Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Reiko Yutani"'
Autor:
Tomoyuki Furubayashi, Daisuke Inoue, Noriko Nishiyama, Akiko Tanaka, Reiko Yutani, Shunsuke Kimura, Hidemasa Katsumi, Akira Yamamoto, Toshiyasu Sakane
Publikováno v:
Pharmaceutics, Vol 12, Iss 1, p 79 (2020)
Recently, various types of cultured cells have been used to research the mechanisms of transport and metabolism of drugs. Although many studies using cultured cell systems have been published, a comparison of different cultured cell systems has never
Externí odkaz:
https://doaj.org/article/4f60b67f5cc64d0fa46c41ede7e3ddfb
Autor:
Reiko Yutani, Ryotaro Haku, Reiko Teraoka, Chisato Tode, Tatsuo Koide, Shuji Kitagawa, Toshiyasu Sakane, Toshiro Fukami
Publikováno v:
Crystals, Vol 9, Iss 11, p 553 (2019)
Carbamazepine (CBZ), a widely used antiepileptic, is known to be sensitive to light. The aim of this study was to evaluate the photostabilities of three cocrystals of CBZ (CBZ−succinic acid (SUC), CBZ−saccharin (SAC) form I, and CBZ−SAC form II
Externí odkaz:
https://doaj.org/article/bf811e433c904f7fbec58a4bf409de0c
Autor:
Haruhisa Ueda, Reiko Yutani, Chisato Tode, Takayuki Furuishi, Shuji Kitagawa, Reiko Teraoka, Toshiyasu Sakane, Hiromasa Nagase, Toshiro Fukami
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:940-944
The photostability of three types of furosemide (FUR) cocrystal (FUR-caffeine, FUR-urea, and FUR-nicotinamide cocrystals) was studied under irradiation with a D65 fluorescent lamp. The coloration of the FUR-urea pellets was significantly faster than
Autor:
Shiori Sakata, Shunsuke Kimura, Katsumi Iga, Reiko Yutani, Daisuke Inoue, Akiko Tanaka, Akiko Kiriyama, Akira Yamamoto, Hidemasa Katsumi, Erika Nishimura, Tomoyuki Furubayashi, Toshiyasu Sakane, Kosuke Kusamori
Publikováno v:
Biological and Pharmaceutical Bulletin. 41:1769-1777
We reported a novel transport mechanism of curcumin, independent of improved solubility, which involved direct contact of amorphous solid particles with the cell membrane. This mechanism has potential as a novel systemic delivery system of poorly wat
Autor:
Shunsuke Kimura, Akiko Tanaka, Toshiyasu Sakane, Kazutaka Higaki, Hidemasa Katsumi, Daisuke Inoue, Akiko Kiriyama, Reiko Yutani, Akira Yamamoto, Ken Ichi Ogawara, Tomoyuki Furubayashi
Publikováno v:
Molecular Pharmaceutics. 15:4462-4469
Nasal drug delivery has attracted significant attention as an alternative route to deliver drugs having poor bioavailability. Large-molecule drugs, such as peptides and central nervous system drugs, would benefit from intranasal delivery. Drug absorp
Autor:
Chikako Numata, Toshiyasu Sakane, Tomoka Shiono, Yoshiaki Okamoto, Mai Itoh, Reiko Teraoka, Reiko Yutani, Mizue Nakayama, Shuji Kitagawa, Midori Hirai, Mai Miyake
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 43:671-679
Publikováno v:
Results in Pharma Sciences
Most steroidal ointments contain propylene glycol (PG) and surfactants, which improve the solubility of corticosteroids in white petrolatum. Surfactants aid the uniform dispersal of PG within white petrolatum. Since the surfactants used in generic oi
Delivery of Oxytocin to the Brain for the Treatment of Autism Spectrum Disorder by Nasal Application
Autor:
Akiko Tanaka, Kosuke Kusamori, Hidemasa Katsumi, Akira Yamamoto, Mari Arai, Toshiyasu Sakane, Tomoyuki Furubayashi, Shunsuke Kimura, Reiko Yutani, Daisuke Inoue, Akiko Kiriyama
Publikováno v:
Molecular pharmaceutics. 15(3)
Oxytocin (OXT) is a cyclic nonapeptide, two amino acids of which are cysteine, forming an intramolecular disulfide bond. OXT is produced in the hypothalamus and is secreted into the bloodstream from the posterior pituitary. As recent studies have sug
Autor:
Akiko Kiriyama, Daisuke Inoue, Toshiyasu Sakane, Akiko Tanaka, Shunsuke Kimura, Kazutaka Higaki, Tomoyuki Furubayashi, Akira Yamamoto, Reiko Yutani, Hidemasa Katsumi, Toshikiro Kimura, Ken Ichi Ogawara
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 117
Drug absorption after nasal application is dependent on drug clearance from the nasal cavity, which is determined by nasal mucociliary clearance (MC). We previously developed an in vitro method to evaluate MC via the translocation velocity of fluores
Autor:
Masakazu Enomura, Daisuke Inoue, Akiko Kiriyama, Kosuke Kusamori, Akira Yamamoto, Toshiyasu Sakane, Mai Yoshizumi, Akiko Tanaka, Reiko Yutani, Katsumi Iga, Shunsuke Kimura, Kaeko Araki, Hidemasa Katsumi, Reiko Teraoka, Tomoyuki Furubayashi
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 122
Amorphization has been widely recognized as a useful solubilization technique for poorly water-soluble drugs, such as curcumin. We have recently reported the novel finding that the membrane transport of curcumin was markedly enhanced when amorphous s