Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Rei Mimoto"'
Publikováno v:
Cancer Research. 83:3978-3978
Introduction: Tumor progression is the main cause of death in patients with breast cancer. Accumulating evidence suggests that dual-specificity tyrosine-regulated kinase 2 (DYRK2) functions as a tumor suppressor by regulating cell survival, different
Autor:
Kiyotsugu Yoshida, Hiroshi Takeyama, Toshiaki Morikawa, Yoshimi Imawari, Shinichi Hirooka, Rei Mimoto
Publikováno v:
Cancer Science
Tumor progression is the main cause of death in patients with breast cancer. Accumulating evidence suggests that dual‐specificity tyrosine‐regulated kinase 2 (DYRK2) functions as a tumor suppressor by regulating cell survival, differentiation, pr
Autor:
Hiroko Nogi, Atsushi Fushimi, Rei Mimoto, Tadashi Asakura, Hiroshi Takeyama, Satomi Yogosawa, Kiyotsugu Yoshida
Publikováno v:
Cancer Research. 80:P6-03
Objectives: Various new drugs have been developed for treating recurrent hormone receptor-positive/human epidermal receptor 2-negative breast cancer. However, directly identifying effective drugs remains difficult. In this study, we elucidated the cl
Autor:
Shinichi Hirooka, Ken Eto, Kiyotsugu Yoshida, Daisuke Ito, Rei Mimoto, Katsuhiko Yanaga, Satomi Yogosawa, Takashi Horiuchi
Publikováno v:
Cancer Science
Summary Colorectal cancer is a common cancer and a leading cause of cancer-related death worldwide. The liver is a dominant metastatic site for patients with colorectal cancer. Molecular mechanisms that allow colorectal cancer cells to form liver met
Autor:
Makiko, Kamio, Ken, Uchida, Rei, Mimoto, Yoshimi, Imawari, Kumiko, Kato, Hiroko, Nogi, Kazumi, Kawase, Yasuo, Toriumi, Yumiko, Onodera, Tsutomu, Kuchiki, Hiroshi, Takeyama
Publikováno v:
Jikeikai medical journal. 63(4):79-85
article
Autor:
Satomi Yogosawa, Kiyotsugu Yoshida, Rei Mimoto, Atsushi Fushimi, Tadashi Asakura, Hiroko Nogi, Hiroki Saijo, Hiroshi Takeyama
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Various new drugs have been developed for treating recurrent hormone receptor-positive (HR+)/human epidermal receptor 2-negative (HER2−) breast cancer. However, directly identifying effective drugs remains difficult. In this study, we elucidated th
Autor:
Kumiko Kato, Yoshimi Imawari, Hiroshi Takeyama, Yasuo Toriumi, Rei Mimoto, Ken Uchida, Hiroko Nogi, Tadashi Kobayashi, Makiko Kamio
Publikováno v:
Cancer Research. 75:P2-06
Background: Metastatic breast cancer is a systemic disease. Our aim was to evaluate the clinical outcomes of pulmonary metastasectomy of recurrent breast tumors and to identify possible prognostic factors. Methods: We reviewed data from a registry of
Publikováno v:
Oncogene. 36:1862-1872
Whereas accumulating studies have supported the cancer stem cell theory, a specific therapy targeting a cancer stem cell subpopulation has not been established. Here, we show that dual-specificity tyrosine phosphorylation-kinase 2 (DYRK2) is a novel
Autor:
Kiyotsugu Yoshida, Nozomu Yanaihara, Aikou Okamoto, Rei Mimoto, Noriko Yamaguchi, Shinichi Hirooka, Yoshimi Imawari
Publikováno v:
Tumor Biology. 36:5913-5923
Epithelial-mesenchymal-transition (EMT) plays essential roles in ovarian cancer invasion, metastasis, and drug resistance. A hallmark of EMT is the loss of E-cadherin, which is regulated by Snail. Recently, it was shown that dual-specificity tyrosine
Autor:
Makiko Kamio, Hiroko Nogi, Rei Mimoto, Eijiro Nagasaki, Yasuo Toriumi, Tadashi Kobayashi, Masafumii Suzuki, Ken Uchida, Hiroshi Takeyama, Hisashi Shioya
Publikováno v:
Clinical breast cancer. 17(8)
Sentinel node biopsy (SNB) is used to accurately assess axillary lymph node status in patients with node-negative breast cancer. However, its use after neoadjuvant chemotherapy (NAC) is controversial. We retrospectively assessed the usefulness of SNB