Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Rein Saral"'
Autor:
Rein Saral, Ronald J. Berenson, Shelly Heimfeld, Edward D. Ball, Richard E. Champlin, Kent Holland, Roy B. Jones, Elizabeth J. Shpall, Cindy Jacobs, C. Fred LeMaistre
Publikováno v:
Blood. 90:4313-4320
High-dose chemotherapy with hematopoietic progenitor cell support is administered increasingly to selected categories of patients with high-risk malignancies. Bone marrow and/or peripheral blood progenitor cells (PBPCs) are commonly cryopreserved wit
Autor:
Joseph H. Antin, Rein Saral, John R. Wingard, Rochelle M. Maher, Robert H. Collins, Joseph W. Fay, Daniel J. Weisdorf, Barbara E. Bierer, L. Pineiro, Donna Przepiorka, Bruce R. Blazar, William E. Fitzsimmons
Publikováno v:
Blood. 87:3514-3519
FK506 (Tacrolimus) is an immunosuppressive drug that blocks the activation of antigen-specific T lymphocytes, a major component in the pathogenesis of graft-versus-host disease (GVHD). This study was designed to obtain first estimates of the safety a
Autor:
Rein Saral, William H. Fleming, C. M. Baum, Aftab A. Ansari, H K Holland, T. F. Neal, John R. Wingard, Francois Villinger
Publikováno v:
Blood. 86:1749-1756
Controversy exists as to whether hematopoietic progenitor cells are infected by human immunodeficiency virus-1 (HIV-1) in vivo. Most studies have focused on patients with acquired immunodeficiency syndrome (AIDS)/AIDS-related complex, and little data
Autor:
Harold M. McClure, LA Myers, BK Kim, J. L. Orkin, Elizabeth Strobert, J Srinivasiah, R. B. Swenson, Rein Saral, Elliot F. Winton, Christopher D. Hillyer
Publikováno v:
Blood. 84:65-73
Using a recently developed hepsulfam-induced pancytopenia model in rhesus macaques, we have studied the effects of recombinant human interleukin-6 (rhIL-6) and rhIL-3 on marrow regeneration. Control animals were given hepsulfam (1.5 g/m2 by a single
Autor:
Rein Saral, William G. Merz, John R. Wingard, Michael G. Rinaldi, Thomas R. Johnson, Judith E. Karp
Publikováno v:
New England Journal of Medicine. 325:1274-1277
In early 1990 fluconazole was introduced as a prophylactic antifungal agent after bone marrow transplantation. During the same year Candida krusei emerged as the chief candida pathogen among patients with bone marrow transplants.To determine whether
Autor:
John R. Wingard, Rein Saral, Steven Piantadosi, L. Stefan Levin, Richard J. Jones, George W. Santos, Carol S. Niehaus, Douglas E. Peterson
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology. 72:419-424
Oral mucositis and hepatic veno-occlusive disease (HVOD) are common complications after bone marrow transplantation (BMT). Forty-seven patients were prospectively examined for development of ulcerative oral mucositis (UOM) and HVOD after allogeneic B
Autor:
John R. Wingard, Georgia B. Vogelsang, Robert A. Avery, Douglas A. Jabs, Rein Saral, George W. Santos
Publikováno v:
Ophthalmology. 98:1294-1301
Bone marrow transplantation has become widely used in the treatment of aplastic anemia and leukemia. Cyclosporine is used as prophylaxis against graft-versus-host disease. The authors report on eight cases of optic disc edema in patients taking cyclo
Autor:
Rein Saral, Steven Piantadosi, William H. Bums, John R. Wingard, George W. Santos, Marianna Zahurak
Publikováno v:
Clinical Infectious Diseases. 12:S793-S804
Cytomegalovirus (CMV) infections were studied in 785 bone marrow transplant recipients given intensive cytoreductive therapy. CMV excretion occurred in 24%, viremia in 9%, seroconversion in 40%, and overall active infection in 47%. CMV disease was mu
Autor:
Scott D. Rowley, Evan R. Farmer, John E. Wagner, J. M. Davis, S. J. Noga, Georgia B. Vogelsang, Barbara A. Zehnbauer, Albert D. Donnenberg, Rein Saral, George W. Santos
Publikováno v:
Blood. 75:1370-1377
In an attempt to reduce the incidence and severity of acute graft- versus-host disease (GVHD), we have decreased the number of bone marrow (BM) lymphocytes in the donor marrow graft before bone marrow transplantation (BMT) using counterflow centrifug
Autor:
Michael G. Rinaldi, William G. Merz, John R. Wingard, Judith E. Karp, Carole B. Miller, Rein Saral
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:1847-1849
Because the use of fluconazole prophylaxis had been associated with an increased rate of Candida krusei infections at The John Hopkins Oncology Center, early empiric amphotericin B plus flucytosine were given to febrile neutropenic patients colonized