Výsledky vyhledávání - "Reham Waheed Hammad"

Akademický článek

New intranasal cross-linked mosapride xyloglucan pluronics micelles (MOS-XPMs) for reflux esophagitis disease: In-vitro optimization and improved therapeutic efficacy

Autor: Reham Waheed Hammad, Rania Abdel-Basset Sanad, Nevine Shawky Abdelmalak, Faisal A. Torad, Randa Latif

Publikováno v: Journal of Advanced Research, Vol 23, Iss , Pp 83-94 (2020)

Mosapride belongs to class IV in Biopharmaceutics Classification System and is used in the treatment of reflux esophagitis. It exhibits poor bioavailability due to limited permeability, solubility and extensive first-pass metabolism. In this study, i

Externí odkaz: https://doaj.org/article/6bd3ac777a73414b8f85752ecf06931a

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Architecting novel multilayer nanosponges for co-administration of two drugs managing high-risk type II diabetes mellitus patients suffering from cardiovascular diseases

Autor: Reham Waheed Hammad, Rania Abdel-Basset Sanad, Nevine Shawky Abdelmalak, Randa Latif

Publikováno v: International journal of biological macromolecules. 220

Nanosponges are porous solid nanoparticles composed of hyper-cross-linked polymers that serve as specific micro-domains designed for the co-encapsulation of two drugs with different chemical structures. Our goal was to engineer a novel assembly of mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cd8d20f38c0b458c38dc8e7eeaad9c
https://pubmed.ncbi.nlm.nih.gov/36115452

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New intranasal cross-linked mosapride xyloglucan pluronics micelles (MOS-XPMs) for reflux esophagitis disease

Autor: Rania Abdel-Basset Sanad, Faisal A. Torad, Nevine Shawky Abdelmalak, Randa Latif, Reham Waheed Hammad

Publikováno v: Journal of Advanced Research, Vol 23, Iss, Pp 83-94 (2020)
Journal of Advanced Research

Graphical abstract
Highlight • Mosapride was loaded inside crosslinked Xyloglucan Pluronic micelle (MOS-XPMs). • (MOS-XPMs) showed improved stability and mucoadhesiveness. • MOS-XPMs systems showed a rapid release of drug located in the sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c076eee7ea04a47a76a7596c5d16095
https://pubmed.ncbi.nlm.nih.gov/32089877

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Intranasal Surface-Modified Mosapride Citrate-Loaded Nanostructured Lipid Carriers (MOS-SMNLCs) for Treatment of Reflux Diseases: In vitro Optimization, Pharmacodynamics, and Pharmacokinetic Studies

Autor: Faisal A. Torad, Nevine Shawky Abdelmalk, Randa latif Aziz, Reham Waheed Hammad, Rania Abdel Baset Sanad

Publikováno v: AAPS PharmSciTech. 19(8)

Gastroesophageal reflux disease (GERD) is an esophageal injury occurred when the stomach contents reflux abnormally into the esophagus. GERD complications include esophageal adenocarcinoma. Mosapride (MOS) is a safe prokinetic agent potentially used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5225b54a58d339a94ff8bee42d3d3e40
https://pubmed.ncbi.nlm.nih.gov/30280358

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