Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Regine Bernhard"'
Autor:
Masoud Nasri, Malte Ritter, Perihan Mir, Benjamin Dannenmann, Narges Aghaallaei, Diana Amend, Vahagn Makaryan, Yun Xu, Breanna Fletcher, Regine Bernhard, Ingeborg Steiert, Karin Hahnel, Jürgen Berger, Iris Koch, Brigitte Sailer, Katharina Hipp, Cornelia Zeidler, Maksim Klimiankou, Baubak Bajoghli, David C. Dale, Karl Welte, Julia Skokowa
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
A Autosomal-dominant ELANE mutations are the most common cause of severe congenital neutropenia. Although the majority of congenital neutropenia patients respond to daily granulocyte colony stimulating factor, approximately 15 % do not respond to thi
Externí odkaz:
https://doaj.org/article/69e87326290b4238bf136d667edcfb2f
Autor:
Benjamin Dannenmann, Azadeh Zahabi, Perihan Mir, Benedikt Oswald, Regine Bernhard, Maksim Klimiankou, Tatsuya Morishima, Klaus Schulze-Osthoff, Cornelia Zeidler, Lothar Kanz, Nico Lachmann, Thomas Moritz, Karl Welte, Julia Skokowa
Publikováno v:
Experimental Hematology. 114:61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ae79005c0a1233f16f48033e9cd744e
https://doi.org/10.1016/j.exphem.2022.07.302
https://doi.org/10.1016/j.exphem.2022.07.302
Autor:
Karl Welte, Iris Koch, Malte U Ritter, Baubak Bajoghli, Breanna Fletcher, Vahagn Makaryan, Katharina Hipp, Narges Aghaallaei, Julia Skokowa, Regine Bernhard, Yun Xu, Perihan Mir, Ingeborg Steiert, Benjamin Dannenmann, Jürgen Berger, Masoud Nasri, Diana Amend, Cornelia Zeidler, David C. Dale, Maksim Klimiankou, Brigitte Sailer, Karin Hähnel
Publikováno v:
Haematologica. 105:598-609
A Autosomal-dominant ELANE mutations are the most common cause of severe congenital neutropenia. Although the majority of congenital neutropenia patients respond to daily granulocyte colony stimulating factor, approximately 15 % do not respond to thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b05e13dbbcc475c3edc42e05d9dd18d
https://doi.org/10.3324/haematol.2019.221804
https://doi.org/10.3324/haematol.2019.221804
Autor:
Malte U Ritter, Julia Skokowa, Maksim Klimiankou, Cornelia Zeidler, Karl Welte, Masoud Nasri, Benjamin Dannenmann, Benedikt Oswald, Regine Bernhard
Publikováno v:
Blood. 136:23-24
Co-acquisition of CSF3R and RUNX1 mutations is the most frequent combination of acquired genetic abnormalities found in AML and MDS cases associated with severe congenital neutropenia (CN). Using the iPSC-based model for CN-associated leukemia, we co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4cdaaf40b00a3df1f1a8e1631cf9617
https://doi.org/10.1182/blood-2020-142524
https://doi.org/10.1182/blood-2020-142524
Autor:
Masoud, Nasri, Malte, Ritter, Perihan, Mir, Benjamin, Dannenmann, Narges, Aghaallaei, Diana, Amend, Vahagn, Makaryan, Yun, Xu, Breanna, Fletcher, Regine, Bernhard, Ingeborg, Steiert, Karin, Hahnel, Jürgen, Berger, Iris, Koch, Brigitte, Sailer, Katharina, Hipp, Cornelia, Zeidler, Maksim, Klimiankou, Baubak, Bajoghli, David C, Dale, Karl, Welte, Julia, Skokowa
Publikováno v:
Haematologica
A Autosomal-dominant ELANE mutations are the most common cause of severe congenital neutropenia. Although the majority of congenital neutropenia patients respond to daily granulocyte colony stimulating factor, approximately 15 % do not respond to thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::978ea7aa7b7e29b610c4c8c9c0f743b1
