Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Regine, Baur"'
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Valproic acid inhibits proliferation of human coronary vascular cells (SI/MPL-ratio: 0.5): a novel candidate for systemic and local therapy of postinterventional restenosis
Autor: Vinzenz Hombach, Ricarda Krebs, Rainer Voisard, Regine Baur
Publikováno v: Coronary Artery Disease. 21:286-291
OBJECTIVES The branched-chain fatty acid, valproic acid (VPA), is the most commonly used anti-epileptic drug for treating generalized epilepsy. Recently antiproliferative effects of VPA have been described in human cancer cells, and phase I trials fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5bb51c6052d4e4dd875cfb193794d0
https://doi.org/10.1097/mca.0b013e3283349cd7
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2
Effect of Diltiazem and Verapamil on Endothelin Release by Cultured Human Coronary Smooth-Muscle Cells and Endothelial Cells
Autor: Vinzenz Hombach, Cornelia Haug, Andreas Hannekum, Rainer Voisard, Regine Baur, Adolf Gruenert
Publikováno v: Journal of Cardiovascular Pharmacology. 31:S388-S391
Recent data suggest that endothelin (ET) production is enhanced in coronary atherosclerotic lesions. In several studies, an anti-atherosclerotic effect has been attributed to calcium-channel antagonists. This study aimed to investigate whether ET rel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c815e8fa67e620ffac2693ed1eee291
https://doi.org/10.1097/00005344-199800001-00111
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3
A prescreening system for potential antiproliferative agents: implications for local treatment strategies of postangioplasty restenosis
Autor: Peter C. Dartsch, Rainer Voisard, Hans Osterhues, Regine Baur, Vinzenz Hombach, Martin Höher, Seitzer U
Publikováno v: International Journal of Cardiology. 51:15-28
Recent advances in the understanding of the biology of restenosis indicate that it is predominantly caused by a multifactorial stimulation of smooth muscle cell proliferation. The aim of this study was to investigate the in vitro effect of five poten
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a1241f6c9096303ae3175093ed9345
https://doi.org/10.1016/0167-5273(95)02377-9
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4
A coronary porcine organ culture system for studies of postangioplasty cell proliferation
Autor: Hombach, Martin Höher, Jensch, Rainer Voisard, Regine Baur
Publikováno v: Europe PubMed Central
BACKGROUND Restenosis after angioplasty is generally considered to be caused mainly by an increased proliferation of smooth muscle cells, but recently this theory has been questioned. METHODS Fresh hearts of 25 pigs were obtained and the left anterio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7dd9671542539a0e2c6d345d089c4aa
https://doi.org/10.1097/00019501-199508000-00011
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5
Pulsed perfusion in a venous human organ culture model with a Windkessel function (pulsed perfusion venous HOC-model)
Autor: Rainer, Voisard, Emini, Ramiz, Regine, Baur, Iris, Gastrock-Balitsch, Heinrich, Siebeneich, Olaf, Frank, Vinzenz, Hombach, Andreas, Hannekum, Bernd, Schumacher
Publikováno v: Medical science monitor : international medical journal of experimental and clinical research. 16(11)
The effectiveness of human saphenous vein grafting is limited by hyperplasia of the vessel wall. The current paper reports on a pulsed perfused venous human organ culture model (pp-venous HOC-model) with a Windkessel function.Saphenous vein grafts fr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8b4af8d3072a08cc5393e054f5a0019b
https://pubmed.ncbi.nlm.nih.gov/20980955
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6
Low-dose irradiation stimulates TNF-alpha-induced ICAM-1 mRNA expression in human coronary vascular cells
Autor: Rainer, Voisard, Dirk, Wiegmann, Regine, Baur, Vinzenz, Hombach, Joachim, Kamenz
Publikováno v: Medical science monitor : international medical journal of experimental and clinical research. 13(5)
Low-dose irradiation (LDI) is employed to extend the irradiation area in vascular brachytherapy to minimize the edge effect. Stimulation of adhesion molecule 1 (ICAM-1) is one of many mechanisms important in the early stages of atherosclerosis and re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a669421925696e237eab455adb7d4e5
https://pubmed.ncbi.nlm.nih.gov/17476188
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7
A perfused renal human organ culture model: impact of monocyte attack
Autor: Rainer, Voisard, Regine, Baur, Tina, Herter, Uwe, Krüger, Jürgen, Breul, Lutz, Keller, Vinzenz, Hombach
Publikováno v: Medical science monitor : international medical journal of experimental and clinical research. 13(2)
Key processes of atherosclerosis and restenosis are triggered and/or modified by the contact of human monocytes (MCs) with the inner layers of the arterial vessel wall. This is the first report on monocyte attack in a perfused renal human organ cultu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2c15f325143d2e750d4786e8afc89bf5
https://pubmed.ncbi.nlm.nih.gov/17261987
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8
Sirolimus inhibits key events of restenosis in vitro/ex vivo: evaluation of the clinical relevance of the data by SI/MPL- and SI/DES-ratios
Autor: Regine Baur, Felicitas Fahlisch, Jürgen Gschwendt, Jürgen Braun, Joachim Kamenz, Svenja Zellmann, Fabian Müller, Lutz von Müller, Vinzenz Hombach, Margaratis Kountides, Rainer Voisard
Publikováno v: BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, Vol 7, Iss 1, p 15 (2007)
Background Sirolimus (SRL, Rapamycin) has been used successfully to inhibit restenosis both in drug eluting stents (DES) and after systemic application. The current study reports on the effects of SRL in various human in vitro/ex vivo models and eval
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4532294c1a9565dfeb11e82e5561619d
https://pubmed.ncbi.nlm.nih.gov/17498286
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9
Edge restenosis: impact of low dose irradiation on cell proliferation and ICAM-1 expression
Autor: Tina Herter, Rainer Voisard, Regine Baur, Andreas Hannekum, Jochen Höb, Vinzenz Hombach
Publikováno v: BMC Cardiovascular Disorders, Vol 6, Iss 1, p 32 (2006)
BMC Cardiovascular Disorders
Background Low dose irradiation (LDI) of uninjured segments is the consequence of the suggestion of many authors to extend the irradiation area in vascular brachytherapy to minimize the edge effect. Atherosclerosis is a general disease and the uninju
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9338ffac1d83d2d5fe8d07fbab2b05d3
https://doi.org/10.1186/1471-2261-6-32
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10
Effects of abciximab on key pattern of human coronary restenosis in vitro: impact of the SI/MPL-ratio
Autor: Vinzenz Hombach, Rainer Voisard, Regine Baur, Lutz von Müller, Mustafa Alan
Publikováno v: BMC Cardiovascular Disorders, Vol 6, Iss 1, p 14 (2006)
BMC Cardiovascular Disorders
Background The significant reduction of angiographic restenosis rates in the ISAR-SWEET study (intracoronary stenting and antithrombotic regimen: is abciximab a superior way to eliminate elevated thrombotic risk in diabetes) raises the question of wh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd25e3e9b1763bd6db9682e14362438
http://www.biomedcentral.com/1471-2261/6/14
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