Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Improving genetic prediction by leveraging genetic correlations among human diseases and traits

Autor: Maier, R. M., Zhu, Z., Lee, S. H., Trzaskowski, M., Ruderfer, D. M., Stahl, E. A., Ripke, S., Wray, N. R., Yang, J., Visscher, P. M., Robinson, M. R., Forstner, A. J., Mcquillin, A., Trubetskoy, V., Wang, W., Wang, Y., Coleman, J. R. I., Gaspar, H. A., Leeuw, C. A., Whitehead Pavlides, J. M., Olde Loohuis, L. M., Pers, T. H., Lee, P. H., Charney, A. W., Dobbyn, A. L., Huckins, L., Boocock, J., Giambartolomei, C., Roussos, P., Mullins, N., Awasthi, S., Agerbo, E., Als, T. D., Pedersen, C. B., Grove, J., Kupka, R., Regeer, E. J., Anjorin, A., Casas, M., Mahon, P. B., Allardyce, J., Escott-Price, V., Forty, L., Fraser, C., Kogevinas, M., Frank, J., Streit, F., Strohmaier, J., Treutlein, J., Witt, S. H., Kennedy, J. L., Strauss, J. S., Garnham, J., O Donovan, C., Slaney, C., Steinberg, S., Thorgeirsson, T. E., Hautzinger, M., Steffens, M., Perlis, R. H., Sánchez-Mora, C., Hipolito, M., Lawson, W. B., Nwulia, E. A., Levy, S. E., Foroud, T. M., Jamain, S., Young, A. H., Mckay, J. D., Albani, D., Zandi, P., Potash, J. B., Zhang, P., Raymond Depaulo, J., Bergen, S. E., Juréus, A., Karlsson, R., Kandaswamy, R., Mcguffin, P., Rivera, M., Lissowska, J., Cruceanu, C., Lucae, S., Cervantes, P., Budde, M., Gade, K., Heilbronner, U., Pedersen, M. G., Morris, D. W., Weickert, C. S., Weickert, T. W., Macintyre, D. J., Lawrence, J., Elvsåshagen, T., Smeland, O. B., Djurovic, S., Xi, S., Green, E. K., Czerski, P. M., Hauser, J., Xu, W., Vedder, H., Oruc, L., Spijker, A. T., Gordon, S. D., Medland, S. E., Curtis, D., Mühleisen, T. W., Badner, J. A., Scheftner, W. A., Sigurdsson, E., Schork, N. J., Schatzberg, A. F., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hansen, C. S., Knowles, J. A., Szelinger, S., Montgomery, G. W., Boks, M., Adolfsson, A. N., Hoffmann, P., Bauer, M., Pfennig, A., Leber, M., Kittel-Schneider, S., Reif, A., Del-Favero, J., Fischer, S. B., Herms, S., Reinbold, C. S., Degenhardt, F., Koller, A. C., Maaser, A., Ori, A. P. S., Dale, A. M., Fan, C. C., Greenwood, T. A., Nievergelt, C. M., Shehktman, T., Shilling, P. D., Byerley, W., Bunney, W., Alliey-Rodriguez, N., Clarke, T. K., Liu, C., Coryell, W., Akil, H., Burmeister, M., Flickinger, M., Li, J. Z., Mcinnis, M. G., Meng, F., Thompson, R. C., Watson, S. J., Zollner, S., Guan, W., Green, M. J., Craig, D., Sobell, J. L., Milani, L., Gordon-Smith, Katherine, Knott, Sarah, Perry, Amy, Parra, J. G., Mayoral, F., Rivas, F., Rice, J. P., Barchas, J. D., Børglum, A. D., Mortensen, P. B., Mors, O., Grigoroiu-Serbanescu, M., Bellivier, F., Etain, B., Leboyer, M., Ramos-Quiroga, J. A., Agartz, I., Amin, F., Azevedo, M. H., Bass, N., Black, D. W., Blackwood, D. H. R., Bruggeman, R., Buccola, N. G., Choudhury, K., Cloninger, C. R., Corvin, A., Craddock, N., Daly, M. J., Datta, S., Donohoe, G. J., Duan, J., Dudbridge, F., Fanous, A., Freedman, R., Freimer, N. B., Friedl, M., Gill, M., Gurling, H., Haan, L., Hamshere, M. L., Hartmann, A. M., Holmans, P. A., Kahn, R. S., Keller, M. C., Kenny, E., Kirov, G. K., Krabbendam, L., Krasucki, R., Lencz, T., Levinson, D. F., Lieberman, J. A., Lin, D. -Y, Linszen, D. H., Magnusson, P. K. E., Maier, W., Malhotra, A. K., Mattheisen, M., Mattingsdal, M., Mccarroll, S. A., Medeiros, H., Melle, I., Milanova, V., Myin-Germeys, I., Neale, B. M., Ophoff, R. A., Owen, M. J., Pimm, J., Purcell, S. M., Puri, V., Digby Quested, Rossin, L., Sanders, A. R., Shi, J., Sklar, P., St Clair, D., Stroup, T. S., Os, J., Wiersma, D., Zammit, S.

