Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Reiko J Tanaka"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 5, p e1012105 (2024)
Quantifying fungal growth underpins our ability to effectively treat severe fungal infections. Current methods quantify fungal growth rates from time-course morphology-specific data, such as hyphal length data. However, automated large-scale collecti
Externí odkaz:
https://doaj.org/article/959046aa6f9b4e11a69665bce9a14bbb
Autor:
Alejandro A Granados, Matthew M Crane, Luis F Montano-Gutierrez, Reiko J Tanaka, Margaritis Voliotis, Peter S Swain
Publikováno v:
eLife, Vol 6 (2017)
Improving in one aspect of a task can undermine performance in another, but how such opposing demands play out in single cells and impact on fitness is mostly unknown. Here we study budding yeast in dynamic environments of hyperosmotic stress and sho
Externí odkaz:
https://doaj.org/article/a9ccfd876af54dc98170e027b705accc
Autor:
Mariko Yokouchi, Toru Atsugi, Mark van Logtestijn, Reiko J Tanaka, Mayumi Kajimura, Makoto Suematsu, Mikio Furuse, Masayuki Amagai, Akiharu Kubo
Publikováno v:
eLife, Vol 5 (2016)
In multicellular organisms, cells adopt various shapes, from flattened sheets of endothelium to dendritic neurons, that allow the cells to function effectively. Here, we elucidated the unique shape of cells in the cornified stratified epithelia of th
Externí odkaz:
https://doaj.org/article/517aa6de09034e01bcb8847dbdcc8dc1
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117292 (2015)
The stratum corneum (SC) provides a permeability barrier that limits the inflow and outflow of water. The permeability barrier is continuously and dynamically formed, maintained, and degraded along the depth, from the bottom to the top, of the SC. Na
Externí odkaz:
https://doaj.org/article/96e92dea94dc4050bde6eb1b3b204681
Publikováno v:
Frontiers in Neural Circuits, Vol 7 (2013)
Due to methodological limitations neural function is mostly studied under open-loop conditions. Normally, however, nervous systems operate in closed-loop where sensory input is processed to generate behavioural outputs, which again change the sensory
Externí odkaz:
https://doaj.org/article/2c0860ef1378439eb1d80a3488b36946
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53544 (2013)
The understanding of pathological processes is based on the comparison between physiological and pathological conditions, and transcriptomic analysis has been extensively applied to various diseases for this purpose. However, the way in which the tra
Externí odkaz:
https://doaj.org/article/a48a70d09a42459d89de4e163633795f
Autor:
David Schley, Reiko J Tanaka, Kritsada Leungchavaphongse, Vahid Shahrezaei, John Ward, Clare Grant, Bryan Charleston, Christopher J Rhodes
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30435 (2012)
Foot and mouth disease virus causes a livestock disease of significant global socio-economic importance. Advances in its control and eradication depend critically on improvements in vaccine efficacy, which can be best achieved by better understanding
Externí odkaz:
https://doaj.org/article/fef0c41b689142deaa036c5ed124339f
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19895 (2011)
Atopic dermatitis (AD) is a widely spread cutaneous chronic disease characterised by sensitive reactions (eg. eczema) to normally innocuous elements. Although relatively little is understood about its underlying mechanisms due to its complexity, skin
Externí odkaz:
https://doaj.org/article/e94c417881694e44988eaa1e72a8c13c
Publikováno v:
Allergy. 77:582-594
BackgroundSeveral biologics for atopic dermatitis (AD) have demonstrated good efficacy in clinical trials, but with a substantial proportion of patients being identified as poor responders. This study aims to understand the pathophysiological backgro
Autor:
Guillem Hurault, S. Ljubojevic Hadzavdic, Reiko J. Tanaka, Branka Marinović, B. Pavicic, K. Zuzul, Sanja Kezic, Y. Sun, Ivone Jakasa, Marija Petković, Anamaria Balić, R. Jurakić Tončić
Publikováno v:
Journal of the European Academy of Dermatology and Venereology, 35(5), 1186-1196. Wiley-Blackwell
Background Atopic dermatitis (AD) presents with the wide spectrum of clinical phenotypes within and between various populations. Recent study showed low frequency of filaggrin loss-of-function (FLG LOF) mutations in Croatian AD patients. At present,