Zobrazeno 1 - 10
of 15 125
pro vyhledávání: '"Regulatory T-cell"'
Autor:
Won-Dong Kim, Don D. Sin
Publikováno v:
COPD, Vol 21, Iss 1, Pp 1-11 (2024)
AbstractChronic obstructive pulmonary disease (COPD) is caused by smoking, but only a small proportion of smokers have disease severe enough to develop COPD. COPD is not always progressive. The question then arises as to what explains the different t
Externí odkaz:
https://doaj.org/article/a73fc2ca4d1947a69109af353104d22a
Autor:
Hao Wang, Lin Yao, Jinming Chen, Yanyan Li, Zuopeng Su, Yongsheng Liu, Wen Li, Yun Xiong, Heyang Gao, Xiao Zhang, Youxin Zhou
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background Glioblastoma (GBM) is an immunosuppressive, universally lethal cancer driven by glioblastoma stem cells (GSCs). The interplay between GSCs and immunosuppressive microglia plays crucial roles in promoting the malignant growth of GB
Externí odkaz:
https://doaj.org/article/e6f60311a081441cbda1e20c8b300e8f
Autor:
Tomonori Oka, Tatsuya Hasegawa, Truelian Lee, Valeria S. Oliver-Garcia, Mahsa Mortaja, Marjan Azin, Satoshi Horiba, Sabrina S. Smith, Sara Khattab, Kathryn E. Trerice, Steven T. Chen, Yevgeniy R. Semenov, Shadmehr Demehri
Publikováno v:
JID Innovations, Vol 5, Iss 1, Pp 100324- (2025)
Adult human skin contains nearly twice as many T cells as the peripheral blood, which include tissue-resident memory T cells. However, the precise mechanisms maintaining tissue-resident memory T cells in the healthy skin remain unclear. Using normal
Externí odkaz:
https://doaj.org/article/c8c93490ea764a77b1fdd0f1902d549c
Autor:
Ruichen Huang, Qiao Zhou, Jiajun Liu, Yang Xia, Yang Jiao, Bi Zhao, Tangtao Feng, Haosu Zhou, Xiuyan Song, Hao Qin, Jun Wang, Lan Cheng, Yunye Ning, Qinying Sun, Yanfang Liu, Xiaoping Su, Yuchao Dong, Wei Zhang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 59, Iss , Pp 101088- (2025)
Background: The neoantigen vaccine has remarkable potential in treating advanced cancer due to its tumor specificity and ability to bypass central tolerance mechanisms. However, numerous neoantigens show poor immunogenicity, and the immune inhibitory
Externí odkaz:
https://doaj.org/article/8d8f5220b7ee47d9bbd4ce58613665ec
Publikováno v:
Frontiers in Ophthalmology, Vol 4 (2024)
PurposeThyroid eye disease (TED) primarily occurs in hyperthyroid patients, sometimes resulting in poor visual prognosis. Although other autoimmune diseases have been reported to be associated with serum programmed cell death 1 (PD-1), the relationsh
Externí odkaz:
https://doaj.org/article/07c3210f10bc45e9a5fb17c8ce3be98e
Autor:
Rui Wang, Qing Liang, Qian Zhang, Shuchao Zhao, Yuxiang Lin, Bing Liu, Yinjiang Ma, Xiaoya Mai, Quanze Fu, Xiaorui Bao, Nan Wang, Binglin Chen, Peng Yan, Yongsheng Zhu, Kejia Wang
Publikováno v:
Advanced Science, Vol 11, Iss 45, Pp n/a-n/a (2024)
Abstract Inflammation is highlighted as an initial factor that helps orchestrate liver reconstitution. However, the precise mechanisms controlling inflammation during liver reconstitution have not been fully elucidated. In this study, a clear immune
Externí odkaz:
https://doaj.org/article/2529ac129615427a95274deeb8e29def
Autor:
Russell W. Cochrane, Rob A. Robino, Bryan Granger, Eva Allen, Silvia Vaena, Martin J. Romeo, Aguirre A. de Cubas, Stefano Berto, Leonardo M.R. Ferreira
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 4, Pp 101385- (2024)
Regulatory T cells (Tregs) are promising cellular therapies to induce immune tolerance in organ transplantation and autoimmune disease. The success of chimeric antigen receptor (CAR) T cell therapy for cancer has sparked interest in using CARs to gen
Externí odkaz:
https://doaj.org/article/e83f1c9eae254dd28e271f8109a4c246
Autor:
Mareike Mannewitz, Thomas Kolben, Carolin Perleberg, Sarah Meister, Laura Hahn, Sophie Mitter, Elisa Schmoeckel, Sven Mahner, Stefanie Corradini, Fabian Trillsch, Mirjana Kessler, Udo Jeschke, Susanne Beyer
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102116- (2024)
Objectives: The chemokine CCL22 is recognized for recruiting immunosuppressive regulatory T-cells (Treg) that contribute to disease progression in various tumor entities helping them to evade the host immune response. Our study aims to identify the e
Externí odkaz:
https://doaj.org/article/a1d7f82746124e98acf4d69eadacae70