Publikováno v: Nature Communications
Nature Communications, 9(1):02769-6. Nature Publishing Group
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J, Visscher, P M, Robinson, M R, Forstner, A J, Mcquillin, A, Trubetskoy, V, Wang, W, Wang, Y, Coleman, J R I, Gaspar, H A, De Leeuw, C A, Whitehead Pavlides, J M, Olde Loohuis, L M, Pers, T H, Lee, P H, Charney, A W, Dobbyn, A L, Huckins, L, Boocock, J, Giambartolomei, C, Roussos, P, Mullins, N, Awasthi, S, Agerbo, E, Als, T D, Pedersen, C B, Grove, J, Kupka, R, Regeer, E J, Anjorin, A, Casas, M, Mahon, P B, Allardyce, J, Escott-Price, V, Forty, L, Fraser, C, Kogevinas, M, Frank, J, Streit, F, Strohmaier, J & Treutlein, J 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 02769-6 . https://doi.org/10.1038/s41467-017-02769-6
Nature Communications, 9(1). Nature Publishing Group
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature communications, 9(1):02769-6. Nature Publishing Group
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J, Visscher, P M, Robinson, M R, Forstner, A J, Mcquillin, A, Trubetskoy, V, Wang, W, Wang, Y, Coleman, J R I, Gaspar, H L A, de Leeuw, C A, Whitehead Pavlides, J M, Olde Loohuis, L M, Pers, T H, Lee, P H, Charney, A W, Dobbyn, A L, Huckins, L, Boocock, J, Giambartolomei, C, Roussos, P, Mullins, N, Awasthi, S, Agerbo, E, Als, T D, Pedersen, C B C, Grove, J, Kupka, R, Regeer, E J, Anjorin, A, Casas, M, Mahon, P B, Allardyce, J, Escott-Price, V, Forty, L, Fraser, C, Kogevinas, M, Frank, J, Streit, F, Strohmaier, J, Treutlein, J, Witt, S H, Kennedy, J L, Strauss, J S, Garnham, J, O'donovan, C, Slaney, C, Steinberg, S, Thorgeirsson, T E, Hautzinger, M, Steffens, M, Perlis, R H, Sánchez-Mora, C, Hipolito, M, Lawson, W B, Nwulia, E A, Levy, S E, Foroud, T M, Jamain, S, Young, A H, Mckay, J D, Albani, D, Zandi, P, Potash, J B, Zhang, P, Raymond Depaulo, J, Bergen, S E, Juréus, A, Karlsson, R, Kandaswamy, R, Mcguffin, P, Rivera, M, Lissowska, J, Cruceanu, C, Lucae, S, Cervantes, P, Budde, M, Gade, K, Heilbronner, U, Pedersen, M G, Morris, D W, Weickert, C S, Weickert, T W, Macintyre, D J, Lawrence, J, Elvsåshagen, T, Smeland, O B, Djurovic, S, Xi, S, Green, E K, Czerski, P M, Hauser, J, Xu, W, Vedder, H, Oruc, L, Spijker, A T, Gordon, S D, Medland, S E, Curtis, D, Mühleisen, T W, Badner, J, Scheftner, W A, Sigurdsson, E, Schork, N J, Schatzberg, A F, Bækvad-Hansen, M, Bybjerg-Grauholm, J, Hansen, C S H, Knowles, J A, Szelinger, S, Montgomery, G W, Boks, M, Adolfsson, A N, Hoffmann, P, Bauer, M, Pfennig, A, Leber, M, Kittel-Schneider, S, Reif, A, del-Favero, J, Fischer, S B, Herms, S, Reinbold, C L S, Degenhardt, F, Koller, A C, Maaser, A, Ori, A, Dale, A M, Fan, C C, Greenwood, T A, Nievergelt, C M, Shehktman, T, Shilling, P D, Byerley, W, Bunney, W, Alliey-Rodriguez, N, Clarke, T-K, Liu, C, Coryell, W, Akil, H, Burmeister, M, Flickinger, M, Li, J