Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Regis, Denay"'
Autor:
Daniel Kweku Anokwah, Pascal Furet, Regis Denay, Dorina Kotoni, Dominique Bixel, Thomas Allmendinger
Publikováno v:
Helvetica Chimica Acta. 105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32dce8f3ccf8ef566be71955c94fd378
https://doi.org/10.1002/hlca.202100230
https://doi.org/10.1002/hlca.202100230
Autor:
Anna Vulpetti, Andrew Proudfoot, Andreas Lingel, Christelle Henry, Andreas O. Frank, Regis Denay, Tony Reinsperger, Alexandra Frommlet, Ulrich Hommel, Burkhard Luy, Alvar D. Gossert
Publikováno v:
Angewandte Chemie International Edition. 59:14809-14817
Fragment-based lead discovery has become a fundamental approach to identify ligands that efficiently interact with disease-relevant targets. Among the numerous screening techniques, fluorine-detected NMR has gained popularity owing to its high sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c3d9f862e00337c6d5f95a852d5026
https://doi.org/10.1002/anie.202002463
https://doi.org/10.1002/anie.202002463
Autor:
Greg Mann, Frédéric V. Stanger, Theo Peschke, Kirsten Schroer, Nhat Quang Nguyen Trung, Nathalie Burrer, Franziska Grassinger, Lorenzo Piccioni, Oemer Erdogan, Jeremy Heimburger, Hervé Koehl, Heike Ertle, Regis Denay, Philippe Dreier, Thierry Schlama
Publikováno v:
Tetrahedron Letters. 93:153696
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7e73254b93bf72c9a379de59bb6ebbe
https://doi.org/10.1016/j.tetlet.2022.153696
https://doi.org/10.1016/j.tetlet.2022.153696
Autor:
Alvar Gossert, Anna Vulpetti, Ulrich Hommel, Tony Reinsperger, Alexandra Frommlet, Regis Denay, Andreas Lingel, Andrew Proudfoot, Burkhard Luy, Christelle Henry, Andreas Frank
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d02bc1ed11ec3dbd305694bf60666ed0
https://doi.org/10.1021/scimeetings.0c07139
https://doi.org/10.1021/scimeetings.0c07139
Autor:
Andreas, Lingel, Anna, Vulpetti, Tony, Reinsperger, Andrew, Proudfoot, Regis, Denay, Alexandra, Frommlet, Christelle, Henry, Ulrich, Hommel, Alvar D, Gossert, Burkhard, Luy, Andreas O, Frank
Publikováno v:
Angewandte Chemie (International ed. in English). 59(35)
Fragment-based lead discovery has become a fundamental approach to identify ligands that efficiently interact with disease-relevant targets. Among the numerous screening techniques, fluorine-detected NMR has gained popularity owing to its high sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4862930872d9705620c4b086ef948d22
https://pubmed.ncbi.nlm.nih.gov/32363632
https://pubmed.ncbi.nlm.nih.gov/32363632
Autor:
Serge Moss, Günter Bovermann, Regis Denay, Julien France, Christian Guenat, Lukas Oberer, Monique Ponelle, Harald Schröder
Publikováno v:
CHIMIA, Vol 61, Iss 6 (2007)
The procedure of structure elucidation of natural products at Novartis is discussed. Structure elucidation in an industrial environment has to be time efficient, which is achieved by an optimized workflow and a close integration of all analytical met
Externí odkaz:
https://doaj.org/article/8b3e82858a104bf49df4faba8d86470b
Autor:
Christelle Henry, Tony Reinsperger, Andreas O. Frank, Anna Vulpetti, Regis Denay, Andreas Lingel, Burkhard Luy, Alexandra Frommlet, Alvar D. Gossert, Andrew Proudfoot, Ulrich Hommel
Publikováno v:
Angewandte Chemie International Edition. 59:14698-14698
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1453755540486b7f1307af2f72d7f509
https://doi.org/10.1002/anie.202009848
https://doi.org/10.1002/anie.202009848
Autor:
Feng Sun, David Thomas Parker, Friedrich Schuerch, Silvio Roggo, Xiaolin Li, Zachary Kevin Sweeney, Li Cao, Nicole Meier, Bernard Riss, Christian Guenat, Wei Li, Zhaobo Gao, Jiping Fu, Jibin Zhao, Subramanian Karur, Wang Ruidong, Andrew H. Weiss, Regis Denay, Alexey Rivkin, Su Xu, Harald Schroeder, Michael Paul Capparelli, Simon Ng, Quanbing Wu, Xin Xiong, Weikuan Li, Wosenu Mergo, Christopher Becker, Robert Lowell Simmons, Amy Lu, Gai Yu, Wenjian Xu, Peichao Lu, Nicolas Wenger, Christian Zürcher, Thomas Lochmann, Meiliana Tjandra, Alexandre Luneau, Hongyong Kim, Aregahegn Yifru, Yunshan Peng, Fabrice Gallou, Jianguang Zhou, Roger Aki Fujimoto, Michael Wang
Publikováno v:
Bioorganicmedicinal chemistry. 26(4)
Synthetic modification of cyclosporin A at P3-P4 positions led to the discovery of NIM258, a next generation cyclophilin inhibitor with excellent anti-hepatitis C virus potency, with decreased transporter inhibition, and pharmacokinetics suitable for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e52dd8f35f84c5e846138d1c4df359
https://pubmed.ncbi.nlm.nih.gov/28919180
https://pubmed.ncbi.nlm.nih.gov/28919180
Autor:
Stephanie Guerro-Lagasse, Andreas Marzinzik, Sandra W. Cowan-Jacob, Linda Hinh, César Fernández, Julia Klopp, Alexei S. Karpov, Sabina Pecchi, Inga Galuba, Henrik Möbitz, Sylvia Ma, Kevin Shoemaker, Payman Amiri, Marie-Helene Bellance, Werner Breitenstein, Joerg Trappe, Dylan Daniel, Gabriele Rummel, Mika Lindvall, Charles Voliva, Cornelia Bellamacina, Wolfgang Jahnke, Doriano Fabbro, Sascha Gutmann, Albert Lai, Regis Denay
The discovery of inhibitors targeting novel allosteric kinase sites is very challenging. Such compounds, however, once identified could offer exquisite levels of selectivity across the kinome. Herein we report our structure-based optimization strateg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d26e497abbd399d9317b94bae55a6f
https://europepmc.org/articles/PMC4499825/
https://europepmc.org/articles/PMC4499825/
Autor:
Riccardo Canova, Regis Denay, Guido Koch, Michele Dattilo, David Orain, Edgar Klöppner, Rudolf K. A. Giger
Publikováno v:
Synlett. 2002:1443-1446
The solution and solid-phase syntheses of a 3,9-diazabi-cyclo[3.3.1]non-6-en-2-one have been realised via sequential Dakin-West/Pictet-Spengler reactions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dddc6c15f6278b4ee752714837b3d390
https://doi.org/10.1055/s-2002-33553
https://doi.org/10.1055/s-2002-33553