Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rehwa H. Lee"'
Autor:
Johnathan A. Hopp, Martin S. Obin, A. Bohm, Bruce Y. Lee, Rehwa H. Lee, Allen Taylor, Vadim Y. Arshavsky, Rachelle Gaudet, Barry M. Willardson, Gretchen Meinke
Publikováno v:
Journal of Biological Chemistry. 277:44566-44575
G proteins (Gαβγ) are essential signaling molecules, which dissociate into Gα and Gβγ upon activation by heptahelical membrane receptors. We have identified the βγ subunit complex of the photoreceptor-specific G protein, transducin (T), as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c5a7f7ab6e88990786195391efc0924
https://doi.org/10.1074/jbc.m205308200
https://doi.org/10.1074/jbc.m205308200
Publikováno v:
Genomics. 44:101-109
Phototransduction in the vertebrate rod and cone photoreceptors is regulated by structurally homologous and yet distinct groups of signaling proteins. We have previously identified in bovine retinas a cone-specific G-protein gamma subunit (G gamma c,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d42ebaed6076d2352db577f07ae7eea
https://doi.org/10.1006/geno.1997.4814
https://doi.org/10.1006/geno.1997.4814
Autor:
Fayu Chen, Rehwa H. Lee
Publikováno v:
Biochemical and Biophysical Research Communications. 233:370-374
The interaction between phosducin and betagamma-transducin plays regulatory roles in light adaptation of photoreceptors. Both phosducin and betagamma-transducin undergo post-translational modifications, with phosducin modified by phosphorylation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa0370e2369a43af07a3714c1db76ab
https://doi.org/10.1006/bbrc.1997.6460
https://doi.org/10.1006/bbrc.1997.6460
Autor:
Harvey K. Yamane, Henry K.W. Fong, Rehwa H. Lee, Bernard K.-K. Fung, Dean Bok, Olivia C. Ong, Kim B. Phan
Publikováno v:
Journal of Biological Chemistry. 270:8495-8500
The phototransduction process in cones has been proposed to involve a G protein that couples the signal from light-activated visual pigment to the effector cyclic GMP phosphodiesterase. Previously, we have identified and purified a G beta gamma compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77aa014d281272c62b604e87f46142cc
https://doi.org/10.1074/jbc.270.15.8495
https://doi.org/10.1074/jbc.270.15.8495
Autor:
Ning Qin, Wolfgang Baehr, Rehwa H. Lee, Vien Holcombe, Richard L. Hurwitz, Steven J. Pittler, Cheryl M. Craft, Gail C. Wright, Richard N. Lolley, Michael L. Suber
Publikováno v:
Proceedings of the National Academy of Sciences. 90:3968-3972
Irish setter dogs affected with a rod/cone dysplasia (locus designation, rcd1) display markedly elevated levels of retinal cGMP during postnatal development. The photoreceptor degeneration commences approximately 25 days after birth and culminates at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213a05edfebde5d49ffbcb070023e4d3
https://doi.org/10.1073/pnas.90.9.3968
https://doi.org/10.1073/pnas.90.9.3968
Publikováno v:
Journal of Biological Chemistry. 267:24776-24781
Vertebrate retinal cones play a major role in both photopic vision and color perception. Although the molecular mechanism of visual excitation in the cone is not as well understood as in the rod, it is generally thought to involve a cone-specific G p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57798bd95951c68f07f72c8feb0b12e4
https://doi.org/10.1016/s0021-9258(18)35831-9
https://doi.org/10.1016/s0021-9258(18)35831-9
Publikováno v:
Genomics. 10:400-409
The pineal gland contains a soluble phosphoprotein, phosducin, which is homologous to that of retinal photoreceptors. Phosducin has been shown to bind the beta, gamma subunits of the retinal G-protein transducin. Retinal phosducin has been cloned and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a614654bf340e1163e70195584f6c0a
https://doi.org/10.1016/0888-7543(91)90325-9
https://doi.org/10.1016/0888-7543(91)90325-9
Autor:
Fatima Ali, Li Li, Nikita Pozdeyev, Stanislav Rozov, P. Michael Iuvone, Gianluca Tosini, Rehwa H. Lee
Many aspects of photoreceptor metabolism are regulated as diurnal or circadian rhythms. The nature of the signals that drive rhythms in mouse photoreceptors is unknown. Dopamine amacrine cells in mouse retina express core circadian clock genes, leadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49302d0587cd458192453da313f7b7b5
https://europepmc.org/articles/PMC2440701/
https://europepmc.org/articles/PMC2440701/
Autor:
Martin, Obin, Bruce Y, Lee, Gretchen, Meinke, Andrew, Bohm, Rehwa H, Lee, Rachelle, Gaudet, Johnathan A, Hopp, Vadim Y, Arshavsky, Barry M, Willardson, Allen, Taylor
Publikováno v:
The Journal of biological chemistry. 277(46)
G proteins (Galphabetagamma) are essential signaling molecules, which dissociate into Galpha and Gbetagamma upon activation by heptahelical membrane receptors. We have identified the betagamma subunit complex of the photoreceptor-specific G protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::86db5914bc1cfe967346b2a4d82940c6
https://pubmed.ncbi.nlm.nih.gov/12215439
https://pubmed.ncbi.nlm.nih.gov/12215439
Autor:
Richard N. Lolley, Rehwa H. Lee
Publisher Summary Phosducin is a 33-kDa phosphoprotein that is found in photoreceptors of the vertebrate retina and in pinealocytes of the pineal gland. In its native conformation, phosducin exists as a 77-kDa heterotrimeric complex with the βγ sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::996ea1140f8118bc633f8608fdb7ee76
https://doi.org/10.1016/b978-0-12-185279-5.50018-2
https://doi.org/10.1016/b978-0-12-185279-5.50018-2