Z, Mcinnis, M G, Meng, F, Thompson, R C, Watson, S J, Zollner, S, Guan, W, Green, M J, Craig, D, Sobell, J L, Milani, L, Gordon-Smith, K, Knott, S V, Perry, A, Parra, J G, Mayoral, F, Rivas, F, Rice, J P, Barchas, J D, Børglum, A D, Mortensen, P B, Mors, O, Grigoroiu-Serbanescu, M, Bellivier, F, Etain, B, Leboyer, M, Ramos-Quiroga, J A, Agartz, I, Amin, F, Azevedo, M H, Bass, N, Black, D W, Blackwood, D H R, Bruggeman, R, Buccola, N G, Choudhury, K, Cloninger, C R, Corvin, A, Craddock, N, Daly, M J, Datta, S, Donohoe, G J, Duan, J, Dudbridge, F, Fanous, A, Freedman, R, Freimer, N B, Friedl, M, Gill, M, Gurling, H, de Haan, L, Hamshere, M L, Hartmann, A M, Holmans, P A, Kahn, R S, Keller, M C, Kenny, E, Kirov, G K, Krabbendam, L, Krasucki, R, Lencz, T, Levinson, D F, Lieberman, J A, Lin, D-Y, Linszen, D H, Magnusson, P K E, Maier, W, Malhotra, A K, Mattheisen, M, Mattingsdal, M, Mccarroll, S A, Medeiros, H, Melle, I, Milanova, V, Myin-Germeys, I, Neale, B M, Ophoff, R A, Owen, M J, Pimm, J, Purcell, S M, Puri, V, Quested, D J, Rossin, L, Sanders, A R, Shi, J, Sklar, P, St Clair, D, Stroup, T S, van Os, J, Wiersma, D & Zammit, S 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 02769-6 . https://doi.org/10.1038/s41467-017-02769-6
Nature communications, vol. 9, no. 1, pp. 989
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J & Visscher, P M & Robinson, M R 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 989 . https://doi.org/10.1038/s41467-017-02769-6
Maier, R M, Zhu, Z, Lee, S H, Trzaskowski, M, Ruderfer, D M, Stahl, E A, Ripke, S, Wray, N R, Yang, J, Visscher, P M, Robinson, M R, Forstner, A J, Mcquillin, A, Trubetskoy, V, Wang, W, Wang, Y, Coleman, J R I, Gaspar, H A, De Leeuw, C A, Whitehead Pavlides, J M, Olde Loohuis, L M, Pers, T H, Lee, P H, Charney, A W, Dobbyn, A L, Huckins, L, Boocock, J, Giambartolomei, C, Roussos, P, Mullins, N, Awasthi, S, Agerbo, E, Als, T D, Pedersen, C B, Grove, J, Kupka, R, Regeer, E J, Anjorin, A, Casas, M, Mahon, P B, Allardyce, J, Escott-Price, V, Forty, L, Fraser, C, Kogevinas, M, Frank, J, Streit, F, Strohmaier, J, Treutlein, J, Witt, S H, Kennedy, J L, Strauss, J S, Garnham, J, O'donovan, C, Slaney, C, Steinberg, S, Thorgeirsson, T E, Hautzinger, M, Steffens, M, Perlis, R H, Sánchez-Mora, C, Hipolito, M, Lawson, W B, Nwulia, E A, Levy, S E, Foroud, T M, Jamain, S, Young, A H, Mckay, J D, Albani, D, Zandi, P, Potash, J B, Zhang, P, Raymond Depaulo, J, Bergen, S E, Juréus, A, Karlsson, R, Kandaswamy, R, Mcguffin, P, Rivera, M, Lissowska, J, Cruceanu, C, Lucae, S, Cervantes, P, Budde, M, Gade, K, Heilbronner, U, Pedersen, M G, Morris, D W, Weickert, C S, Weickert, T W, Macintyre, D J, Lawrence, J, Elvsåshagen, T, Smeland, O B, Djurovic, S, Xi, S, Green, E