Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Reinaldo B Geraldo"'
Autor:
Carlos JC Moreira, Peter J Waniek, Richard H Valente, Paulo C Carvalho, Jonas Perales, Denise Feder, Reinaldo B Geraldo, Helena C Castro, Patricia Azambuja, Norman A Ratcliffe, Cícero B Mello
Publikováno v:
Parasites & Vectors, Vol 7, Iss 1, Pp 1-16 (2014)
Abstract Background Chagas disease kills 2.5 thousand people per year of 15 million persons infected in Latin America. The disease is caused by the protozoan, Trypanosome cruzi, and vectored by triatomine insects, including Panstrongylus megistus, an
Externí odkaz:
https://doaj.org/article/5f8f5d950d834474855cdad727703a2e
Autor:
Evelize Folly, Renata Freire Alves Pereira, Helena Carla Castro, Fábio Aguiar-Alves, Reinaldo B Geraldo, Maria de Fátima Nogueira de Freitas Alves, Bruno Penna
Publikováno v:
Braz J Microbiol
MRSA infection and colonization have been reported in both companion and food-chain animals, highlighting MRSA as an important veterinary and zoonotic pathogen. Another mec allele, the mecC gene, also confers beta-lactam resistance in Staphylococcus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823650df5885a5d0f4ac745e3719bb60
https://pubmed.ncbi.nlm.nih.gov/33083945
https://pubmed.ncbi.nlm.nih.gov/33083945
Autor:
Mariana Severo Ramundo, Mariana Fernandes Carvalho, Alessandro K. Jordão, Helena Carla Castro, Juliana S. Novais, Vitor F. Ferreira, Agnes Marie Sá Figueiredo, Cristiana Ossaille Beltrame, Reinaldo B Geraldo
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Despite the existing antibiotics, antimicrobial resistance is a major challenge. Consequently, the development of new drugs remains in great demand. Quinones is part of a broad group of molecules that present antibacterial activity besides other biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb9f604afef828648677b4516bf8059
https://pubmed.ncbi.nlm.nih.gov/33184312
https://pubmed.ncbi.nlm.nih.gov/33184312
Autor:
Mara R.C. Couri, Marcos P. Silva, Ayla das Chagas Almeida, Lígia S. da Silveira, Vinícius R. D. Pereira, Josué de Moraes, Reinaldo B. Geraldo, Lara de Azevedo Alves, Priscila V. S. Z. Capriles, Ismael J. Alves Junior, Priscila de Faria Pinto, Ademar A. da Silva Filho, Maria Cecília Barbosa da Silveira Salvadori, Fernanda de Sá Teixeira, Pedro Luiz Silva Pinto, Elaine Soares Coimbra
Publikováno v:
Chemistry & Biodiversity.
In this study, we evaluated the in vitro and in vivo schistosomicidal activities of chalcones against Schistosoma mansoni worms. In vitro assays revealed that chalcones 1 and 3 were the most active compounds, without affecting significantly mammalian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d72c59a0a7ce7299d23ec3fda54da07
https://doi.org/10.1002/cbdv.201800398
https://doi.org/10.1002/cbdv.201800398
Autor:
A.L. Dos Santos, Norman A. Ratcliffe, Cicero B. Mello, João Pacheco, Paul Dyson, Reinaldo B Geraldo, A. Sibajev, Victor G O Evangelho, C.A.C. Araújo, P.J. Waniek, Patrícia Azambuja, Helena Carla Castro
Publikováno v:
Developmental & Comparative Immunology. 114:103823
Lectins are ubiquitous proteins involved in the immune defenses of different organisms and mainly responsible for non-self-recognition and agglutination reactions. This work describes molecular and biological characterization of a rhamnose-binding le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ad4286a90fe581c7d60631c2667030
https://doi.org/10.1016/j.dci.2020.103823
https://doi.org/10.1016/j.dci.2020.103823
Autor:
André Luiz Lourenço, Plínio Cunha Sathler, Reinaldo B Geraldo, Lucio Mendes Cabral, Helena Carla Castro, Pabulo Henrique Rampelotto, Max Seidy Saito
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 10, Pp 17901-17919 (2014)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fce6bdbedf5c983c2509221d30c9167
http://www.mdpi.com/1422-0067/15/10/17901
http://www.mdpi.com/1422-0067/15/10/17901
Autor:
Eleonora Kurtenbach, Russolina B. Zingali, Reinaldo B Geraldo, Victor David, Barbara Barbosa Succar, Rodolfo Mattos Albano, Fabio Ceneviva Lacerda Almeida, Luciana Wermelinger Serrão
Publikováno v:
Toxicon. 159:S29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8cb66e293ac6f52e8aacff48d7bb49b
https://doi.org/10.1016/j.toxicon.2018.11.417
https://doi.org/10.1016/j.toxicon.2018.11.417
Autor:
Lucio Mendes Cabral, Rita Martins, Reinaldo B Geraldo, Natália I.V. Loureiro, Carlos Rangel Rodrigues, Ruben dos Santos, Paula Alvarez Abreu, Helena Carla Castro
Publikováno v:
Journal of Molecular Recognition. 24:165-181
Proteases have received enormous interest from the research and medical communities because of their significant roles in several human diseases. Some examples include the involvement of thrombin in thrombosis, HIV-1 protease in Acquired Immune Defic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614b2e6fd54ec051319ac48fb6676a7f
https://doi.org/10.1002/jmr.1091
https://doi.org/10.1002/jmr.1091
Autor:
Luiza R.S. Dias, T Nagashima, Marcelo Braga dos Santos, Marcos da Veiga Kalil, Antonio C. C. Freitas, Carlos Rangel Rodrigues, Reinaldo B Geraldo, Magaly Girão Albuquerque, Murilo Lamim Bello, Lucio Mendes Cabral, Maria A.F. Vera, Helena Carla Castro, Paula Alvarez Abreu
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 17:730-739
Aim: Platelets plays a central role in hemostatic processes and consequently are similarly involved in pathological processes, such as arterial thrombosis and atherosclerosis. Herein we described the synthesis, antiplatelet profile and structure-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de230339aea966e6e09a083250c50d36
https://doi.org/10.5551/jat.3293
https://doi.org/10.5551/jat.3293
Autor:
Anna C. Cunha, Eduardo C.L. Carlos, Alessandro K. Jordão, Maria Cecília B. V. de Souza, Maria C.B. Almeida, Emerson Silva Lima, C. R. Rodrigues, Vitor F. Ferreira, Reinaldo B Geraldo, Helena Carla Castro
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:3713-3719
This paper describes the synthesis, antiplatelet and theoretical evaluations of 10 N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides (2a-j). These compounds were synthesized, characterized and screened for their in vitro antiplat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63dbd25990eeb3147bbe081ce6cdc206
https://doi.org/10.1016/j.bmc.2009.03.053
https://doi.org/10.1016/j.bmc.2009.03.053