Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Regine Gaetje"'
Autor:
Thomas Karn, Lajos Pusztai, Uwe Holtrich, Takayuki Iwamoto, Christine Y Shiang, Marcus Schmidt, Volkmar Müller, Christine Solbach, Regine Gaetje, Lars Hanker, Andre Ahr, Cornelia Liedtke, Eugen Ruckhäberle, Manfred Kaufmann, Achim Rody
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28403 (2011)
BackgroundCurrent prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers. The identification of prognostic signatures from TNBC cohorts was limited in the past due to
Externí odkaz:
https://doaj.org/article/11e2ff571171401c9ba3fb6bd4809bd3
Autor:
Manfred Kaufmann, Thomas Karn, Christine Solbach, Andre Ahr, Dirk Metzler, Eugen Ruckhäberle, Raihanatou Diallo-Danebrock, Sibylle Loibl, Gunter von Minckwitz, Knut Engels, Mathias Gehrmann, Regine Gaetje, Uwe Holtrich, Achim Rody
8 Supplementary Figures and 2 Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755fabe4ce53ff525281496c9841044c
https://doi.org/10.1158/1078-0432.22441921
https://doi.org/10.1158/1078-0432.22441921
Autor:
Manfred Kaufmann, Thomas Karn, Christine Solbach, Andre Ahr, Dirk Metzler, Eugen Ruckhäberle, Raihanatou Diallo-Danebrock, Sibylle Loibl, Gunter von Minckwitz, Knut Engels, Mathias Gehrmann, Regine Gaetje, Uwe Holtrich, Achim Rody
Purpose: A common characteristic of mammary carcinomas is an inverse relationship between the estrogen receptor (ER) status and the proliferative activity of the tumor. Yet, a subset of ER-positive breast cancers is characterized by a high proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2677bf6841d0d104aabaf5f3ccd2c50a
https://doi.org/10.1158/1078-0432.c.6518788.v1
https://doi.org/10.1158/1078-0432.c.6518788.v1
Autor:
Manfred Kaufmann, E. Ruckhaeberle, Regine Gaetje, Knut Engels, U. Holtrich, Achim Rody, Thomas Karn
Publikováno v:
Geburtshilfe und Frauenheilkunde. 69:935-939
Sphingolipids are important constituents of cell membranes, which play key roles as regulatory molecules for various cellular functions. Sphingosine-1-phosphate produced by sphingosine kinase 1 (SPHK1) promotes cell proliferation, regulates angiogene
Autor:
Lars Hanker, Eugen Ruckhäberle, U. Holtrich, F. Pobitschka, Achim Rody, M. Gehrmann, C. Solbach, Thomas Karn, Regine Gaetje, Manfred Kaufmann, A. Ahr
Publikováno v:
Geburtshilfe und Frauenheilkunde. 68:1171-1177
BACKGROUND: Many prognostic and predictive multigene signatures have been established in breast cancer patients. For treatment decision the assessment of individual prognosis is essential. The choice of specific therapy is basically driven by empiric
Autor:
Manfred Kaufmann, E. Ruckhaeberle, Regine Gaetje, Lars Hanker, Achim Rody, Uwe Holtrich, Thomas Karn
Publikováno v:
European Journal of Cancer. 44:1789-1792
Reprogramming of human somatic cells into pluripotent cell types gives insight in the pathophysiology of diseases. We analysed genes recently shown to be differentially expressed in induced pluripotent stem cells (iPS) in 95 breast cancer samples. Th
Publikováno v:
Geburtshilfe und Frauenheilkunde. 68:801-804
Cytokeratins are a multigene family of polypeptides expressed in distinct combinations along the various routes of epithelial differentiation. In endometrial cancer and cervical intraepithelial neoplasia/cervical squamous cell carcinoma, the expressi
Publikováno v:
Geburtshilfe und Frauenheilkunde. 68:487-491
Due to the high incidence of uterine leiomyomas, various aspects involved in the treatment of the condition are extremely important. Many treatment methods are already long established, but there are important new findings that are of relevance for e
Autor:
Regine Gaetje, Stefan Kissler, Katherina Kourtis, Eva Cikrit, Uwe Holtrich, Achim Rody, Knut Engels, Thomas Karn, Manfred Kaufmann
Publikováno v:
Gynecological Endocrinology. 23:567-573
The metalloproteinases (MMPs) are a family of proteolytic enzymes involved in tissue remodeling and cell migration. Endometrial tissue remodeling proceeds during the menstrual cycle and requires a temporary and spatially balanced expression of severa
Publikováno v:
Zentralblatt für Gynäkologie. 128:196-201
Bleeding disorders are one of the most frequent gynecological problems. The causes of bleeding disorders, and their frequency in particular, vary depending on the age of the woman affected. In premenopause and perimenopause, the most frequent causes