Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Reid A. Brewer"'
Autor:
Steven Erwood, Onofrio Laselva, Teija M.I. Bily, Reid A. Brewer, Alexandra H. Rutherford, Christine E. Bear, Evgueni A. Ivakine
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 1118-1128 (2020)
Nonsense-mediated decay (NMD) is a major pathogenic mechanism underlying a diversity of genetic disorders. Nonsense variants tend to lead to more severe disease phenotypes and are often difficult targets for small molecule therapeutic development as
Externí odkaz:
https://doaj.org/article/eb2405ef414a48d59db42b474b399baf
Autor:
Reid A. Brewer, Teija M.I. Bily, Onofrio Laselva, Alexandra H. Rutherford, Evgueni A. Ivakine, Steven Erwood, Christine E. Bear
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 1118-1128 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 1118-1128 (2020)
Nonsense-mediated decay (NMD) is a major pathogenic mechanism underlying a diversity of genetic disorders. Nonsense variants tend to lead to more severe disease phenotypes and are often difficult targets for small molecule therapeutic development as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e80f83da4849f196a2a2866431d5b7
http://europepmc.org/articles/PMC7256445
http://europepmc.org/articles/PMC7256445
Autor:
Steven Erwood, Teija M. I. Bily, Jason Lequyer, Joyce Yan, Nitya Gulati, Reid A. Brewer, Liangchi Zhou, Laurence Pelletier, Evgueni A. Ivakine, Ronald D. Cohn
Publikováno v:
Nature biotechnology. 40(6)
High-throughput functional characterization of genetic variants in their endogenous locus has so far been possible only with methods that rely on homology-directed repair, which are limited by low editing efficiencies. Here, we adapted CRISPR prime e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55900ff40469dff252cc50103fff9bad
https://pubmed.ncbi.nlm.nih.gov/35578021
https://pubmed.ncbi.nlm.nih.gov/35578021
Autor:
Teija M.I. Bily, Ronald D. Cohn, Laurence Pelletier, Lequyer J, Yan J, Gulati N, Reid A. Brewer, Liangchi Zhou, Steven Erwood, Evgueni A. Ivakine
Over the last decade, next generation sequencing has become widely implemented in clinical practice. However, as genetic variants of uncertain significance (VUS) are frequently identified, the need for scaled functional interpretation of such variant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc404c94250b52a6d0168c1f3dde9b52
https://doi.org/10.1101/2021.05.11.443710
https://doi.org/10.1101/2021.05.11.443710
Autor:
Steven Erwood, Liangchi Zhou, Teija M.I. Bily, Eleonora Maino, Reid A. Brewer, Ronald D. Cohn, Evgueni A. Ivakine
Publikováno v:
Genome Res
The accurate clinical interpretation of human sequence variation is foundational to personalized medicine. This remains a pressing challenge, however, as genome sequencing becomes routine and new functionally undefined variants rapidly accumulate. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b963dd4b8a6edcac1ce3114faf4bfd91
https://europepmc.org/articles/PMC6886506/
https://europepmc.org/articles/PMC6886506/
Publikováno v:
Marine Biology Research. 13:909-918
Octopus growth and movement occurs during all life stages and have implications for survival, food web dynamics and reproduction. From 2009 to 2011, 1714 North Pacific giant octopus (Enteroctopus dofleini) were tagged and recaptured in the eastern Be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f30b6ae70b637fc2231f9b69069d31d4
https://doi.org/10.1080/17451000.2017.1309436
https://doi.org/10.1080/17451000.2017.1309436
Autor:
Reid S. Brewer, Andrew C. Seitz
Publikováno v:
Malacologia. 56:297-300
Life-history information regarding most cephalopod species is somewhat scarce, and information relating anatomical anomalies of cephalopods is even more limited. For octopus species, the few anomalies that have been reported include: arm bifurcations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d64dc3cb6b46f95c16c58f6a8c180f5
https://doi.org/10.4002/040.056.0216
https://doi.org/10.4002/040.056.0216
Autor:
Brenda L. Norcross, Reid S. Brewer
Publikováno v:
Fisheries Research. :17-20
Visible Implant Elastomer (VIE) tags represent a viable approach for long-term tracking of North Pacific giant octopus ( Enteroctopus dofleini ) in Alaska. Over a two year period, 1730 E. dofleini were tagged with individually identifiable VIE tags a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7812b14aa5a3e31decc992bc666b42c
https://doi.org/10.1016/j.fishres.2012.07.020
https://doi.org/10.1016/j.fishres.2012.07.020
Autor:
James P. Dines, Olga A. Filatova, Paul R. Wade, Alexander M. Burdin, Merel L. Dalebout, Michelle Ridgway, Phillip A. Morin, Morgane Lauf, Kelly M. Robertson, Gaëtan Richard, C. Scott Baker, Erich Hoyt, Reid S. Brewer, Jean-Luc Jung, Charles W. Potter, Ivan D. Fedutin
Publikováno v:
Marine Mammal Science
Marine Mammal Science, Wiley, 2016, 33 (1), pp.96-111. ⟨10.1111/mms.12345⟩
Marine Mammal Science, Wiley, 2016, 33 (1), pp.96-111. ⟨10.1111/mms.12345⟩
There are two recognized species in the genus Berardius, Baird’s and Arnoux’s beaked whales. In Japan, whalers have traditionally recognized two forms of Baird’s beaked whales, the common “slate-gray” form and a smaller, rare “black” fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6536879db4c8219bd6a37dcce525b869
https://hal.archives-ouvertes.fr/hal-01363951
https://hal.archives-ouvertes.fr/hal-01363951
Autor:
Brenda Konar, Reid S. Brewer
Publikováno v:
Marine Biology. 147:789-795
Chemical cues released by damaged or dead organisms can affect how and where benthic organisms feed. These cues may cause predators to act as opportunistic scavengers in lieu of their normal predatory role. A scavenger, as defined in this study, is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5822381eeea5bd8fcecb733d5a57cf9
https://doi.org/10.1007/s00227-005-1608-7
https://doi.org/10.1007/s00227-005-1608-7