Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Reham K. Abuhijjleh"'
Autor:
Reham K. Abuhijjleh, Samiullah Shabbir, Ahmed M. Al-Abd, Nada H. Jiaan, Shahad Alshamil, Eman M. El-labbad, Sherief I. Khalifa
Publikováno v:
PeerJ, Vol 9, p e11778 (2021)
Marine life has provided mankind with unique and extraordinary chemical structures and scaffolds with potent biological activities. Many organisms and secondary metabolites derived from fungi and symbionts are found to be more environmentally friendl
Externí odkaz:
https://doaj.org/article/9d19687decc4449ca11dcf17184c45e5
Abstract 1049: Modulating the polymorphic UGT1A1 gene to enhance camptothecin anti-colorectal effect
Publikováno v:
Cancer Research. 82:1049-1049
Several semisynthetic analogs of camptothecin (CPT) are used clinically for the treatment of various types of cancers, including colorectal (CRC) cancer, despite their severe, potentially life-threatening toxicities. Studies defined key mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13dc0ca1cdc286b65ab5b33895b9e596
https://doi.org/10.1158/1538-7445.am2022-1049
https://doi.org/10.1158/1538-7445.am2022-1049