Longitudinal Evaluation of Hyper-Reflective Foci in the Retina Following Subretinal Delivery of Adeno-Associated Virus in Non-Human Primates.

Autor: Rodríguez-Bocanegra E; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany., Wozar F; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany., Seitz IP; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany., Reichel FFL; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany., Ochakovski A; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany., Bucher K; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany., Wilhelm B; STZ Eye Trial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany., Bartz-Schmidt KU; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany., Peters T; STZ Eye Trial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany., Fischer MD; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; STZ Eye Trial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Oxford Eye Hospital, Oxford University NHS Foundation Trust, Oxford, UK.; Nuffield Laboratory of Ophthalmology, Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

Publikováno v: Translational vision science & technology [Transl Vis Sci Technol] 2021 May 03; Vol. 10 (6), pp. 15.

Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients With Choroideremia: A Randomized Clinical Trial.

Autor: Fischer MD; University Eye Hospital, University of Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany.; STZ eyetrial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Tübingen, Germany.; Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, United Kingdom., Ochakovski GA; University Eye Hospital, University of Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Beier B; STZ eyetrial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Tübingen, Germany., Seitz IP; University Eye Hospital, University of Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Vaheb Y; University Eye Hospital, University of Tübingen, Tübingen, Germany., Kortuem C; University Eye Hospital, University of Tübingen, Tübingen, Germany., Reichel FFL; University Eye Hospital, University of Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Kuehlewein L; University Eye Hospital, University of Tübingen, Tübingen, Germany., Kahle NA; STZ eyetrial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Tübingen, Germany., Peters T; STZ eyetrial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Tübingen, Germany., Girach A; Nightstar Therapeutics, London, United Kingdom., Zrenner E; University Eye Hospital, University of Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., Ueffing M; Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany., MacLaren RE; Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, United Kingdom.; Nightstar Therapeutics, London, United Kingdom.; Oxford Eye Hospital, Oxford University Hospitals National Health Service Foundation Trust, Oxford, United Kingdom.; Moorfields Eye Hospital National Health Service Foundation Trust, London, United Kingdom., Bartz-Schmidt KU; University Eye Hospital, University of Tübingen, Tübingen, Germany., Wilhelm B; STZ eyetrial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Tübingen, Germany.

Publikováno v: JAMA ophthalmology [JAMA Ophthalmol] 2019 Nov 01; Vol. 137 (11), pp. 1247-1254.