Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Regina P Markus"'
Autor:
Rafaella Valete Nunes Paiva, Pedro Henrique de Lima Mondes, Beatriz de Jesus Brandão, Julia Nascimento Sant’Anna, Maria Eduarda Freire dos Santos, Yasmin Muniz Fighera, Luciano Cardoso Santos, Regina P. Markus, Pedro Augusto Carlos Magno Fernandes, Juneo Freitas Silva, Eduardo Koji Tamura
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionThe reproductive system is tightly regulated by environmental and physiological signals. Melatonin, known as the hormone of darkness, plays a crucial role in regulating both the circadian and reproductive systems in mammals. Hypothyroidis
Externí odkaz:
https://doaj.org/article/667a3dfcebcc4a91bc3ab4b5911288f1
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 102, Iss 3, Pp 329-334 (2007)
Plasmodium chabaudi malaria parasite organelles are major elements for ion homeostasis and cellular signaling and also target for antimalarial drugs. By using confocal imaging of intraerythrocytic parasites we demonstrated that the dye acridine orang
Externí odkaz:
https://doaj.org/article/7fad1867a27b44fe8f7bd71a01fca28f
Autor:
Daiane Gil Franco, Regina P Markus
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106332 (2014)
The constitutive activation of nuclear factor-κB (NF-κB), a key transcription factor involved in neuroinflammation, is essential for the survival of neurons in situ and of cerebellar granule cells in culture. Melatonin is known to inhibit the activ
Externí odkaz:
https://doaj.org/article/1cfc8d43ad624acabe2263da9f8ba6b4
Autor:
Sandra Marcia Muxel, Marco Antonio Pires-Lapa, Alex Willian Arantes Monteiro, Erika Cecon, Eduardo Koji Tamura, Lucile Maria Floeter-Winter, Regina P Markus
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52010 (2012)
We demonstrate that during inflammatory responses the nuclear factor kappa B (NF-κB) induces the synthesis of melatonin by macrophages and that macrophage-synthesized melatonin modulates the function of these professional phagocytes in an autocrine
Externí odkaz:
https://doaj.org/article/fb064403e9724f11b618fa5a100ca2e1
Autor:
Sanseray da Silveira Cruz-Machado, Luciana Pinato, Eduardo Koji Tamura, Cláudia Emanuele Carvalho-Sousa, Regina P Markus
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40142 (2012)
The pineal gland, a circumventricular organ, plays an integrative role in defense responses. The injury-induced suppression of the pineal gland hormone, melatonin, which is triggered by darkness, allows the mounting of innate immune responses. We hav
Externí odkaz:
https://doaj.org/article/c3cd5ab5613f42e09ecb5179681908be
Autor:
Henrique Roman-Ramos, Álvaro R. B. Prieto-da-Silva, Humberto Dellê, Rafael S. Floriano, Lourdes Dias, Stephen Hyslop, Raphael Schezaro-Ramos, Denis Servent, Gilles Mourier, Jéssica Lopes de Oliveira, Douglas Edgard Lemes, Letícia V. Costa-Lotufo, Jane S. Oliveira, Milene Cristina Menezes, Regina P. Markus, Paulo Lee Ho
Publikováno v:
Toxins, Vol 16, Iss 4, p 164 (2024)
Coralsnakes (Micrurus spp.) are the only elapids found throughout the Americas. They are recognized for their highly neurotoxic venom, which is comprised of a wide variety of toxins, including the stable, low-mass toxins known as three-finger toxins
Externí odkaz:
https://doaj.org/article/fd3e0d560549473e91b837667bb67b21
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Daily rhythm of melatonin synchronizes the body to the light/dark environmental cycle. Several hypotheses have been raised to understand the intersections between melatonin and depression, in which changes in rest-activity and sleep patterns are prom
Externí odkaz:
https://doaj.org/article/5946f1ec7c024486a5bbd47e4d75feb5
Autor:
Marlina O. Córdoba‐Moreno, Mariana Trivilin Mendes, Regina P. Markus, Pedro Augusto Fernandes
Publikováno v:
The Journal of Physiology. 601:535-549
Chronic inflammatory diseases are triggered by causal stimuli that might occur long before the appearance of the symptoms. Increasing evidence suggests that these stimuli are necessary but not always sufficient to induce the diseases. The murine mode
Autor:
Regina P Markus, Kassiano DS Sousa, Sandra M Muxel, Waldir Caldeira, Isabela L Trevisan, Marlina Córdoba-Moreno, Edson ED Ribeiro-Paz, Adriessa A Santos, Ewerton S Souza
Publikováno v:
Melatonin Research. 5:55-67
Microglia, the sentinels of the central nervous system, are responsible for the surveillance and the innate defense against pathogen or danger/damage-associated molecular patterns. The response is fine-tuned to restrain pro-inflammatory responses, pr
Autor:
Leonardo Vinícius Monteiro de Assis, Gabriela Sarti Kinker, Maria Nathália Moraes, Regina P. Markus, Pedro Augusto Fernandes, Ana Maria de Lauro Castrucci
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
IntroductionMelanoma is the most lethal type of skin cancer, with increasing incidence and mortality rates worldwide. Multiple studies have demonstrated a link between cancer development/progression and circadian disruption; however, the complex role
Externí odkaz:
https://doaj.org/article/db40ac09ab8f4949888763b94dd11130