Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Rei Otsu"'
Autor:
Jun Muratsu, Masaaki Iwabayashi, Fumihiro Sanada, Yoshiaki Taniyama, Rei Otsu, Hiromi Rakugi, Ryuichi Morishita
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Obesity and its associated chronic inflammation in adipose tissue initiate insulin resistance, which is related to several pathologies including hypertension and atherosclerosis. Previous reports demonstrated that circulating hepatocyte grow
Externí odkaz:
https://doaj.org/article/82442d4d38c943ecb00f89596a73789e
Autor:
Fumihiro Sanada, Yoshiaki Taniyama, Jun Muratsu, Rei Otsu, Hideo Shimizu, Hiromi Rakugi, Ryuichi Morishita
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Aging is a complex process that results from a combination of environmental, genetic, and epigenetic factors. A chronic pro-inflammatory status is a pervasive feature of aging. This chronic low-grade inflammation occurring in the absence of overt inf
Externí odkaz:
https://doaj.org/article/18a83774604b4521b2a36ce8c1d23cf7
Autor:
Fumihiro Sanada, Yoshiaki Taniyama, Jun Muratsu, Rei Otsu, Hideo Shimizu, Hiromi Rakugi, Ryuichi Morishita
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Cellular senescence is the complex process of deterioration that drives the aging of an organism, resulting in the progressive loss of organ function and eventually phenotypic aging. Senescent cells undergo irreversible growth arrest, usually by indu
Externí odkaz:
https://doaj.org/article/18543704a97e46e6b9a5899b8f3c7fce
Autor:
Fumihiro Sanada, Yoshiaki Taniyama, Jun Muratsu, Rei Otsu, Hideo Shimizu, Hiromi Rakugi, Ryuichi Morishita
Publikováno v:
Medicines, Vol 5, Iss 2, p 31 (2018)
The World Health Organization announced that cardiovascular disease is the number one cause of death globally, representing 31% of all global deaths. Coronary artery disease (CAD) affects approximately 5% of the US population aged 40 years and older.
Externí odkaz:
https://doaj.org/article/bb61525c2ec3497980676ea0842d4954
Autor:
Floris van der Flier, Dave Estell, Sina Pricelius, Lydia Dankmeyer, Sander van Stigt Thans, Harm Mulder, Rei Otsuka, Frits Goedegebuur, Laurens Lammerts, Diego Staphorst, Aalt D.J. van Dijk, Dick de Ridder, Henning Redestig
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3489-3497 (2024)
Protein engineering increasingly relies on machine learning models to computationally pre-screen promising novel candidates. Although machine learning approaches have proven effective, their performance on prospective screening data leaves room for i
Externí odkaz:
https://doaj.org/article/88f0342ceb3642ada11fbbe3b130864d
Autor:
Ahmed Makhdoum, Yasuhiro Kotani, Ryuichi Morishita, Rei Otsu, Yoshiaki Taniyama, Amine Mazine, Hon Leong, Subodh Verma, Bobby Yanagawa
Background: A landmark genome-wide association study has linked mutations in the plasma lipoprotein complex lipoprotein(a) [Lp(a)] and aortic stenosis. We attempted to determine whether Lp(a) is a key upstream mediator of aortic stenosis. Methods: Ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43c2d9e9283bc636046e3ebbb985494a
https://doi.org/10.22541/au.164864502.22517521/v1
https://doi.org/10.22541/au.164864502.22517521/v1
Autor:
Yusuke Osawa, Yang An, Yukiko Nishita, Yasumoto Matsui, Marie Takemura, Eleanor M. Simonsick, Hiroshi Shimokata, Rei Otsuka, Hidenori Arai, Luigi Ferrucci
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 746-755 (2024)
Abstract Background Muscle and bone are physiologically interconnected, but joint changes of muscle and bone with aging, and whether the muscle‐bone changes are different by sex and by country has been little studied. We examined longitudinal assoc
Externí odkaz:
https://doaj.org/article/43b860598650489cace4d3c3dfad9119
Autor:
Shu Zhang, Giovanni Sala, Akinori Nakamura, Takashi Kato, Kanae Furuya, Hiroshi Shimokata, Xiang Gao, Yukiko Nishita, Rei Otsuka
Publikováno v:
Nutrition Journal, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background The association of dietary patterns and longitudinal changes in brain volume has rarely been investigated in Japanese individuals. We prospectively investigated this association in middle-aged and older Japanese community-dwelling
Externí odkaz:
https://doaj.org/article/9ebffbfe9ddb4560b0f4f6ba125cfea9
Autor:
Shu Zhang, Li-Ning Peng, Wei-Ju Lee, Yukiko Nishita, Rei Otsuka, Hidenori Arai, Liang-Kung Chen
Publikováno v:
The Journal of Nutrition, Health and Aging, Vol 28, Iss 12, Pp 100403- (2024)
Externí odkaz:
https://doaj.org/article/aa6624cb10fa4bf29b7ea3c28bd5a566
Autor:
Hideo Shimizu, Jun Muratsu, Fumihiro Sanada, Yoshiaki Taniyama, Ryuichi Morishita, Kana Shibata, Rei Otsu, Tatsuya Fujikawa, Kanako May Brule, Hiromi Rakugi
Publikováno v:
Open Medicine Journal. 5:108-118
Introduction: “Aldosterone breakthrough,” which is observed in patients receiving long term treatment with angiotensin blockade, is strongly associated with the increased risk of a declining glomerular filtration rate through the profibrotic acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad8056aef6d2caed7775d0c36c287647
https://doi.org/10.2174/1874220301805010108
https://doi.org/10.2174/1874220301805010108