Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Reijiro Arakawa"'
Autor:
Tomohiro Otsuka, Tomomi Masuda, Yuji Takahashi, Ayako Suzuki, Akiyoshi Uemura, Reijiro Arakawa, Takeshi Okabe, Akira Naito
Publikováno v:
Journal of Pharmacological Sciences, Vol 151, Iss 1, Pp 28-36 (2023)
Triamcinolone acetonide (TA) has been shown to improve morphological and functional outcome in diabetic macular edema (DME) patients. However, the functional mechanism of TA has not been elucidated yet. In this study we investigated the detailed func
Externí odkaz:
https://doaj.org/article/914175200b2e46749768f9ea4e2ff87e
Autor:
Yuko Arie, Hiroko Miyai, Ayako Suzuki, Takeshi Okabe, Mitsuyo Takashima, Mayumi Takata, Takashi Kurasawa, Masaki Ito, Reijiro Arakawa, Yuichiro Ogura, Akira Naito
Publikováno v:
International Journal of Ophthalmology, Vol 13, Iss 12, Pp 1864-1871 (2020)
AIM: To compare the differences in kinetics, distribution, and toxicity of triamcinolone acetonide (TA) between the injection methods, sub-Tenon and intravitreal injections in rabbit ocular tissues. METHODS: TA was injected into the vitreous or the
Externí odkaz:
https://doaj.org/article/59e6ec1271b14d8988b71d9deaa08487
Autor:
Reijiro Arakawa, Maki Tsujita, Noriyuki Iwamoto, Chisato Ito-Ohsumi, Rui Lu, Chen-Ai Wu, Kenji Shimizu, Tomoji Aotsuka, Hashime Kanazawa, Sumiko Abe-Dohmae, Shinji Yokoyama
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 11, Pp 2299-2305 (2009)
Expression of ABCA1 is regulated by transcription of the gene and calpain-mediated proteolytic degradation, and inhibition ABCA1 degradation results in increased ABCA1 and HDL biogenesis in vitro. We examined whether this approach could be a potentia
Externí odkaz:
https://doaj.org/article/415a88b6266446ba96496659638748a6
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 12, Pp 1952-1962 (2000)
High density lipoprotein (HDL) is assembled by interaction of apolipoprotein A-I with human monocytic leukemia cell line THP-1 by removing cellular cholesterol and phospholipid. Although the HDL formed with undifferentiated THP-1 cells contained only
Externí odkaz:
https://doaj.org/article/4308727105664e709914420e35deca88
Autor:
Tomohiro Otsuka, Tomomi Masuda, Yuji Takahashi, Ayako Suzuki, Akiyoshi Uemura, Reijiro Arakawa, Takeshi Okabe, Akira Naito
Publikováno v:
Journal of pharmacological sciences. 151(1)
Triamcinolone acetonide (TA) has been shown to improve morphological and functional outcome in diabetic macular edema (DME) patients. However, the functional mechanism of TA has not been elucidated yet. In this study we investigated the detailed func
Autor:
Yuichiro Ogura, Ayako Suzuki, Masaki Ito, Mitsuyo Takashima, Takeshi Okabe, Reijiro Arakawa, Takashi Kurasawa, Mayumi Takata, Akira Naito, Hiroko Miyai, Yuko Arie
Publikováno v:
International Journal of Ophthalmology, Vol 13, Iss 12, Pp 1864-1871 (2020)
Int J Ophthalmol
Int J Ophthalmol
AIM: To compare the differences in kinetics, distribution, and toxicity of triamcinolone acetonide (TA) between the injection methods, sub-Tenon and intravitreal injections in rabbit ocular tissues. METHODS: TA was injected into the vitreous or the s
Autor:
Rui Lu, Noriyuki Iwamoto, Maki Tsujita, Sumiko Abe-Dohmae, Reijiro Arakawa, Shinji Yokoyama, Cheng-Ai Wu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1821:547-551
Helical apolipoproteins remove cellular phospholipid and cholesterol to generate nascent HDL and this reaction is the major source of plasma HDL. ABCA1 is mandatory and rate-limiting for this reaction. Besides regulation of the gene expression by tra
Autor:
Tomoji Aotsuka, Shinji Yokoyama, Maki Tsujita, Chen-Ai Wu, Noriyuki Iwamoto, Sumiko Abe-Dohmae, Reijiro Arakawa, Rui Lu, Hashime Kanazawa, Shimizu Kenji, Chisato Ito-Ohsumi
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 11, Pp 2299-2305 (2009)
Expression of ABCA1 is regulated by transcription of the gene and calpain-mediated proteolytic degradation, and inhibition ABCA1 degradation results in increased ABCA1 and HDL biogenesis in vitro. We examined whether this approach could be a potentia
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 25:1193-1197
Objective— Fibrates are widely used drugs to reduce plasma triglyceride and increase high-density lipoprotein. Their active forms, fibric acids, are peroxisome proliferator-activated receptor-α activators, but no direct evidence has been demonstra
Autor:
Kazumitsu Ueda, Arowu R. Tanaka, Shogo Suzuki, Kazuhide Inoue, Reijiro Arakawa, Shinji Yokoyama, Sumiko Abe-Dohmae, Norimasa Tamehiro, Tomoko Nishimaki-Mogami
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 24:519-525
Objective—Release of cellular cholesterol and phospholipid mediated by helical apolipoprotein and ATP-binding cassette transporter (ABC) A1 is a major source of plasma HDL. We investigated the effect of calcium channel blockers on this reaction.Met