Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Regis Bobe"'
Autor:
Luigi Maione, Frederique Albarel, Philippe Bouchard, Megan Gallant, Colleen A Flanagan, Regis Bobe, Joelle Cohen-Tannoudji, Rosario Pivonello, Annamaria Colao, Thierry Brue, Robert P Millar, Marc Lombes, Jacques Young, Anne Guiochon-Mantel, Jerome Bouligand
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69616 (2013)
Normosmic congenital hypogonadotropic hypogonadism (nCHH) is a rare reproductive disease leading to lack of puberty and infertility. Loss-of-function mutations of GNRH1 gene are a very rare cause of autosomal recessive nCHH. R31C GNRH1 is the only mi
Externí odkaz:
https://doaj.org/article/a9255ab17ae24c32ade14102c14476b2
Autor:
Luigi Maione, Frederique Albarel, Philippe Bouchard, Megan Gallant, Colleen A. Flanagan, Regis Bobe, Joelle Cohen-Tannoudji, Rosario Pivonello, Annamaria Colao, Thierry Brue, Robert P. Millar, Marc Lombes, Jacques Young, Anne Guiochon-Mantel, Jerome Bouligand
Publikováno v:
PLoS ONE, Vol 8, Iss 8 (2013)
Externí odkaz:
https://doaj.org/article/82a2395d5f8d4a8fbb72e52719c7436b
Autor:
Elisa, Rossi, Alexandre, Kauskot, François, Saller, Elisa, Frezza, Sonia, Poirault-Chassac, Anna, Lokajczyk, Pierre, Bourdoncle, Bruno, Saubaméa, Pascale, Gaussem, Miguel, Pericacho, Regis, Bobe, Christilla, Bachelot-Loza, Samuela, Pasquali, Carmelo, Bernabeu, David M, Smadja
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, MDPI, 2021, 22 (16), pp.8837. ⟨10.3390/ijms22168837⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences, Vol 22, Iss 8837, p 8837 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, MDPI, 2021, 22 (16), pp.8837. ⟨10.3390/ijms22168837⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences, Vol 22, Iss 8837, p 8837 (2021)
Endoglin (Eng) is an endothelial cell (EC) transmembrane glycoprotein involved in adhesion and angiogenesis. Eng mutations result in vessel abnormalities as observed in hereditary hemorrhagic telangiectasia of type 1. The role of Eng was investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dbdafb46601ce437e9240692ab499c5d
http://hdl.handle.net/10261/260324
http://hdl.handle.net/10261/260324
Autor:
Alain Stepanian, Simon Msika, Aurélie Kondratieff, Cécile V. Denis, Dominique de Prost, Muriel Coupaye, Yann Becker, Laurence Salomon, Kevin Zuber, Regis Bobe, Jean-Philippe Rosa, Jose J. Lopez, Christelle Repérant, Marion Pépin, Ziane Elaib
Publikováno v:
Thrombosis and Haemostasis. 119:384-396
In obesity, platelets are described as hyperactive, mainly based on increased platelet size and presence of pro-thrombotic plasmatic molecules. We explored platelet functions, including calcium signalling in obesity, and the effect of weight loss. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e85044347a912f87a4ec73e82539467
https://doi.org/10.1055/s-0038-1677033
https://doi.org/10.1055/s-0038-1677033
Autor:
Cécile V. Denis, Frédéric Adam, Delphine Borgel, Regis Bobe, Jean-Philippe Rosa, Ziane Elaib, Miao Feng, Marijke Bryckaert
Publikováno v:
Circulation Research
Circulation Research, American Heart Association, 2020, 127 (7), pp.e166-e183. ⟨10.1161/CIRCRESAHA.119.316090⟩
Circulation Research, American Heart Association, 2020, 127 (7), pp.e166-e183. ⟨10.1161/CIRCRESAHA.119.316090⟩
Rationale: Ca 2+ signaling is a key and ubiquitous actor of cell organization and its modulation controls many cellular responses. SERCAs (sarco-endoplasmic reticulum Ca 2+ -ATPases) pump Ca 2+ into internal stores that play a major role in the cytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54e26d94be7dc042d9ca3cb699d0d2c
