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Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques.

Autor: Sankhala RS; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Lal KG; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Jensen JL; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Dussupt V; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Mendez-Rivera L; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Bai H; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Wieczorek L; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Mayer SV; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Zemil M; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Wagner DA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Townsley SM; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Hajduczki A; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Chang WC; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Chen WH; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Donofrio GC; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Jian N; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., King HAD; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Lorang CG; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Martinez EJ; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Rees PA; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Peterson CE; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Schmidt F; Laboratory of Retrovirology, The Rockefeller University, New York, NY, USA., Hart TJ; Trudeau Institute, Saranac Lake, NY, USA., Duso DK; Trudeau Institute, Saranac Lake, NY, USA., Kummer LW; Trudeau Institute, Saranac Lake, NY, USA., Casey SP; Trudeau Institute, Saranac Lake, NY, USA., Williams JK; Integral Molecular, Philadelphia, PA, USA., Kannan S; Integral Molecular, Philadelphia, PA, USA., Slike BM; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Smith L; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Swafford I; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Thomas PV; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Tran U; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Currier JR; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Bolton DL; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Davidson E; Integral Molecular, Philadelphia, PA, USA., Doranz BJ; Integral Molecular, Philadelphia, PA, USA., Hatziioannou T; Laboratory of Retrovirology, The Rockefeller University, New York, NY, USA., Bieniasz PD; Laboratory of Retrovirology, The Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA., Paquin-Proulx D; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Reiley WW; Trudeau Institute, Saranac Lake, NY, USA., Rolland M; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Sullivan NJ; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Vasan S; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Collins ND; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Modjarrad K; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Vaccine Research and Development, Pfizer, Pearl River, New York, NY, USA., Gromowski GD; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Polonis VR; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Michael NL; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Krebs SJ; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA. skrebs@hivresearch.org.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA. skrebs@hivresearch.org., Joyce MG; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA. gjoyce@eidresearch.org.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA. gjoyce@eidresearch.org.

Publikováno v: Nature communications [Nat Commun] 2024 Jan 03; Vol. 15 (1), pp. 200. Date of Electronic Publication: 2024 Jan 03.

An allosteric inhibitor of sirtuin 2 deacetylase activity exhibits broad-spectrum antiviral activity.

Autor: Roche KL; Evrys Bio LLC, Pennsylvania Biotechnology Center, Doylestown, Pennsylvania, USA., Remiszewski S; Evrys Bio LLC, Pennsylvania Biotechnology Center, Doylestown, Pennsylvania, USA., Todd MJ; Evrys Bio LLC, Pennsylvania Biotechnology Center, Doylestown, Pennsylvania, USA., Kulp JL 3rd; Evrys Bio LLC, Pennsylvania Biotechnology Center, Doylestown, Pennsylvania, USA., Tang L; Evrys Bio LLC, Pennsylvania Biotechnology Center, Doylestown, Pennsylvania, USA., Welsh AV; Evrys Bio LLC, Pennsylvania Biotechnology Center, Doylestown, Pennsylvania, USA., Barry AP; Department of Molecular Genetics and Microbiology, Duke Center for Virology, Duke University School of Medicine, Durham, North Carolina, USA., De C; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, USA., Reiley WW; TICRO Bioservices, Trudeau Institute, Saranac Lake, New York, USA., Wahl A; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, USA., Garcia JV; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, USA., Luftig MA; Department of Molecular Genetics and Microbiology, Duke Center for Virology, Duke University School of Medicine, Durham, North Carolina, USA., Shenk T; Evrys Bio LLC, Pennsylvania Biotechnology Center, Doylestown, Pennsylvania, USA.; Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA., Tonra JR; Evrys Bio LLC, Pennsylvania Biotechnology Center, Doylestown, Pennsylvania, USA., Murphy EA; Evrys Bio LLC, Pennsylvania Biotechnology Center, Doylestown, Pennsylvania, USA.; Microbiology and Immunology Department, SUNY Upstate Medical University, Syracuse, New York, USA., Chiang LW; Evrys Bio LLC, Pennsylvania Biotechnology Center, Doylestown, Pennsylvania, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2023 Jun 15; Vol. 133 (12). Date of Electronic Publication: 2023 Jun 15.

SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity.

Autor: Joyce MG; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA. Electronic address: gjoyce@eidresearch.org., Chen WH; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Sankhala RS; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Hajduczki A; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Thomas PV; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Choe M; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Martinez EJ; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Chang WC; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Peterson CE; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Morrison EB; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Smith C; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Chen RE; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA., Ahmed A; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Wieczorek L; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Anderson A; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Oak Ridge Institute of Science and Education, Oak Ridge, TN, USA., Case JB; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA., Li Y; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Oertel T; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Oak Ridge Institute of Science and Education, Oak Ridge, TN, USA., Rosado L; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Ganesh A; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Oak Ridge Institute of Science and Education, Oak Ridge, TN, USA., Whalen C; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Oak Ridge Institute of Science and Education, Oak Ridge, TN, USA., Carmen JM; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Mendez-Rivera L; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Karch CP; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Gohain N; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Villar Z; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., McCurdy D; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Beck Z; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Kim J; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Shrivastava S; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Jobe O; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Dussupt V; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Molnar S; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Tran U; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Kannadka CB; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Soman S; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Kuklis C; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Zemil M; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Khanh H; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Wu W; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Cole MA; Trudeau Institute, Inc., Saranac Lake, NY, USA., Duso DK; Trudeau Institute, Inc., Saranac Lake, NY, USA., Kummer LW; Trudeau Institute, Inc., Saranac Lake, NY, USA., Lang TJ; Trudeau Institute, Inc., Saranac Lake, NY, USA., Muncil SE; Trudeau Institute, Inc., Saranac Lake, NY, USA., Currier JR; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Krebs SJ; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Polonis VR; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Rajan S; Antibody Discovery and Protein Engineering (ADPE), BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., McTamney PM; Microbial Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Esser MT; Microbial Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Reiley WW; Trudeau Institute, Inc., Saranac Lake, NY, USA., Rolland M; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., de Val N; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, MD, USA., Diamond MS; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA., Gromowski GD; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Matyas GR; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Rao M; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Michael NL; Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Modjarrad K; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA. Electronic address: kayvon.modjarrad.civ@mail.mil.

Publikováno v: Cell reports [Cell Rep] 2021 Dec 21; Vol. 37 (12), pp. 110143. Date of Electronic Publication: 2021 Dec 08.

Visualization of Resident Memory CD8 T Cells in the Lungs of Young and Aged Influenza Memory Mice and after Heterosubtypic Challenge.

Autor: Cookenham T; Trudeau Institute, Saranac Lake, NY; and., Lanzer KG; Trudeau Institute, Saranac Lake, NY; and., Tighe M; Trudeau Institute, Saranac Lake, NY; and., Ward JM; Global VetPathology, Montgomery Village, MD., Reiley WW; Trudeau Institute, Saranac Lake, NY; and wreiley@trudeauinstitute.org., Blackman MA; Trudeau Institute, Saranac Lake, NY; and wreiley@trudeauinstitute.org.

Publikováno v: ImmunoHorizons [Immunohorizons] 2021 Jul 15; Vol. 5 (7), pp. 543-556. Date of Electronic Publication: 2021 Jul 15.