Gut microbiome in endometriosis: a cohort study on 1000 individuals

Autor: Inmaculada Pérez-Prieto, Eva Vargas, Eduardo Salas-Espejo, Kreete Lüll, Analuce Canha-Gouveia, Laura Antequera Pérez, Juan Fontes, Andres Salumets, Reidar Andreson, Oliver Aasmets, Estonian Biobank research team, Katrine Whiteson, Elin Org, Signe Altmäe

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)

Abstract Background Endometriosis, defined as the presence of endometrial-like tissue outside of the uterus, is one of the most prevalent gynecological disorders. Although different theories have been proposed, its pathogenesis is not clear. Novel st

Externí odkaz: https://doaj.org/article/9d6779a7eeef4f9d971a0829ce693ad9

A history of repeated antibiotic usage leads to microbiota-dependent mucus defects

Autor: Kertu Liis Krigul, Rachel H. Feeney, Supapit Wongkuna, Oliver Aasmets, Sandra M. Holmberg, Reidar Andreson, Fabiola Puértolas-Balint, Kateryna Pantiukh, Linda Sootak, Tõnis Org, Tanel Tenson, Elin Org, Bjoern O. Schroeder

Publikováno v: Gut Microbes, Vol 16, Iss 1 (2024)

Recent evidence indicates that repeated antibiotic usage lowers microbial diversity and ultimately changes the gut microbiota community. However, the physiological effects of repeated – but not recent – antibiotic usage on microbiota-mediated muc

Externí odkaz: https://doaj.org/article/6ab32d2d594c47a0be3181f461dbb206

Genome-wide histone modification profiling of inner cell mass and trophectoderm of bovine blastocysts by RAT-ChIP.

Autor: Tõnis Org, Kati Hensen, Rita Kreevan, Elina Mark, Olav Sarv, Reidar Andreson, Ülle Jaakma, Andres Salumets, Ants Kurg

Publikováno v: PLoS ONE, Vol 14, Iss 11, p e0225801 (2019)

Chromatin immunoprecipitation coupled with next-generation sequencing (ChIP-seq) has revolutionized our understanding of chromatin-related biological processes. The method, however, requires thousands of cells and has therefore limited applications i

Externí odkaz: https://doaj.org/article/c06c968f555845d0bbef1e545ed2d3c7

The landscape of autosomal-recessive pathogenic variants in European populations reveals phenotype-specific effects

Autor: Han G. Brunner, Ephrat Levy-Lahad, Chris Tyler-Smith, Massimo Mezzavila, Christian Gilissen, Reedik Mägi, Andres Metspalu, Yali Xue, Reidar Andreson, Shai Carmi, Hila Fridman, Helger G. Yntema

Publikováno v: American Journal of Human Genetics, 108, 608-619
American Journal of Human Genetics, 108(4), 608-619. Cell Press
Am J Hum Genet
American Journal of Human Genetics, 108, 4, pp. 608-619

The number and distribution of recessive alleles in the population for various diseases are not known at genome-wide-scale. Based on 6447 exome-sequences of healthy, genetically-unrelated Europeans of two distinct ancestries, we estimate that every i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e334b350d75a8cfb4f615b5bac15f7
https://doi.org/10.1016/j.ajhg.2021.03.004

Genome-wide histone modification profiling of inner cell mass and trophectoderm of bovine blastocysts by RAT-ChIP

Autor: Olav Sarv, Andres Salumets, Reidar Andreson, Elina Mark, Ülle Jaakma, Tõnis Org, Rita Kreevan, Ants Kurg, Kati Hensen

Publikováno v: PLoS ONE
PLoS ONE, Vol 14, Iss 11, p e0225801 (2019)

Chromatin immunoprecipitation coupled with next-generation sequencing (ChIP-seq) has revolutionized our understanding of chromatin-related biological processes. The method, however, requires thousands of cells and has therefore limited applications i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141acb379f24554ff0fbe220ba47d77b
http://europepmc.org/articles/PMC6876874