A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver

Autor: Annie S. P. Yang, Carolina Barillas-Mury, Marlon Dillon, Rachel Vistein, Nicole Cavett, David Baker, Arne Schön, Monica W. Gerber, Robert W. Sauerwein, Reid B. Ballard, James O’Connor, Barbara J. Flynn, Alvaro Molina-Cruz, Jorgen Nelson, Fidel Zavala, Lawrence T. Wang, Robert A. Seder, Neville K. Kisalu, Amanda Fabra-García, Joseph R. Francica, Lais Pereira, Rogerio Amino, Bryan T. Mayer, Ian A. Cockburn, Neil P. King, Marie Pancera, Rosemarie D. Mason, Yevel Flores-Garcia, Raphael Gottardo, Azza H. Idris, Nicholas K. Hurlburt

Publikováno v: Immunity, 53, 733-744.e8
Immunity
Immunity, 2020, 53 (4), pp.733-744.e8. ⟨10.1016/j.immuni.2020.08.014⟩
Immunity, 53, 4, pp. 733-744.e8
Immunity, Elsevier, 2020, 53 (4), pp.733-744.e8. ⟨10.1016/j.immuni.2020.08.014⟩

International audience; Discovering potent human monoclonal antibodies (mAbs) targeting the Plasmodium falciparum circumsporozoite protein (PfCSP) on sporozoites (SPZ) and elucidating their mechanisms of neutralization will facilitate translation for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e2323b519a5419c4ded96d6aa53424
http://hdl.handle.net/2066/226211