Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Regis Bobe"'
Autor:
Elisa Rossi, Alexandre Kauskot, François Saller, Elisa Frezza, Sonia Poirault-Chassac, Anna Lokajczyk, Pierre Bourdoncle, Bruno Saubaméa, Pascale Gaussem, Miguel Pericacho, Regis Bobe, Christilla Bachelot-Loza, Samuela Pasquali, Carmelo Bernabeu, David M. Smadja
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8837 (2021)
Endoglin (Eng) is an endothelial cell (EC) transmembrane glycoprotein involved in adhesion and angiogenesis. Eng mutations result in vessel abnormalities as observed in hereditary hemorrhagic telangiectasia of type 1. The role of Eng was investigated
Externí odkaz:
https://doaj.org/article/6a17db54d6434dae852e315cf67bc16c
Autor:
Luigi Maione, Frederique Albarel, Philippe Bouchard, Megan Gallant, Colleen A Flanagan, Regis Bobe, Joelle Cohen-Tannoudji, Rosario Pivonello, Annamaria Colao, Thierry Brue, Robert P Millar, Marc Lombes, Jacques Young, Anne Guiochon-Mantel, Jerome Bouligand
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69616 (2013)
Normosmic congenital hypogonadotropic hypogonadism (nCHH) is a rare reproductive disease leading to lack of puberty and infertility. Loss-of-function mutations of GNRH1 gene are a very rare cause of autosomal recessive nCHH. R31C GNRH1 is the only mi
Externí odkaz:
https://doaj.org/article/a9255ab17ae24c32ade14102c14476b2
Autor:
Luigi Maione, Frederique Albarel, Philippe Bouchard, Megan Gallant, Colleen A. Flanagan, Regis Bobe, Joelle Cohen-Tannoudji, Rosario Pivonello, Annamaria Colao, Thierry Brue, Robert P. Millar, Marc Lombes, Jacques Young, Anne Guiochon-Mantel, Jerome Bouligand
Publikováno v:
PLoS ONE, Vol 8, Iss 8 (2013)
Externí odkaz:
https://doaj.org/article/82a2395d5f8d4a8fbb72e52719c7436b
Autor:
Alain Stepanian, Simon Msika, Aurélie Kondratieff, Cécile V. Denis, Dominique de Prost, Muriel Coupaye, Yann Becker, Laurence Salomon, Kevin Zuber, Regis Bobe, Jean-Philippe Rosa, Jose J. Lopez, Christelle Repérant, Marion Pépin, Ziane Elaib
Publikováno v:
Thrombosis and Haemostasis. 119:384-396
In obesity, platelets are described as hyperactive, mainly based on increased platelet size and presence of pro-thrombotic plasmatic molecules. We explored platelet functions, including calcium signalling in obesity, and the effect of weight loss. We
Autor:
Cécile V. Denis, Frédéric Adam, Delphine Borgel, Regis Bobe, Jean-Philippe Rosa, Ziane Elaib, Miao Feng, Marijke Bryckaert
Publikováno v:
Circulation Research
Circulation Research, American Heart Association, 2020, 127 (7), pp.e166-e183. ⟨10.1161/CIRCRESAHA.119.316090⟩
Circulation Research, American Heart Association, 2020, 127 (7), pp.e166-e183. ⟨10.1161/CIRCRESAHA.119.316090⟩
Rationale: Ca 2+ signaling is a key and ubiquitous actor of cell organization and its modulation controls many cellular responses. SERCAs (sarco-endoplasmic reticulum Ca 2+ -ATPases) pump Ca 2+ into internal stores that play a major role in the cytos
Autor:
Florent Raffin, Regis Bobe, François Saller, François-Xavier Boittin, Kathia Beddek, Diane Riccobono, Delphine Borgel
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
The Transient Receptor Potential Vanilloid 4 (TRPV4) of endothelial cells contributes to many important functions including the regulation of Ca2+ homeostasis, cell volume, endothelial barrier permeability, and smooth muscle tone. However, its role i
Autor:
Jose Sanchez-Collado, Regis Bobe, Jose J. Lopez, Juan A. Rosado, Isaac Jardín, Letizia Albarran, Tarik Smani, Nuria Bermejo, Pedro C. Redondo
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:386-397
Objective— Here, we provide evidence for the role of FLNA (filamin A) in the modulation of store-operated calcium entry (SOCE). Approach and Results— SOCE is a major mechanism for calcium influx controlled by the intracellular Ca 2+ stores. On st
Autor:
Jean-Philippe Rosa, Eliane Berrou, Regis Bobe, Ziane Elaib, Jean-Claude Bordet, Frédéric Adam, Nicolas Prévost, Marijke Bryckaert
Publikováno v:
Blood. 128:1129-1138
The role of the sarco-endoplasmic reticulum calcium (Ca(2+)) adenosine triphosphatase (ATPase) 3 (SERCA3) in platelet physiology remains poorly understood. Here, we show that SERCA3 knockout (SERCA3(-/-)) mice exhibit prolonged tail bleeding time and
Autor:
François-Xavier Boittin, Nathalie Guitard, Maeliss Toth, Diane Riccobono, Hélène Théry, Régis Bobe
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2269 (2024)
High-dose irradiation can trigger numerous endothelial dysfunctions, including apoptosis, the overexpression of adhesion molecules, and alteration of adherens junctions. Altogether, these endothelial dysfunctions contribute to the development of tiss
Externí odkaz:
https://doaj.org/article/0171eb9a749547ad9814ce300f6836cf
Autor:
Jose J, Lopez, Letizia, Albarrán, Isaac, Jardín, Jose, Sanchez-Collado, Pedro C, Redondo, Nuria, Bermejo, Regis, Bobe, Tarik, Smani, Juan A, Rosado
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 38(2)
Here, we provide evidence for the role of FLNA (filamin A) in the modulation of store-operated calcium entry (SOCE).SOCE is a major mechanism for calcium influx controlled by the intracellular CaOur results indicate that FLNA modulates SOCE and then