Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Rei Mimoto"'
Publikováno v:
Cancer Research. 83:3978-3978
Introduction: Tumor progression is the main cause of death in patients with breast cancer. Accumulating evidence suggests that dual-specificity tyrosine-regulated kinase 2 (DYRK2) functions as a tumor suppressor by regulating cell survival, different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2726064b76c22fe04a5637e7bffbe8e2
https://doi.org/10.1158/1538-7445.am2023-3978
https://doi.org/10.1158/1538-7445.am2023-3978
Autor:
Kiyotsugu Yoshida, Hiroshi Takeyama, Toshiaki Morikawa, Yoshimi Imawari, Shinichi Hirooka, Rei Mimoto
Publikováno v:
Cancer Science
Tumor progression is the main cause of death in patients with breast cancer. Accumulating evidence suggests that dual‐specificity tyrosine‐regulated kinase 2 (DYRK2) functions as a tumor suppressor by regulating cell survival, differentiation, pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f21a2c6f67b8508ce458c8737f57cbc
https://doi.org/10.1111/cas.13459
https://doi.org/10.1111/cas.13459
Autor:
Shinichi Hirooka, Ken Eto, Kiyotsugu Yoshida, Daisuke Ito, Rei Mimoto, Katsuhiko Yanaga, Satomi Yogosawa, Takashi Horiuchi
Publikováno v:
Cancer Science
Summary Colorectal cancer is a common cancer and a leading cause of cancer-related death worldwide. The liver is a dominant metastatic site for patients with colorectal cancer. Molecular mechanisms that allow colorectal cancer cells to form liver met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd098949ab5a73a7e1ae8c4f2fb0b07d
http://europepmc.org/articles/PMC5543514
http://europepmc.org/articles/PMC5543514
Autor:
Makiko, Kamio, Ken, Uchida, Rei, Mimoto, Yoshimi, Imawari, Kumiko, Kato, Hiroko, Nogi, Kazumi, Kawase, Yasuo, Toriumi, Yumiko, Onodera, Tsutomu, Kuchiki, Hiroshi, Takeyama
Publikováno v:
Jikeikai medical journal. 63(4):79-85
article
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::9d42e02d0a4df77ffcdc9af4a32d8777
https://ir.jikei.ac.jp/records/4545
https://ir.jikei.ac.jp/records/4545
Autor:
Satomi Yogosawa, Kiyotsugu Yoshida, Rei Mimoto, Atsushi Fushimi, Tadashi Asakura, Hiroko Nogi, Hiroki Saijo, Hiroshi Takeyama
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Various new drugs have been developed for treating recurrent hormone receptor-positive (HR+)/human epidermal receptor 2-negative (HER2−) breast cancer. However, directly identifying effective drugs remains difficult. In this study, we elucidated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec731edb8c50e905dafc8c2b637d3575
https://doi.org/10.1038/s41598-019-49775-w
https://doi.org/10.1038/s41598-019-49775-w
Publikováno v:
Oncogene. 36:1862-1872
Whereas accumulating studies have supported the cancer stem cell theory, a specific therapy targeting a cancer stem cell subpopulation has not been established. Here, we show that dual-specificity tyrosine phosphorylation-kinase 2 (DYRK2) is a novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76079ccb42f2405de91a71c78589284d
https://doi.org/10.1038/onc.2016.349
https://doi.org/10.1038/onc.2016.349
Autor:
Hiroko Nogi, Atsushi Fushimi, Rei Mimoto, Tadashi Asakura, Hiroshi Takeyama, Satomi Yogosawa, Kiyotsugu Yoshida
Publikováno v:
Cancer Research. 80:P6-03
Objectives: Various new drugs have been developed for treating recurrent hormone receptor-positive/human epidermal receptor 2-negative breast cancer. However, directly identifying effective drugs remains difficult. In this study, we elucidated the cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b40998e4e21b7b641a709a7cb04490a
https://doi.org/10.1158/1538-7445.sabcs19-p6-03-14
https://doi.org/10.1158/1538-7445.sabcs19-p6-03-14
Autor:
Kumiko Kato, Yoshimi Imawari, Hiroshi Takeyama, Yasuo Toriumi, Rei Mimoto, Ken Uchida, Hiroko Nogi, Tadashi Kobayashi, Makiko Kamio
Publikováno v:
Cancer Research. 75:P2-06
Background: Metastatic breast cancer is a systemic disease. Our aim was to evaluate the clinical outcomes of pulmonary metastasectomy of recurrent breast tumors and to identify possible prognostic factors. Methods: We reviewed data from a registry of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdfdd09450a8a7d6ef757e7276730faa
https://doi.org/10.1158/1538-7445.sabcs14-p2-06-14
https://doi.org/10.1158/1538-7445.sabcs14-p2-06-14
Autor:
Kiyotsugu Yoshida, Nozomu Yanaihara, Aikou Okamoto, Rei Mimoto, Noriko Yamaguchi, Shinichi Hirooka, Yoshimi Imawari
Publikováno v:
Tumor Biology. 36:5913-5923
Epithelial-mesenchymal-transition (EMT) plays essential roles in ovarian cancer invasion, metastasis, and drug resistance. A hallmark of EMT is the loss of E-cadherin, which is regulated by Snail. Recently, it was shown that dual-specificity tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922fd302016f2e81c342c3d57658f708
https://doi.org/10.1007/s13277-015-3264-y
https://doi.org/10.1007/s13277-015-3264-y
Autor:
Makiko Kamio, Hiroko Nogi, Rei Mimoto, Eijiro Nagasaki, Yasuo Toriumi, Tadashi Kobayashi, Masafumii Suzuki, Ken Uchida, Hiroshi Takeyama, Hisashi Shioya
Publikováno v:
Clinical breast cancer. 17(8)
Sentinel node biopsy (SNB) is used to accurately assess axillary lymph node status in patients with node-negative breast cancer. However, its use after neoadjuvant chemotherapy (NAC) is controversial. We retrospectively assessed the usefulness of SNB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a52c7b634a9af9d0f5b9b69fe188513
https://pubmed.ncbi.nlm.nih.gov/28601382
https://pubmed.ncbi.nlm.nih.gov/28601382