Comprehensive analysis and outcomes of hybridization of physiologically active heterocycles targeting epidermal growth factor receptor (EGFR).

Autor: Kaur M; Synthetic and Medicinal Chemistry Laboratory, Department of Chemistry, Punjabi University, Patiala, 147002, India., Rehman HM; School of Biochemistry and Biotechnology, University of the Punjab, Lahore, Punjab, Pakistan., Wu Y; Department of Chemistry, The Hong Kong University of Science and Technology, China., Kaur G; Synthetic and Medicinal Chemistry Laboratory, Department of Chemistry, Punjabi University, Patiala, 147002, India., Hammad HM; School of Biochemistry and Biotechnology, University of the Punjab, Lahore, Punjab, Pakistan., Usmani YS; Department of Industrial Engineering, College of Engineering, King Saud University, Riyadh, 11421, Saudi Arabia., Kaur A; Synthetic and Medicinal Chemistry Laboratory, Department of Chemistry, Punjabi University, Patiala, 147002, India., Bansal M; Synthetic and Medicinal Chemistry Laboratory, Department of Chemistry, Punjabi University, Patiala, 147002, India. Electronic address: jindal_manisha@yahoo.co.in.

Publikováno v: Computers in biology and medicine [Comput Biol Med] 2024 Nov 11; Vol. 184, pp. 109347. Date of Electronic Publication: 2024 Nov 11.

An in silico approach uncovering the competency of oncolytic human adenovirus 52 for targeted breast cancer virotherapy.

Autor: Naveed M; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, 54590, Pakistan. naveed.quaidian@gmail.com., Batool Z; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, 54590, Pakistan., Aziz T; Laboratory of Animal Health Food Hygiene and Quality, University of Ioannina, Arta, Greece., Javed K; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, 54590, Pakistan., Ali N; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, 54590, Pakistan., Rehman HM; School of Biochemistry and Biotechnology, University of the Punjab, Lahore, Pakistan., Alharbi M; Department of Pharmacology and Toxicology College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Alasmari AF; Department of Pharmacology and Toxicology College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Alshammari A; Department of Pharmacology and Toxicology College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. iwockd@gmail.com.

Publikováno v: Scientific reports [Sci Rep] 2024 Nov 02; Vol. 14 (1), pp. 26405. Date of Electronic Publication: 2024 Nov 02.

Design and computational analysis of a novel Leptulipin-p28 fusion protein as a multitarget anticancer therapy in breast cancer.

Autor: Khalid S; Centre for Applied Molecular Biology (CAMB), 87-West canal, Bank Road, University of the Punjab, Lahore 53700, Pakistan., Rehman HM; Centre for Applied Molecular Biology (CAMB), 87-West canal, Bank Road, University of the Punjab, Lahore 53700, Pakistan.; University Institute of Medical Lab Technology, Faculty of Allied Health Sciences, The University of Lahore, 54590 Pakistan., Al-Qassab Y; Clinical Communicable Diseases Research Unit/College of Medicine/University of Baghdad, Baghdad, Iraq., Ahmad I; Department of Clinical Laboratory Sciences, College of Applied Medical Science, King Khalid University, Abha, Saudi Arabia., Fatima T; Centre for Applied Molecular Biology (CAMB), 87-West canal, Bank Road, University of the Punjab, Lahore 53700, Pakistan., Mubasher MM; Department of Information Technology, University of the Punjab, Lahore, Pakistan., Kalsoom M; Centre for Applied Molecular Biology (CAMB), 87-West canal, Bank Road, University of the Punjab, Lahore 53700, Pakistan., Nadeem T; Center of Excellence in Molecular Biology (CEMB), University of The Punjab, Lahore53700, Pakistan., Bashir H; Centre for Applied Molecular Biology (CAMB), 87-West canal, Bank Road, University of the Punjab, Lahore 53700, Pakistan.

Publikováno v: Toxicology research [Toxicol Res (Camb)] 2024 Oct 13; Vol. 13 (5), pp. tfae174. Date of Electronic Publication: 2024 Oct 13 (Print Publication: 2024).

Investigation of therapeutic potential of the Il24-p20 fusion protein against breast cancer: an in-silico approach.

Autor: Qureshi S; Centre for Applied Molecular Biology, University of the Punjab, 87-West canal, Bank Road, Lahore, 53700 Pakistan., Ahmed N; Centre of Excellence in Molecular Biology (CEMB), University of the Punjab, 87-West canal, Bank Road, Lahore, 53700 Pakistan., Rehman HM; Centre for Applied Molecular Biology, University of the Punjab, 87-West canal, Bank Road, Lahore, 53700 Pakistan.; University Institute of Medical Laboratory Technology, Faculty of Allied Health Science, University of Lahore, Lahore, 54590 Pakistan., Amirzada MI; Department of Pharmacy, COMSATS University, Islamabad Abbottabad, Pakistan., Saleem F; Centre for Applied Molecular Biology, University of the Punjab, 87-West canal, Bank Road, Lahore, 53700 Pakistan.; University Institute of Medical Laboratory Technology, Faculty of Allied Health Science, University of Lahore, Lahore, 54590 Pakistan., Waheed K; Centre for Applied Molecular Biology, University of the Punjab, 87-West canal, Bank Road, Lahore, 53700 Pakistan.; University Institute of Medical Laboratory Technology, Faculty of Allied Health Science, University of Lahore, Lahore, 54590 Pakistan., Chaudhry A; Department of Biology, Lahore Garrison University, Avenue 4, sector phase 6 DHA, Lahore, Pakistan., Kafait I; Institute of Molecular Biotechnology, Graz University of Technology, Graz, Austria., Akram M; Centre for Applied Molecular Biology, University of the Punjab, 87-West canal, Bank Road, Lahore, 53700 Pakistan., Bashir H; Centre for Applied Molecular Biology, University of the Punjab, 87-West canal, Bank Road, Lahore, 53700 Pakistan.

Publikováno v: In silico pharmacology [In Silico Pharmacol] 2024 Sep 18; Vol. 12 (2), pp. 84. Date of Electronic Publication: 2024 Sep 18 (Print Publication: 2024).

Rational computational design and development of an immunogenic multiepitope vaccine incorporating transmembrane proteins of Staphylococcus lugdunensis.

Autor: Naveed M; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan. Electronic address: naveed.quaidian@gmail.com., Fatima F; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan., Aziz T; Laboratory of Animal Health Food Hygiene and Quality University of Ioannina Arta Greece, Greece; Institute of Molecular Biology and Biotechnology, The University of Lahore, Punjab, Pakistan. Electronic address: iwockd@gmail.com., Iftikhar MA; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan., Javed T; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan., Majeed MN; Department of Biotechnology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan., Rehman HM; Institute of Biochemistry and Biotechnology, University of the Punjab, Lahore 54590, Punjab, Pakistan., Khan A; Department of Biotechnology, Faculty of Sciences, International Islamic University, Islamabad, Pakistan., Alhomrani M; Department of Clinical Laboratory Sciences, The Faculty of Applied Medical Sciences, Taif University, Taif, Saudi Arabia., Alsanie WF; Department of Clinical Laboratory Sciences, The Faculty of Applied Medical Sciences, Taif University, Taif, Saudi Arabia., Alamri AS; Department of Clinical Laboratory Sciences, The Faculty of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.

Publikováno v: International immunopharmacology [Int Immunopharmacol] 2024 Dec 25; Vol. 143 (Pt 1), pp. 113345. Date of Electronic Publication: 2024 Oct 12.