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Akademický článek

Sequestration within peptide coacervates improves the fluorescence intensity, kinetics, and limits of detection of dye-based DNA biosensors

Autor: Christopher M. Green, Deborah Sementa, Divita Mathur, Joseph S. Melinger, Priyasha Deshpande, Shana Elbaum-Garfinkle, Igor L. Medintz, Rein V. Ulijn, Sebastián A. Díaz

Publikováno v: Communications Chemistry, Vol 7, Iss 1, Pp 1-9 (2024)

Abstract Peptide-based liquid-liquid phase separated domains, or coacervates, are a biomaterial gaining new interest due to their exciting potential in fields ranging from biosensing to drug delivery. In this study, we demonstrate that coacervates pr

Externí odkaz: https://doaj.org/article/17560a3af1604411ac2b319cd3bed36b

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Akademický článek

Cell-controlled dynamic surfaces for skeletal stem cell growth and differentiation

Autor: Hilary J. Anderson, Jugal Kishore Sahoo, Julia Wells, Sebastiaan van Nuffel, Hala S. Dhowre, Richard O. C. Oreffo, Mischa Zelzer, Rein V. Ulijn, Matthew J. Dalby

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Abstract Skeletal stem cells (SSCs, or mesenchymal stromal cells typically referred to as mesenchymal stem cells from the bone marrow) are a dynamic progenitor population that can enter quiescence, self-renew or differentiate depending on regenerativ

Externí odkaz: https://doaj.org/article/880f57ea76234d0e9bd8f308f8dbfe2f

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Akademický článek

Ten Steps to Organize a Virtual Scientific Symposium and Engage Your Global Audience

Autor: Jiye Son, Jasmine Sabio, Ankit Jain, Rein V. Ulijn

Publikováno v: Global Challenges, Vol 6, Iss 9, Pp n/a-n/a (2022)

Abstract The paper describes guidelines for the planning, organization, and successful execution of virtual, global scientific conferences for global audiences. The guidelines are based on experience and lessons learned during the organization of the

Externí odkaz: https://doaj.org/article/4c1e41e7bed84e66973b7f62f245fed5

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Akademický článek

Improving cartilage phenotype from differentiated pericytes in tunable peptide hydrogels

Autor: Enateri V. Alakpa, Vineetha Jayawarna, Karl E. V. Burgess, Christopher C. West, Bruno Péault, Rein V. Ulijn, Matthew J. Dalby

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

Abstract Differentiation of stem cells to chondrocytes in vitro usually results in a heterogeneous phenotype. This is evident in the often detected over expression of type X collagen which, in hyaline cartilage structure is not characteristic of the

Externí odkaz: https://doaj.org/article/95134f7e2eff4a20a241be0b0bcaf930

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Akademický článek

A Systematic Study on the Self-Assembly Behaviour of Multi Component Fmoc-Amino Acid-Poly(oxazoline) Systems

Autor: Pier-Francesco Caponi, Rein V. Ulijn

Publikováno v: Polymers, Vol 4, Iss 3, Pp 1399-1415 (2012)

We report a systematic study of a modular approach to create multi-component supramolecular nanostructures that can be tailored to be both enzyme and temperature responsive. Using a straightforward synthetic approach we functionalised a thermal respo

Externí odkaz: https://doaj.org/article/653b493a1244414191d345f0fe0cb4c6

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Akademický článek

Extracellular matrix formation in self-assembled minimalistic bioactive hydrogels based on aromatic peptide amphiphiles

Autor: Mi Zhou, Rein V Ulijn, Julie E Gough

Publikováno v: Journal of Tissue Engineering, Vol 5 (2014)

The hitherto inconsistency in clinical performance for engineered skin drives the current development of novel cell-scaffolding materials; one challenge is to only extract essential characteristics from the complex native ECM (extracellular matrix) a

Externí odkaz: https://doaj.org/article/89408b4ea6be41dba9c719ffaf652d5e

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