Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes

Autor: Steven Blinka, Michael H. Reimer Jr., Kirthi Pulakanti, Sridhar Rao

Publikováno v: Cell Reports, Vol 17, Iss 1, Pp 19-28 (2016)

Super-enhancers are tissue-specific cis-regulatory elements that drive expression of genes associated with cell identity and malignancy. A cardinal feature of super-enhancers is that they are transcribed to produce enhancer-derived RNAs (eRNAs). It r

Externí odkaz: https://doaj.org/article/6b67709b046548c2968add763d47fe6d

Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin.

Autor: Murthy, Tushar¹, Bluemn, Theresa^2,3, Gupta, Abhishek K.⁴, Reimer, Jr., Michael^2,3, Rao, Sridhar^2,3, Pillai, Manoj M.⁴ manoj.pillai@yale.edu, Minella, Alex C.³ aminella@me.com

Publikováno v: Journal of Biological Chemistry. 6/29/2018, Vol. 293 Issue 26, p10220-10234. 15p. 1 Chart, 5 Graphs.

Strategy maps: Generalised giving-up densities for optimal foraging.

Autor: Arehart E; Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Reimer JR; Department of Mathematics and School of Biological Sciences, University of Utah, Salt Lake City, Utah, USA., Adler FR; Department of Mathematics and School of Biological Sciences, University of Utah, Salt Lake City, Utah, USA.

Publikováno v: Ecology letters [Ecol Lett] 2023 Mar; Vol. 26 (3), pp. 398-410. Date of Electronic Publication: 2023 Jan 31.

The Effects of Using a Clinical Prediction Rule to Prioritize Diagnostic Testing on Transmission and Hospital Burden: A Modeling Example of Early Severe Acute Respiratory Syndrome Coronavirus 2.

Autor: Reimer JR; Department of Mathematics, University of Utah, Salt Lake City, Utah, USA., Ahmed SM; Department of Internal Medicine, Division of Infectious Diseases, University of Utah School of Medicine, Salt Lake City Utah, USA., Brintz BJ; Department of Internal Medicine, Division of Infectious Diseases, University of Utah School of Medicine, Salt Lake City Utah, USA.; Department of Internal Medicine, Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah, USA., Shah RU; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City Utah, USA., Keegan LT; Department of Internal Medicine, Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah, USA., Ferrari MJ; Department of Biology, The Pennsylvania State University, State College, Pennsylvania, USA., Leung DT; Department of Internal Medicine, Division of Infectious Diseases, University of Utah School of Medicine, Salt Lake City Utah, USA.

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2021 Nov 16; Vol. 73 (10), pp. 1822-1830.

DOT1L inhibitors block abnormal self-renewal induced by cohesin loss.

Autor: Heimbruch KE; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA., Fisher JB; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Natural Sciences, Concordia University Wisconsin, Mequon, WI, USA., Stelloh CT; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA., Phillips E; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA., Reimer MH Jr; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA., Wargolet AJ; Department of Natural Sciences, Concordia University Wisconsin, Mequon, WI, USA., Meyer AE; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA., Pulakanti K; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA., Viny AD; Department of Medicine, Division of Hematology and Oncology, and Department of Genetics & Development, Columbia University Irving Medical Center, New York, NY, USA., Loppnow JJ; Department of Natural Sciences, Concordia University Wisconsin, Mequon, WI, USA., Levine RL; Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Department of Pathology, Molecular Cytology Core Facility, and Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pulikkan JA; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA., Zhu N; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA.; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA., Rao S; Blood Research Institute, Versiti, 8727 West Watertown Plank Road, Milwaukee, WI, 53226, USA. sridhar.rao@versiti.org.; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA. sridhar.rao@versiti.org.; Department of Pediatrics, Division of Hematology, Oncology, and Bone Marrow Transplantation, Medical College of Wisconsin, Milwaukee, WI, USA. sridhar.rao@versiti.org.

Publikováno v: Scientific reports [Sci Rep] 2021 Mar 31; Vol. 11 (1), pp. 7288. Date of Electronic Publication: 2021 Mar 31.