Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Regina Voglauer"'
Autor:
Ingeborg Stelzer, Johannes Grillari, Elisabeth Schraml, Regina Voglauer, Klaus Fortschegger, Konrad Schauenstein, Maria Sibilia
Publikováno v:
Stem Cells and Development. 17:355-366
The quality of hematopoietic stem cells (HSCs) is essentially defined by two characteristics, i.e., multilineage differentiation and self-renewal capacity. Thus, it is of high priority to clarify mechanisms that regulate these functions and to unders
Autor:
Alfred Beham, Hermann Katinger, Bruno Niederle, Regina Voglauer, Josef Friedl, Guido Stadler, Berthold Streubel, Roswitha Pfragner, Johannes Grillari, Anton Stift, Michael Gnant, Matthias Wieser
Publikováno v:
European Journal of Cancer. 44:866-875
Maintenance of telomere length has been reported to be an absolute requirement for unlimited growth of human tumour cells and in about 85% of cases, this is achieved by reactivation of telomerase, the enzyme that elongates telomeres. Only in rare cas
Publikováno v:
Nucleic Acids Research
Impaired DNA damage repair, especially deficient transcription-coupled nucleotide excision repair, leads to segmental progeroid syndromes in human patients as well as in rodent models. Furthermore, DNA double-strand break signalling has been pinpoint
Autor:
Regina Voglauer, Hermann Katinger, Bettina Wagner, Klaus Fortschegger, Maria Sibilia, Johannes Grillari
Publikováno v:
Molecular and Cellular Biology. 27:3123-3130
SNEV (Prp19, Pso4, NMP200) is a nuclear matrix protein known to be involved in pre-mRNA splicing, ubiquitylation, and DNA repair. In human umbilical vein endothelial cells, SNEV overexpression delayed the onset of replicative senescence. Here we anal
Publikováno v:
Journal of Biological Chemistry. 282:5984-5990
Peptide O-xylosyltransferase (EC 2.4.2.26) is the first enzyme required for the generation of chondroitin and heparan sulfate glycosaminoglycan chains of proteoglycans. Cloning of cDNAs has previously shown that, whereas invertebrates generally have
Autor:
Christine Fehrer, Gerald Pfister, Matthias Wieser, Regina Voglauer, Daniel Cioca, Beatrix Grubeck-Loebenstein, Regina Brunauer, Günter Lepperdinger
Publikováno v:
Experimental Gerontology. 41:648-651
The length of telomeres is believed to critically influence cellular aging processes and disease development. In order to reliably monitor telomere length and the corresponding cellular telomerase activity by optimized procedures, either based on flo
Autor:
Klaus Fortschegger, Martina Wei-Fen Chang, Pidder Jansen-Dürr, Günter Lepperdinger, A. Breitwieser, B. Fitzky, Hermann Unterluggauer, S. Ressler, Regina Voglauer, Barbara Hampel, W. Sommergruber, Johannes Grillari
Publikováno v:
Experimental Gerontology. 41:474-481
A convenient way to study processes of aging in distinct human tissues consists of a molecular analysis of cells from the tissue in question, that were explanted and grown in vitro until they reach senescence. Using human umbilical vein endothelial c
Autor:
Boris Ferko, Hermann Katinger, Renate Kunert, Johannes Grillari, Regina Voglauer, Nicole Borth, Ernst Böhm, Wolfgang Ernst, Stefan Gross
Publikováno v:
Journal of Immunological Methods. 307:13-23
The screening for antigen-specific hybridoma cells with adequate production rates is still a time-, labour- and money-consuming procedure. A reduction in cell culture testing by specifically selecting those fused cells that produce antibody could the
Autor:
Marion Pokar, Hermann Katinger, Janet Chusainow, Angus I. Lamond, Regina Voglauer, Martin Grey, Klaus Fortschegger, Wolfgang Ernst, Johannes Grillari, Guido Stadler, Paul Ajuh, Frank Eisenhaber, Marlies Löscher
Publikováno v:
Nucleic Acids Research
We have isolated the human protein SNEV as downregulated in replicatively senescent cells. Sequence homology to the yeast splicing factor Prp19 suggested that SNEV might be the orthologue of Prp19 and therefore might also be involved in pre-mRNA spli
Autor:
Andrej Egorov, Regina Voglauer, Hermann Katinger, Sabine Sereinig, Gabriela Stiegler, Martina Kurz, Christian Kittel, Julia Romanova, Boris Ferko
Publikováno v:
Journal of Virology. 79:10672-10677
Engineering of the influenza A virus NS1 protein became an attractive approach to the development of influenza vaccine vectors since it can tolerate large inserts of foreign proteins. However, influenza virus vectors expressing long foreign sequences