhy Atalla, Reine-Solange Sauer, Robert Blum, Anna-Lena Bettenhausen, Alexander Brack, Heike L. Rittner, Maria Popp, Adel Ben-Kraiem, Kathrin Doppler, Carla Norwig
Publikováno v:
Journal of Molecular Medicine (Berlin, Germany)
Abstract Diabetic polyneuropathy (DPN) is the most common complication in diabetes and can be painful in up to 26% of all diabetic patients. Peripheral nerves are shielded by the blood-nerve barrier (BNB) consisting of the perineurium and endoneurial
Autor:
Liu Hu, Reine-Solange Sauer, Ann-Kristin Reinhold, Egle M. Mambretti, Susanne M. Krug, Michael Fromm, Alexander Brack, Shaobing Yang, Jeremy Tsung-Chieh Chen, Heike L. Rittner
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1865(6)
The blood-nerve barrier (BNB) consisting of the perineurium and endoneurial vessels is sealed by tight junction proteins. BNB alterations are a crucial factor in the pathogenesis of peripheral neuropathies. However, barrier opening, e.g. by tissue pl
Autor:
Juliane Kirchner, Shaobing Yang, Mathias Leinders, Liu Hu, Alexander Brack, Heike L. Rittner, Reine-Solange Sauer, Claudia Sommer
Publikováno v:
Annals of the New York Academy of Sciences
The blood-spinal cord barrier (BSCB) prevents leakage of molecules, such as pronociceptive mediators, into the spinal cord, but its role in the pathophysiology of neuropathic pain is not completely understood. Rats with chronic constriction injury (C
Autor:
Heike L. Rittner, Alexander Brack, Jens-Albert Broscheit, Sergey Shityakov, Tamás Sohajda, Norbert Roewer, Reine-Solange Sauer
Publikováno v:
Anesthesia and analgesia. 124(2)
BACKGROUND Inhibitors of cyclooxygenase, which block the formation of prostaglandin (PG) E2, are the standard treatment of inflammatory pain. These drugs, however, have serious gastrointestinal, renal, and cardiovascular side effects that limit their
Autor:
Reiner F. Haseloff, Denise Zwanziger, Heike L. Rittner, Christian Bellmann, Ingolf E. Blasig, Ramona Günther, Reine-Solange Sauer, Eberhard Krause, Christian Staat, Sebastian Dabrowski
Publikováno v:
Antioxidants & redox signaling, 22(1): 1-14
The paracellular cleft within epithelia/endothelia is sealed by tight junction (TJ) proteins. Their extracellular loops (ECLs) are assumed to control paracellular permeability and are targets of pathogenes. We demonstrated that claudin-1 is crucial f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faabd6dc9aefa86e6f9b31ad2706fa03
https://europepmc.org/articles/PMC4270150/
https://europepmc.org/articles/PMC4270150/
Autor:
Dagmar Hackel, Susanne M. Krug, Natalia Konasin, Alexander Brack, Shaobing Yang, Christian Staat, Sebastian Dabrowski, Judith Bosten, Heike L. Rittner, Benedikt Niedermirtl, Ramona Günther, Claudia Sommer, Reine-Solange Sauer, Ingolf E. Blasig, Kathrin Doppler
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 185
The blood-nerve barrier consists of the perineurium and endoneurial vessels. The perineurial barrier is composed of a basal membrane and a layer of perineurial cells sealed by tight junction proteins preventing e.g. application of analgesics for sele