Zobrazeno 1 - 10
of 802
pro vyhledávání: '"Regulatory T cells (Tregs)"'
Autor:
Joanna Chmiel, Mariusz Stasiak, Maria Skrzypkowska, Lucjan Samson, Piotr Łuczkiewicz, Piotr Trzonkowski
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36512- (2024)
Cellular therapies utilizing regulatory T cells (Tregs) have flourished in the autoimmunity space as a new pillar of medicine. These cells have shown a great promise in the treatment of such devastating conditions as type 1 diabetes mellitus (T1DM),
Externí odkaz:
https://doaj.org/article/719b97bd43d54ce881f54fde55f1c5b9
Autor:
Alexis Yero, Tao Shi, Julien A. Clain, Ouafa Zghidi-Abouzid, Gina Racine, Cecilia T. Costiniuk, Jean-Pierre Routy, Jérôme Estaquier, Mohammad-Ali Jenabian
Publikováno v:
Viruses, Vol 16, Iss 10, p 1609 (2024)
HIV infection significantly affects the frequencies and functions of immunoregulatory CD3+CD4−CD8− double-negative (DN) T-cells, while the effect of early antiretroviral therapy (ART) initiation on these cells remains understudied. DN T-cell subs
Externí odkaz:
https://doaj.org/article/ae57dd0368cc415c972bb1891580decd
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSystemic lupus erythematosus (SLE) as an autoimmune disease can relate to an imbalance between regulatory T cells (Tregs) and Th17 cells. Previous reports have shown that Myc-induced nuclear antigen (Mina) 53 protein is involved in the de
Externí odkaz:
https://doaj.org/article/56db31a0d69b46d785d8d2277e8a5152
Autor:
Lifen Huang, Junbin Huang, Nannan Tang, Hongman Xue, Shaofen Lin, Su Liu, Qihui Chen, Yinsi Lu, Qian Liang, Yun Wang, Qingqing Zhu, Guoxing Zheng, Yun Chen, Chengming Zhu, Chun Chen
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26731- (2024)
Deficiency in regulatory T cells (Tregs) is an important mechanism underlying the pathogenesis of pediatric aplastic anemia, but its specific mechanism is unclear. In our study, we aimed to investigate whether IL-2/STAT5 can regulate the proliferatio
Externí odkaz:
https://doaj.org/article/4f49d5c8a36d4eba88f14444af46ca0e
Autor:
Samuel Knoedler, Leonard Knoedler, Martin Kauke-Navarro, Yuval Rinkevich, Gabriel Hundeshagen, Leila Harhaus, Ulrich Kneser, Bohdan Pomahac, Dennis P. Orgill, Adriana C. Panayi
Publikováno v:
Military Medical Research, Vol 10, Iss 1, Pp 1-23 (2023)
Abstract As the body’s integumentary system, the skin is vulnerable to injuries. The subsequent wound healing processes aim to restore dermal and epidermal integrity and functionality. To this end, multiple tissue-resident cells and recruited immun
Externí odkaz:
https://doaj.org/article/7987edf3c4cb4c90866e3d85b136703a
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7346 (2024)
Regulatory T cells (Tregs) possess unique immunosuppressive activity among CD4-positive T cells. Tregs are ubiquitously present in mammals and function to calm excessive immune responses, thereby suppressing allergies or autoimmune diseases. On the o
Externí odkaz:
https://doaj.org/article/84803c5cc2ed48289334b9fd3c8a3eda
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Radiation-induced lung injury is a common complication associated with radiotherapy. It is characterized by early-stage radiation pneumonia and subsequent radiation pulmonary fibrosis. However, there is currently a lack of effective therapeutic strat
Externí odkaz:
https://doaj.org/article/c4d375a6a61b414081055191a4d3d75d
Autor:
Fengxia Bai, Longchao Han, Jifeng Yang, Yuxiu Liu, Xiangmeng Li, Yaqin Wang, Ruijian Jiang, Zhaomu Zeng, Yan Gao, Haisong Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
PurposeThe pathogenesis of renal fibrosis (RF) involves intricate interactions between profibrotic processes and immune responses. This study aimed to explore the potential involvement of the pyroptosis signaling pathway in immune microenvironment re
Externí odkaz:
https://doaj.org/article/73e2f2a6ad5346bc968829e83348f550
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Regulatory T cells (Tregs) are a very specialized subset of T lymphocytes: their main function is controlling immune responses during inflammation. T-regs involvement in autoimmune and immune-mediated rheumatic diseases is well-described. Here, we cr
Externí odkaz:
https://doaj.org/article/9d0517104af24293a42c2a038a4264bc
Autor:
Hania Arain, Tina Patel, Nicoleta Mureanu, Athina Efthymiou, Giovanna Lombardi, Timothy Tree, Kypros H. Nicolaides, Panicos Shangaris
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundGestational diabetes (GDM) affects approximately 14% of pregnancies globally and is associated with short- and long-term complications for both the mother and child. In addition, GDM has been linked to chronic low-grade inflammation with re
Externí odkaz:
https://doaj.org/article/00e712c4a7c14e88b6b349ac611117aa