Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Rei WATANABE"'
Autor:
Kazumasa Oya, Yoshiyuki Nakamura, Rei Watanabe, Ryota Tanaka, Yuki Ichimura, Noriko Kubota, Yutaka Matsumura, Hideaki Tahara, Naoko Okiyama, Manabu Fujimoto, Toshifumi Nomura, Yasuhiro Fujisawa
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTEribulin mesylate (ERB) is a synthetic analog of halichondrin B, inhibiting tumor cell growth by disrupting microtubule function. Recently, anticancer drugs have been shown to not only act directly on tumor cells but also to exert antitumor e
Externí odkaz:
https://doaj.org/article/e8d35e9ee38e423c8bdae4bb3ecb9b00
Autor:
Yutaka Matsumura, Rei Watanabe, Yasuko Niijima, Haruka Kawakita, Junichi Furuta, Yoshiyuki Nakamura, Yosuke Ishitsuka, Naoko Okiyama, Yasuhiro Fujisawa, Manabu Fujimoto
Publikováno v:
Journal of Cutaneous Immunology and Allergy, Vol 4, Iss 6, Pp 166-169 (2021)
Abstract Although the development of autoimmune disorders is recognized in drug‐induced hypersensitivity syndrome (DIHS), the serial change of B‐cell activity has not been well‐addressed. Herein, the serum levels of IL‐6, IL‐10, B‐cell ac
Externí odkaz:
https://doaj.org/article/a195633fec104f5995783ac11eb0bd5b
Autor:
Takuya Sato, Youichi Ogawa, Kazunori Yokoi, Yuka Nagasaka, Aoha Ishikawa, Ichiro Shiokawa, Manao Kinoshita, Rei Watanabe, Shinji Shimada, Atsushi Tanaka, Akira Momosawa, Tatsuyoshi Kawamura
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Human resident memory regulatory T cells (Tregs) exist in the normal, noninflamed skin. Except one, all previous studies analyzed skin Tregs using full-thickness human skin. Considering that thick dermis contains more Tregs than thin epidermis, the c
Externí odkaz:
https://doaj.org/article/a6c42d4782e64aea90f0bc7f7ad478c6
Autor:
Hanako Koguchi-Yoshioka, Elena Hoffer, Stanley Cheuk, Yutaka Matsumura, Sa Vo, Petra Kjellman, Lucian Grema, Yosuke Ishitsuka, Yoshiyuki Nakamura, Naoko Okiyama, Yasuhiro Fujisawa, Manabu Fujimoto, Liv Eidsmo, Rachael A. Clark, Rei Watanabe
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Koguchi-Yoshioka et al. demonstrate that functional activities and diversity of T cells are highly maintained in the skin of elderly people when compared with those in the blood regardless of the ethnicity of the participants or the experimental proc
Externí odkaz:
https://doaj.org/article/29c808d0282a410097a29f99332c41cb
Autor:
Yosuke Ishitsuka, Tatsuya Ogawa, Yoshiyuki Nakamura, Noriko Kubota, Yasuhiro Fujisawa, Rei Watanabe, Naoko Okiyama, Manabu Fujimoto, Dennis R. Roop, Akemi Ishida-Yamamoto
Publikováno v:
JID Innovations, Vol 2, Iss 1, Pp 100065- (2022)
Cornification involves cytoskeletal cross-linkages in corneocytes (the brick) and the secretion of lipids/adhesion structures to the interstitial space (the mortar). Because the assembly of lipid envelopes precedes corneocyte maturation, loricrin is
Externí odkaz:
https://doaj.org/article/3f586b8bb46046aeb57214cd1957d59e
Autor:
Akimasa Saito, Yoshiyuki Nakamura, Ryota Tanaka, Sae Inoue, Naoko Okiyama, Yosuke Ishitsuka, Hiroshi Maruyama, Rei Watanabe, Kenji Yoshida, Akira Ishiko, Manabu Fujimoto, Satoru Shinkuma, Yasuhiro Fujisawa
Publikováno v:
Acta Dermato-Venereologica, Vol 99, Iss 12, Pp 1166-1169 (2019)
Some bone lesions are reported to mimic bone metastasis on imaging tests. Herein, we report a case of a 55-year-old Japanese man who presented with a skin tumor on the left lower extremity. He also had a history of recurrent generalized cutaneous bli
Externí odkaz:
https://doaj.org/article/389858e1d13e4efcba940ceb8547900d
Autor:
Masamichi Yamaura, Takeshi Yamada, Rei Watanabe, Hitomi Kawai, Suguru Hirose, Hiroki Tajima, Masashi Sato, Yuichi Uchida, Daisuke Suganuma, Yoshiyuki Yamamoto, Toshikazu Moriwaki, Ichinosuke Hyodo
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-6 (2018)
Abstract Background Anal canal cancer occasionally accompanies extramammary Paget disease. Although most of them are squamous cell carcinoma, anal canal adenocarcinoma with neuroendocrine features accompanying secondary extramammary Paget disease has
Externí odkaz:
https://doaj.org/article/fb297464af2e4233b2dc5cdc6e2fcd25
Autor:
Miki Kume, Eiji Kiyohara, Yutaka Matsumura, Hanako Koguchi-Yoshioka, Atsushi Tanemura, Yuma Hanaoka, Mifue Taminato, Hiroki Tashima, Koichi Tomita, Tateki Kubo, Rei Watanabe, Manabu Fujimoto
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In cutaneous T-cell lymphoma (CTCL), which arises from skin-tropic memory T cells, malignant T cells and benign T cells are confined in the same skin lesions. It is thus difficult to evaluate the phenotypic characteristics and functional activities o
Externí odkaz:
https://doaj.org/article/6c52559023404adda83e03f5f6112834
Autor:
Yoshiyuki Nakamura, Zhu Zhenjie, Kazumasa Oya, Ryota Tanaka, Yosuke Ishitsuka, Naoko Okiyama, Rei Watanabe, Yasuhiro Fujisawa
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Recent clinical trials have demonstrated the efficacy of immune checkpoint inhibitors (ICIs) for treating melanoma. However, these previous studies comprised mainly Caucasian populations, in which cutaneous melanoma (CM) is the major clinical type. I
Externí odkaz:
https://doaj.org/article/c25f7041ba9d4db6b21517237e858fc0
Autor:
Ahmed Gehad, Jessica E. Teague, Tiago R. Matos, Victor Huang, Chao Yang, Rei Watanabe, John T. O'Malley, Cornelia L. Trimble, Thomas S. Kupper, Rachael A. Clark
Publikováno v:
Blood Advances, Vol 2, Iss 3, Pp 292-298 (2018)
Abstract: Central memory T cells (TCM) patrol lymph nodes, providing central immunosurveillance against known pathogens, but have not been described as conducting primary tissue immunosurveillance. We analyzed the expression of tissue-homing addressi
Externí odkaz:
https://doaj.org/article/2eb7619042f74b5d877724076f842e8e