Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Regina-Maria Kolaitis"'
Autor:
Youngdae Gwon, Regina-Maria Kolaitis, Brian A. Maxwell, Hong Joo Kim, Peipei Zhang, J. Paul Taylor
Publikováno v:
Science. 372
INTRODUCTION Stress granules are dynamic structures composed of RNA and protein that arise in the cytoplasm in response to a variety of stressors. These structures form via liquid-liquid phase separation and are usually promptly disassembled after th
Autor:
Regina-Maria Kolaitis, Peipei Zhang, Brian A. Maxwell, Hong Joo Kim, Youngdae Gwon, Taylor Jp
Stress granules are dynamic, reversible condensates composed of RNA and protein that assemble in response to a variety of stressors and are normally disassembled after stress is removed. Whereas the composition of stress granules and the mechanisms u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb8d6624f80e4d427ee4e9a48d8878df
https://doi.org/10.1101/2021.04.22.440930
https://doi.org/10.1101/2021.04.22.440930
Autor:
Peipei Zhang, Yuxin Li, Jiyang Yu, Regina-Maria Kolaitis, Jinjun Wu, Peiguo Yang, Cécile Mathieu, Ugur Yurtsever, Qingfei Pan, Tanja Mittag, James Messing, Hong Joo Kim, Erik W. Martin, J. Paul Taylor, Zemin Yang
Publikováno v:
Cell
The mechanisms underlying ribonucleoprotein (RNP) granule assembly, including the basis for establishing and maintaining RNP granules with distinct composition, are unknown. One prominent type of RNP granule is the stress granule (SG), a dynamic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45227935c9d9cdd4377fa940547088e
https://europepmc.org/articles/PMC7448383/
https://europepmc.org/articles/PMC7448383/
Autor:
Gilbert G. Privé, Jihun Lee, Sophia A. Kenrick, Tanja Mittag, Michal Sharon, Peter Schuck, Melissa R. Marzahn, Suresh Marada, Huaying Zhao, Wesley J. Errington, Regina-Maria Kolaitis, Stacey K. Ogden, Gili Ben-Nissan, Stanley Pounds, Jennifer L. Peters, Amanda Nourse, J. Paul Taylor
Publikováno v:
The EMBO Journal
Membrane‐less organelles in cells are large, dynamic protein/protein or protein/RNA assemblies that have been reported in some cases to have liquid droplet properties. However, the molecular interactions underlying the recruitment of components are
Autor:
J. Paul Taylor, Ichiro Yabe, Eric D. Ross, Mishie Tanino, Songqing Li, Hidenao Sasaki, Shinya Tanaka, Regina-Maria Kolaitis, Brian D. Freibaum, Hong Joo Kim, Anderson P. Kanagaraj, Peipei Zhang, Nam Chul Kim, Amandine Molliex
Publikováno v:
Human Molecular Genetics. 25:936-950
Adult-onset inherited myopathies with similar pathological features, including hereditary inclusion body myopathy (hIBM) and limb-girdle muscular dystrophy (LGMD), are a genetically heterogeneous group of muscle diseases. It is unclear whether these
Autor:
Erica G. Colicino, Regina-Maria Kolaitis, Carlos A. Castañeda, Heidi Hehnly, Brian Martyniak, J. Paul Taylor, Hong Joo Kim, Kevin J. O'Donovan, Thuy P. Dao
Under stress, certain eukaryotic proteins and RNA assemble to form membraneless organelles known as stress granules. The most well-studied stress granule components are RNA-binding proteins that undergo liquid-liquid phase separation (LLPS) into prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce5e56ac51db6bfaee675791efdb971
https://europepmc.org/articles/PMC6181577/
https://europepmc.org/articles/PMC6181577/
Autor:
Philip Van Damme, Thomas Vercruysse, Paul A. Anderson, Elke Bogaert, Denes Kovacs, Pieter Baatsen, Veronica H Ryan, J. Paul Taylor, Mathias De Decker, Frederic Rousseau, Albert Konijnenberg, Nicolas L. Fawzi, Dirk Daelemans, Mainak Guharoy, Evy Timmerman, Regina-Maria Kolaitis, Peter Tompa, Abigail M. Janke, Frank Sobott, Nancy Kedersha, Joost Schymkowitz, Alex Volkov, Wim Robberecht, Francis Impens, Tom Jaspers, Steven Boeynaems, Ludo Van Den Bosch
Publikováno v:
Molecular Cell
Molecular cell
BASE-Bielefeld Academic Search Engine
MOLECULAR CELL
Molecular cell
BASE-Bielefeld Academic Search Engine
MOLECULAR CELL
Summary Liquid-liquid phase separation (LLPS) of RNA-binding proteins plays an important role in the formation of multiple membrane-less organelles involved in RNA metabolism, including stress granules. Defects in stress granule homeostasis constitut
Autor:
Hong Joo Kim, Junmin Peng, Regina-Maria Kolaitis, Diana M. Mitrea, Nam Chul Kim, Jaclyn A Cika, Jennifer Moore, Timothy I. Shaw, James Messing, Peipei Zhang, J. Paul Taylor, Maura Coughlin, Richard W. Kriwacki, Brian A. Maxwell, Jamshid Temirov, Bing Bai, Kyung-Ha Lee, Brian D. Freibaum, Amandine Molliex, Mohona Sarkar
Expansion of a hexanucleotide repeat GGGGCC (G4C2) in C9ORF72 is the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Transcripts carrying (G4C2) expansions undergo unconventional, non-ATG-dependent translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2d2c40828e82773e97513484507e19
https://europepmc.org/articles/PMC5079111/
https://europepmc.org/articles/PMC5079111/
Publikováno v:
Open Life Sciences, Vol 7, Iss 2, Pp 185-191 (2012)
Protein kinase CK2 is a highly conserved Ser/Thr protein kinase involved in cell cycle control, transcription, signal transduction and cell proliferation. It is upregulated in several diseases and by oxidative stress. CK2 is generally composed of two
Autor:
Sophia Kouyanou-Koutsoukou, Regina-Maria Kolaitis, Konstantina Thanopoulou, Andrea Baier, Ryszard Szyszka, Evanthia Maniatopoulou
Publikováno v:
Molecular and Cellular Biochemistry. 356:261-267
The Mediterranean fruit fly Ceratitis capitata is an insect capable of wreaking extensive damage to a wide range of fruit crops. Protein kinase CK2 is a ubiquitous Ser/Thr kinase that is highly conserved among eukaryotes; it is a heterotetramer compo