Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Reine Note"'
Autor:
Camilly P. Pires de Mello, Carlos Carmona-Moran, Christopher W. McAleer, Julian Perez, Elizabeth A. Coln, Christopher J. Long, Carlota Oleaga, Anne Riu, Reine Note, Silvia Teissier, Jessica Langer, James J. Hickman
Publikováno v:
Lab Chip
Body-on-a-chip in vitro systems are a promising technology that aims to increase the predictive power of drug efficacy and toxicity in humans when compared to traditional animal models. Here, we developed a new heart-liver body-on-a-chip system with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd99dfc816c65003bd4885bcce6c968
https://doi.org/10.1039/c9lc00861f
https://doi.org/10.1039/c9lc00861f
Autor:
Carlota Oleaga, Anne Riu, Sandra Rothemund, Andrea Lavado, Christopher W. McAleer, Christopher J. Long, Keisha Persaud, Narasimhan Sriram Narasimhan, My Tran, Jeffry Roles, Carlos A. Carmona-Moran, Trevor Sasserath, Daniel H. Elbrecht, Lee Kumanchik, L. Richard Bridges, Candace Martin, Mark T. Schnepper, Gail Ekman, Max Jackson, Ying I. Wang, Reine Note, Jessica Langer, Silvia Teissier, James J. Hickman
Publikováno v:
Biomaterials. 182:176-190
Regulation of cosmetic testing and poor predictivity of preclinical drug studies has spurred efforts to develop new methods for systemic toxicity. Current in vitro assays do not fully represent physiology, often lacking xenobiotic metabolism. Functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33285a19753400fcca5f893bc71584ac
https://doi.org/10.1016/j.biomaterials.2018.07.062
https://doi.org/10.1016/j.biomaterials.2018.07.062
Autor:
Carlota Oleaga, Andrea Lavado, Anne Riu, Sandra Rothemund, Carlos A. Carmona‐Moran, Keisha Persaud, Andrew Yurko, Jennifer Lear, Narasimhan Sriram Narasimhan, Christopher J. Long, Frank Sommerhage, Lee Richard Bridges, Yunqing Cai, Candace Martin, Mark T. Schnepper, Arindom Goswami, Reine Note, Jessica Langer, Silvia Teissier, José Cotovio, James J. Hickman
Publikováno v:
Adv Funct Mater
The goal of human-on-a-chip systems is to capture multi-organ complexity and predict the human response to compounds within physiologically relevant platforms. The generation and characterization of such systems is currently a focal point of research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56649b7db9cc01f84898d059830af096
https://europepmc.org/articles/PMC9113405/
https://europepmc.org/articles/PMC9113405/
Autor:
Avner Ehrlich, Sabina Tsytkin-Kirschenzweig, Konstantinos Ioannidis, Muneef Ayyash, Anne Riu, Reine Note, Gladys Ouedraogo, Jan Vanfleteren, Merav Cohen, Yaakov Nahmias
Publikováno v:
Lab on a Chip
Drug development is currently hampered by the inability of animal experiments to accurately predict human response. While emerging organ on chip technology offers to reduce risk using microfluidic models of human tissues, the technology still mostly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8749b4d8113997869c230f70cf2c468d
Autor:
Daniela Nedelcheva, Stoyanka Stoeva, Sabcho Dimitrov, Ann Detroyer, Aziz Fadli, Reine Note, Delphine Blanchet, Ovanes Mekenyan
Publikováno v:
Computational Toxicology. 12:100109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e514a1064e9cd2fcd050e9d0012b2535
https://doi.org/10.1016/j.comtox.2019.100109
https://doi.org/10.1016/j.comtox.2019.100109
Autor:
Reine Note, Caroline Maisonneuve, Philippe Lettéron, Gilles Peytavin, Fatima Djouadi, Anissa Igoudjil, Marie-Christine Guimont, Michel Biour, Dominique Pessayre, Bernard Fromenty
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:3384-3392
Although treatments with nucleoside reverse transcriptase inhibitors (NRTIs) can modify fat metabolism and fat distribution in humans, the mechanisms of these modifications and the roles of diverse NRTIs are unknown. We studied the mitochondrial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8040ab5f843b878ed97162e90e47c886
https://doi.org/10.1128/aac.47.11.3384-3392.2003
https://doi.org/10.1128/aac.47.11.3384-3392.2003
Autor:
Renée Pontikis, Valérie Dollé, Jean Guillaumel, Elsa Dechaux, Reine Note, Chi Hung Nguyen, Michel Legraverend, Emile Bisagni, Anne-Marie Aubertin, David S. Grierson, Claude Monneret
Publikováno v:
Journal of Medicinal Chemistry. 43:1927-1939
To test the concept that HIV reverse transcriptase could be effectively inhibited by "mixed site inhibitors", a series of seven conjugates containing both a nucleoside analogue component (AZT 1, ddC 2) and a nonnucleoside type inhibitor (HEPT analogu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bf6226eca8e8aebfb4b359afe7bd40
https://doi.org/10.1021/jm991125l
https://doi.org/10.1021/jm991125l
Autor:
Stephanie Ringeissen, Laurent Marrot, Reine Note, Anita Labarussiat, Stéphane Imbert, Milen Todorov, Ovanes Mekenyan, Jean-Roch Meunier
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 25(1)
Phototoxicity is of increasing concern in dermatology, since modern lifestyle is often associated with exposure to sunlight. The most commonly reported process is via oxidative reactions. Therefore characterizing the "photo-pro-oxidant" potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0b5d52a5eaa7711323721d527898e7
https://pubmed.ncbi.nlm.nih.gov/20932893
https://pubmed.ncbi.nlm.nih.gov/20932893