Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Reha Yildiriman"'
Autor:
Moritz Schütte, Thomas Risch, Nilofar Abdavi-Azar, Karsten Boehnke, Dirk Schumacher, Marlen Keil, Reha Yildiriman, Christine Jandrasits, Tatiana Borodina, Vyacheslav Amstislavskiy, Catherine L. Worth, Caroline Schweiger, Sandra Liebs, Martin Lange, Hans- Jörg Warnatz, Lee M. Butcher, James E. Barrett, Marc Sultan, Christoph Wierling, Nicole Golob-Schwarzl, Sigurd Lax, Stefan Uranitsch, Michael Becker, Yvonne Welte, Joseph Lewis Regan, Maxine Silvestrov, Inge Kehler, Alberto Fusi, Thomas Kessler, Ralf Herwig, Ulf Landegren, Dirk Wienke, Mats Nilsson, Juan A. Velasco, Pilar Garin-Chesa, Christoph Reinhard, Stephan Beck, Reinhold Schäfer, Christian R. A. Regenbrecht, David Henderson, Bodo Lange, Johannes Haybaeck, Ulrich Keilholz, Jens Hoffmann, Hans Lehrach, Marie-Laure Yaspo
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
The heterogeneity of colorectal cancer has important clinical and therapeutic implications. Here the authors analysed the responses of a large biobank of organoids and xenografts derived from colorectal patients to a panel of clinically relevant ther
Externí odkaz:
https://doaj.org/article/00f477ba693042c6918f1164e120c8e4
Autor:
Catherine L. Worth, Vyacheslav Amstislavskiy, Yvonne Welte, Lee M. Butcher, Tatiana Borodina, Jens Hoffmann, Christoph Wierling, Christian R. A. Regenbrecht, Sandra Liebs, Caroline Schweiger, Moritz Schütte, Juan A. Velasco, Martin Lange, David Henderson, Marc Sultan, Johannes Haybaeck, Michael Becker, Maxine Silvestrov, Christoph Reinhard, Christine Jandrasits, Karsten Boehnke, Nicole Golob-Schwarzl, Sigurd Lax, Mats Nilsson, Marie-Laure Yaspo, Thomas Kessler, Reha Yildiriman, Ulrich Keilholz, Hans-Jörg Warnatz, Pilar Garin-Chesa, Stefan Uranitsch, Bodo Lange, Dirk Wienke, Nilofar Abdavi-Azar, Dirk Schumacher, Ralf Herwig, James E. Barrett, Stephan Beck, Inge Kehler, Thomas Risch, Alberto Fusi, Hans Lehrach, Ulf Landegren, Marlen Keil, Reinhold Schäfer, Joseph L. Regan
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
Nature Communications
Schutte, M, Risch, T, Abdavi-Azar, N, Boehnke, K, Schumacher, D, Keil, M, Yildiriman, R, Jandrasits, C, Borodina, T, Amstislavskiy, V, Worth, C L, Schweiger, C, Liebs, S, Lange, M, Warnatz, H J, Butcher, L M, Barrett, J E, Sultan, M, Wierling, C, Golob-Schwarzl, N, Lax, S, Uranitsch, S, Becker, M, Welte, Y, Regan, J L, Silvestrov, M, Kehler, I, Fusi, A, Kessler, T, Herwig, R, Landegren, U, Wienke, D, Nilsson, M, Velasco, J A, Garin-Chesa, P, Reinhard, C, Beck, S, Schäfer, R, Regenbrecht, C R A, Henderson, D, Lange, B, Haybaeck, J, Keilholz, U, Hoffmann, J, Lehrach, H & Yaspo, M-L 2017, ' Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors ', Nature Communications, vol. 8, 14262, pp. 1-19 . https://doi.org/10.1038/ncomms14262
Nature Communications
Schutte, M, Risch, T, Abdavi-Azar, N, Boehnke, K, Schumacher, D, Keil, M, Yildiriman, R, Jandrasits, C, Borodina, T, Amstislavskiy, V, Worth, C L, Schweiger, C, Liebs, S, Lange, M, Warnatz, H J, Butcher, L M, Barrett, J E, Sultan, M, Wierling, C, Golob-Schwarzl, N, Lax, S, Uranitsch, S, Becker, M, Welte, Y, Regan, J L, Silvestrov, M, Kehler, I, Fusi, A, Kessler, T, Herwig, R, Landegren, U, Wienke, D, Nilsson, M, Velasco, J A, Garin-Chesa, P, Reinhard, C, Beck, S, Schäfer, R, Regenbrecht, C R A, Henderson, D, Lange, B, Haybaeck, J, Keilholz, U, Hoffmann, J, Lehrach, H & Yaspo, M-L 2017, ' Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors ', Nature Communications, vol. 8, 14262, pp. 1-19 . https://doi.org/10.1038/ncomms14262
Colorectal carcinoma represents a heterogeneous entity, with only a fraction of the tumours responding to available therapies, requiring a better molecular understanding of the disease in precision oncology. To address this challenge, the OncoTrack c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d73ec2fac88333758e141522ab23ec
https://doi.org/10.17169/refubium-24207
https://doi.org/10.17169/refubium-24207
Autor:
Alexander Kuehn, Svetlana Peycheva, Bodo Lange, Christoph Wierling, Verena Lehmann, Thomas Kessler, Felix Dreher, Hans Lehrach, Reha Yildiriman
Publikováno v:
Cancer Research. 74:350-350
Traditionally, tumors have been classified based on their tissue of origin and their histopathological characteristics and consequently patients are divided into groups where they are treated identically despite substantial differences in genetic pro