Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Reginald Delarosa"'
Autor:
Peter S. Dragovich, Sheila Ulufatu, John S. Wai, James Lee, Reginald Delarosa, Carl Ng, Zijin Xu, Chunjiao Chen, Shang-Fan Yu, S. Cyrus Khojasteh, Gail Lewis Phillips, Rebecca K. Rowntree, Keyang Xu, Aimee Fourie-O'Donohue, Zhonghua Pei, Isabel Figueroa, Liling Liu, Josefa dela Cruz-Chuh, Jiawei Lu, Jun Guo, Weiwei Jin, Jing Wang, Jinhua Chen, Eva Lin, Nicola J. Stagg, David Stokoe, Scott E. Martin, Trung Nguyen, Donglu Zhang, Hui Yao, Guangmin Li, Rachana Ohri, Thomas H. Pillow, Katherine R. Kozak, Brandon Latifi, Yuzhong Deng, Vishal Verma
Publikováno v:
Molecular Pharmaceutics. 15:3979-3996
A number of cytotoxic pyrrolobenzodiazepine (PBD) monomers containing various disulfide-based prodrugs were evaluated for their ability to undergo activation (disulfide cleavage) in vitro in the presence of either glutathione (GSH) or cysteine (Cys).
Autor:
Rich Erickson, An Song, Kun Peng, Robert Hendricks, Maya Leabman, Luna Liu, Saloumeh K Fischer, Surinder Kaur, Keyang Xu, Reginald Delarosa, Nageshwar Budha
Publikováno v:
mAbs. 6:1500-1508
RG7652 is a human immunoglobulin 1 (IgG1) monoclonal antibody (mAb) targeting proprotein convertase subtilisin/kexin type 9 (PCSK9) and is designed for the treatment of hypercholesterolemia. A target-binding enzyme-linked immunosorbent assay (ELISA)
Autor:
Reginald Delarosa, Rich Erickson, Houston Gilbert, An Song, Daniel Coleman, Bert Gunter, Saloumeh K Fischer, Kyra J. Cowan, Brian Sue
Publikováno v:
Bioanalysis. 4:2127-2139
Background: Design of experiments (DOE) is a systematic approach to assess the effects of many factors on a response of an assay. This paper provides a case study whereby DOE was successfully utilized to evaluate robustness parameters for a ligand-bi
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 84