https://doi.org/10.1161/circresaha.119.316090
https://doi.org/10.1161/circresaha.119.316090
Autor:
Florent Raffin, Regis Bobe, François Saller, François-Xavier Boittin, Kathia Beddek, Diane Riccobono, Delphine Borgel
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
The Transient Receptor Potential Vanilloid 4 (TRPV4) of endothelial cells contributes to many important functions including the regulation of Ca2+ homeostasis, cell volume, endothelial barrier permeability, and smooth muscle tone. However, its role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8705ad90d55e15bf03ab6555e7071893
https://pubmed.ncbi.nlm.nih.gov/33512067
https://pubmed.ncbi.nlm.nih.gov/33512067
Autor:
Jose Sanchez-Collado, Regis Bobe, Jose J. Lopez, Juan A. Rosado, Isaac Jardín, Letizia Albarran, Tarik Smani, Nuria Bermejo, Pedro C. Redondo
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:386-397
Objective— Here, we provide evidence for the role of FLNA (filamin A) in the modulation of store-operated calcium entry (SOCE). Approach and Results— SOCE is a major mechanism for calcium influx controlled by the intracellular Ca 2+ stores. On st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572ce7884dd7edb0ab5facb355961d84
https://doi.org/10.1161/atvbaha.117.310139
https://doi.org/10.1161/atvbaha.117.310139
Autor:
Jean-Philippe Rosa, Eliane Berrou, Regis Bobe, Ziane Elaib, Jean-Claude Bordet, Frédéric Adam, Nicolas Prévost, Marijke Bryckaert
Publikováno v:
Blood. 128:1129-1138
The role of the sarco-endoplasmic reticulum calcium (Ca(2+)) adenosine triphosphatase (ATPase) 3 (SERCA3) in platelet physiology remains poorly understood. Here, we show that SERCA3 knockout (SERCA3(-/-)) mice exhibit prolonged tail bleeding time and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ee83984b9ae22ce7874bd69c0c1f4d0
https://doi.org/10.1182/blood-2015-10-678383
https://doi.org/10.1182/blood-2015-10-678383
Autor:
Jose J, Lopez, Letizia, Albarrán, Isaac, Jardín, Jose, Sanchez-Collado, Pedro C, Redondo, Nuria, Bermejo, Regis, Bobe, Tarik, Smani, Juan A, Rosado
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 38(2)
Here, we provide evidence for the role of FLNA (filamin A) in the modulation of store-operated calcium entry (SOCE).SOCE is a major mechanism for calcium influx controlled by the intracellular CaOur results indicate that FLNA modulates SOCE and then
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::686324bc6d72732310a6cab4d10392e4
https://pubmed.ncbi.nlm.nih.gov/29284605
https://pubmed.ncbi.nlm.nih.gov/29284605
Autor:
Evangelia G. Kranias, Regis Bobe, Irene C. Turnbull, Nathalie Mougenot, Anne-Marie Lompré, Alexandra S. Ross, Lifan Liang, Roger J. Hajjar, Jiqiu Chen, Elise Merlet, Larissa Lipskaia, Fabrice Atassi, Ioannis Karakikes, Sima T. Tarzami, Lahouaria Hadri, Dongtaq Jeong, Jason C. Kovacic, Jose J. Lopez
Publikováno v:
Circulation. 129:773-785
Background— Phenotypic modulation or switching of vascular smooth muscle cells from a contractile/quiescent to a proliferative/synthetic phenotype plays a key role in vascular proliferative disorders such as atherosclerosis and restenosis. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b20a904727151517b034377e2e7f29e
https://doi.org/10.1161/circulationaha.113.002565
https://doi.org/10.1161/circulationaha.113.002565