Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Reiko Akitake"'
Autor:
Hideyuki Komekado, Makoto Kunichika, Takeshi Kimura, Keitaro Kanda, Kenji Kawada, Shoko Ishizu, Kyoichi Matsumoto, Mikiko Ohno, Yoshiharu Sakai, Reiko Akitake-Kawano, Eiichiro Nishi, Masato Nakatsuji, Hiroshi Seno, Mayumi Kawada, Tateo Sawabu, Yoshinori Hiraoka, Tsutomu Chiba, Yuki Nakanishi
Publikováno v:
EMBO Molecular Medicine
Nardilysin (NRDc), a metalloendopeptidase of the M16 family, promotes ectodomain shedding of the precursor forms of various growth factors and cytokines by enhancing the protease activities of ADAM proteins. Here, we show the growth-promoting role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e265a55b68c5a2949d266d4c7a80a9
https://doi.org/10.1002/emmm.201200216
https://doi.org/10.1002/emmm.201200216
Autor:
Hiroshi Seno, Kenji Kawada, Mayumi Kawada, Hideyuki Komekado, Yuki Nakanishi, Keitaro Kanda, Yoshiharu Sakai, Tsutomu Chiba, Reiko Akitake, Emiko Mizoguchi
Publikováno v:
Oncogene
Chitinase 3-like 1 (CHI3L1), one of the mammalian members of the chitinase family, is expressed in several types of human cancer, and elevated serum level of CHI3L1 is suggested to be a biomarker of poor prognosis in advanced cancer patients. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d0885c212fbdc75306bfa6c19e04f1
https://doi.org/10.1038/onc.2011.498
https://doi.org/10.1038/onc.2011.498
Autor:
Keitaro Kanda, Hiroshi Seno, Mayumi Kawada, Shoko Ishizu, Yuki Nakanishi, Hideyuki Komekado, Tsutomu Chiba, Taro Ueo, Manabu Minami, Reiko Akitake-Kawano, Masato Nakatsuji
Publikováno v:
Carcinogenesis. 32:1333-1339
Macrophages are a major component of tumor stroma. Tumor-associated macrophages (TAMs) show anti- (M1) or protumor (M2) functions depending on the cytokine milieu of the tumor microenvironment. Cyclooxygenase-2 (COX-2) is constitutively expressed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cceac69ba2d519f8437f65f9a7d75d31
https://doi.org/10.1093/carcin/bgr128
https://doi.org/10.1093/carcin/bgr128
Publikováno v:
Digestive diseases and sciences. 55(6):1781-1784
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4157d36818c9908758e0303589faa9
http://hdl.handle.net/2433/126698
http://hdl.handle.net/2433/126698
Autor:
Hiroshi Seno, Mayumi Kawada, Yuto Kimura, Yoshiharu Sakai, Tsutomu Chiba, Keitaro Kanda, Takuto Yoshioka, Masato Nakatsuji, Kenji Kawada, Reiko Akitake-Kawano, Yuki Nakanishi
Publikováno v:
Carcinogenesis. 34(7)
Growth arrest-specific gene (Gas) 6 is a γ-carboxyglutamic acid domain-containing protein, which shares 43% amino acid identity with protein S. Gas6 has been shown to enhance cancer cell proliferation in vitro. On the other hand, recent studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b22c3c5b19b03e019eb10f08bbd1f5c
https://pubmed.ncbi.nlm.nih.gov/23430954
https://pubmed.ncbi.nlm.nih.gov/23430954
Autor:
Tsutomu Chiba, Tomohiro Watanabe, Norimitsu Uza, Chikage Zaima, Hiroshi Ida, Naoshi Nishida, Shinsuke Tada, Reiko Akitake
Publikováno v:
Gut. 59(4)
We report a case of immunoglobulin G4 (IgG4)-related sclerosing disease involving the pancreas, liver and salivary glands. Massive infiltration of IgG4-expressing plasma cells was seen in the liver and submandibular lymph nodes. Interestingly, accumu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba11ad35fc4f06e9e56284a5b8faadd0
https://pubmed.ncbi.nlm.nih.gov/20332525
https://pubmed.ncbi.nlm.nih.gov/20332525
Autor:
Reiko Akitake, Tsutomu Chiba, Hideki Nakamura, Hiroshi Seno, Hiroyuki Kimura, Satoru Sekoguchi, Sotaro Fujimoto
Publikováno v:
Internal medicine (Tokyo, Japan). 48(24)
Perivascular epithelioid cell (PEC) is a unique cell which expresses both myogenic and melanocytic markers, and forms PEComa. A 36-year-old woman presented with a 35 mm-diameter liver tumor. MRI showed poor fat component in the tumor. Contrast-enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d8ce5a6a9e7f99292295ece61a25bb
https://pubmed.ncbi.nlm.nih.gov/20009396
https://pubmed.ncbi.nlm.nih.gov/20009396
Autor:
Satoru Ueno, Shin'ichi Miyamoto, Tsutomu Chiba, Hiroshi Nakase, Noriyuki Iehara, Reiko Akitake
Publikováno v:
Digestion. 80(3)
We present the case of a patient with lupus enteritis accompanied by both lupus cystitis and lupus nephritis without a history of systemic lupus erythematosus. The patient had a 2-month history of diarrhea and pollakiuria and was admitted to our hosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca06270d2bb4a50d5102a469b6d00053
https://pubmed.ncbi.nlm.nih.gov/19776578
https://pubmed.ncbi.nlm.nih.gov/19776578
Autor:
Yasuyuki, Gen, Hiroyuki, Kimura, Reiko, Akitake, Aya, Sakai, Akifumi, Fukui, Toshitatsu, Takao, Satoshi, Ikezawa, Atsuhiro, Masuda, Hidetaka, Takashima, Eiji, Funatsu, Hideki, Nakamura, Yusuke, Okuyama, Masahiro, Arai, Nobuaki, Yagi, Hiromu, Kutsumi, Sotaro, Fujimoto, Yoshito, Takeuchi
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 33(4)
A 72-year-old man with type C liver cirrhosis had suffered from hepatocellular carcinoma (HCC) since April, 2001. HCC spread diffusely all over the right lobe of his liver, and the serum alpha-fetoprotein (AFP) value increased up to 42,696 ng/ml in J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a5fd2468604fbb00ac7b469a6ed04d0
https://pubmed.ncbi.nlm.nih.gov/16612162
https://pubmed.ncbi.nlm.nih.gov/16612162
Autor:
Kazuo Ono, Yasunobu Yamashita, Keitaro Kanda, T. Kayahara, Tsutomu Chiba, Reiko Akitake, Yuki Nakanishi, Hiroshi Seno
Publikováno v:
Endoscopy. 42:E37-E38
hospital because of hematemesis. Esophagogastroduodenoscopy showed more than 10 gastric polypoid lesions (●" Fig. 1 a). The smaller lesions were sessile, clearly demarcated, and had whitish erosions on the surface (●" Fig. 1b). The larger lesions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f89021bee66f7815fa2b12851ce560
https://doi.org/10.1055/s-0029-1215263
https://doi.org/10.1055/s-0029-1215263