https://pubmed.ncbi.nlm.nih.gov/31248972
https://pubmed.ncbi.nlm.nih.gov/31248972
Autor:
Diana Amend, Julia Skokowa, Masoud Nasri, Maksim Klimiankou, Jeremy Haaf, Karl Welte, Regine Bernhard, Benjamin Secker, Malte U Ritter, Perihan Mir, Benjamin Dannenmann, Cornelia Zeidler, Ingeborg Steiert
Publikováno v:
Blood. 136:22-22
Patients with the rare pre-leukemia bone marrow failure syndrome severe congenital neutropenia (CN) have markedly reduced numbers of neutrophils in peripheral blood ( Here, we describe for the first time the application of CRISPR/Cas9 gene-editing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3f417db3ca3ad4392abd8f34c157075
https://doi.org/10.1182/blood-2020-140260
https://doi.org/10.1182/blood-2020-140260
Autor:
Benjamin, Dannenmann, Azadeh, Zahabi, Perihan, Mir, Benedikt, Oswald, Regine, Bernhard, Maksim, Klimiankou, Tatsuya, Morishima, Klaus, Schulze-Osthoff, Cornelia, Zeidler, Lothar, Kanz, Nico, Lachmann, Thomas, Moritz, Karl, Welte, Julia, Skokowa
Publikováno v:
Experimental hematology. 71
We describe the establishment of an embryoid-body-based protocol for hematopoietic/myeloid differentiation of human induced pluripotent stem cells that allows the generation of CD34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13f4036ef48561845b7d43bf15b5d3c8
https://pubmed.ncbi.nlm.nih.gov/35952718
https://pubmed.ncbi.nlm.nih.gov/35952718
Autor:
Julia Skokowa, Benjamin Secker, Baubak Bajoghli, Karin Haehnel, Maksim Klimiankou, Benjamin Dannenmann, Malte U Ritter, Ingeborg Steiert, Karl Welte, Narges Aghaallaei, Masoud Nasri, Cornelia Zeidler, Regine Bernhard
Publikováno v:
Blood. 134:1036-1036
Patients with the rare pre-leukemia bone marrow failure syndrome severe congenital neutropenia (CN) have reduced numbers of neutrophils in peripheral blood ( Up to now, the only curative therapy for CN patients that do not respond to G-CSF or with ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dbf2d7c9195454ae271bf8135cb058d
https://doi.org/10.1182/blood-2019-131708
https://doi.org/10.1182/blood-2019-131708
Autor:
Masoud Nasri, Betuel Findik, Lothar Kanz, Regine Bernhard, Perihan Mir, Maksim Klimiankou, Benjamin Dannenmann, Cornelia Zeidler, Julia Skokowa, Michael A. Rieger, Karl Welte
Publikováno v:
Blood. 132:17-17
The mechanism of maturation arrest of bone marrow myeloid progenitors in severe congenital neutropenia (CN) patients is not fully elucidated. We found, that treatment of healthy individuals with G-CSF induces mRNA expression of GADD45b (Growth Arrest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2498dfff667646bb3b858bb455bd93d7
https://doi.org/10.1182/blood-2018-99-114875
https://doi.org/10.1182/blood-2018-99-114875
Autor:
Lothar Kanz, Azadeh Zahabi, Maksim Klimiankou, Tatsuya Morishima, Cornelia Zeidler, Christian Lindner, Julia Skokowa, Karl Welte, Regine Bernhard, Benjamin Dannenmann
Publikováno v:
Blood. 128:404-404
Severe congenital neutropenia (CN) is a pre-leukemic bone marrow failure syndrome. Recently we reported a high frequency of cooperating RUNX1 and CSF3R mutations in CN patients that developed AML or MDS. Only a combination of these two mutations indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1b715d4a1e580e4a994744561f4b21d
https://doi.org/10.1182/blood.v128.22.404.404
https://doi.org/10.1182/blood.v128.22.404.404