K, Czerski, P M, Hauser, J, Xu, W, Vedder, H, Oruc, L, Spijker, A T, Gordon, S D, Medland, S E, Curtis, D, Mühleisen, T W, Badner, J, Scheftner, W A, Sigurdsson, E, Schork, N J, Schatzberg, A F, Bækvad-Hansen, M, Bybjerg-Grauholm, J, Hansen, C S, Knowles, J A, Szelinger, S, Montgomery, G W, Boks, M, Adolfsson, A N, Hoffmann, P, Bauer, M, Pfennig, A, Leber, M, Kittel-Schneider, S, Reif, A, Del-Favero, J, Fischer, S B, Herms, S, Reinbold, C S, Degenhardt, F, Koller, A C, Maaser, A, Ori, A, Dale, A M, Fan, C C, Greenwood, T A, Nievergelt, C M, Shehktman, T, Shilling, P D, Byerley, W, Bunney, W, Alliey-Rodriguez, N, Clarke, T K, Liu, C, Coryell, W, Akil, H, Burmeister, M, Flickinger, M, Li, J Z, Mcinnis, M G, Meng, F, Thompson, R C, Watson, S J, Zollner, S, Guan, W, Green, M J, Craig, D, Sobell, J L, Milani, L, Gordon-Smith, K, Knott, S V, Perry, A, Parra, J G, Mayoral, F, Rivas, F, Rice, J P, Barchas, J D, Børglum, A D, Mortensen, P B, Mors, O, Grigoroiu-Serbanescu, M, Bellivier, F, Etain, B, Leboyer, M, Ramos-Quiroga, J A, Agartz, I, Amin, F, Azevedo, M H, Bass, N, Black, D W, Blackwood, D H R, Bruggeman, R, Buccola, N G, Choudhury, K, Cloninger, C R, Corvin, A, Craddock, N, Daly, M J, Datta, S, Donohoe, G J, Duan, J, Dudbridge, F, Fanous, A, Freedman, R, Freimer, N B, Friedl, M, Gill, M, Gurling, H, De Haan, L, Hamshere, M L, Hartmann, A M, Holmans, P A, Kahn, R S, Keller, M C, Kenny, E, Kirov, G K, Krabbendam, L, Krasucki, R, Lencz, T, Levinson, D F, Lieberman, J A, Lin, D Y, Linszen, D H, Magnusson, P K E, Maier, W, Malhotra, A K, Mattheisen, M, Mattingsdal, M, Mccarroll, S A, Medeiros, H, Melle, I, Milanova, V, Myin-Germeys, I, Neale, B M, Ophoff, R A, Owen, M J, Pimm, J, Purcell, S M, Puri, V, Quested, D J, Rossin, L, Sanders, A R, Shi, J, Sklar, P, St Clair, D, Stroup, T S, Van Os, J, Wiersma, D & Zammit, S 2018, ' Improving genetic prediction by leveraging genetic correlations among human diseases and traits ', Nature Communications, vol. 9, no. 1, 02769-6 . https://doi.org/10.1038/s41467-017-02769-6
BASE-Bielefeld Academic Search Engine

Genomic prediction has the potential to contribute to precision medicine. However, to date, the utility of such predictors is limited due to low accuracy for most traits. Here theory and simulation study are used to demonstrate that widespread pleiot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153fe9353caeec532121eeecd713b381

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Using free flaps for reconstruction during infections by mucormycosis: A case report and a structured review of the literature

Autor: Reinbold, C., Derder, M., Hivelin, M., Ozil, C., Al Hindi, A., Lantieri, L.

Publikováno v: In Annales de chirurgie plastique esthétique April 2016 61(2):153-161

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.