In Vivo Efficacy of Artesunate/Sulphadoxine-Pyrimethamine versus Artesunate/Amodiaquine in the Treatment of Uncomplicated P. falciparium Malaria in Children around the Slope of Mount Cameroon: A Randomized Controlled Trial

Autor: Tobias O. Apinjoh, Judith K. Anchang-Kimbi, Marcelus U. Ajonina, Esther T. Njonguo, Clarisse Njua-Yafi, Andre N. Ngwai, Regina N. Mugri, Eric A. Achidi

Publikováno v: Biomedicines, Vol 4, Iss 1, p 5 (2016)

Background: The development and spread of antimalarial drug resistant parasites contributes to the global impact of the disease. In vivo efficacy assessments of treatments for Plasmodium falciparum malaria are essential for ensuring effective case ma

Externí odkaz: https://doaj.org/article/e73fc209cdbf440685191e2c5f467a5d

Reappraisal of known malaria resistance loci in a large multicenter study

Autor: Malcolm E. Molyneux, Peter Siba, Andre Ndi, Valentina D. Mangano, Cao Quang Thai, Vysaul Nyirongo, Subulade A. Olaniyan, Angie Green, Mahamadou A. Thera, Timothy M. E. Davis, Síle F. Molloy, Kathryn Fitzpatrick, Giorgio Sirugo, Edith C. Bougouma, Chris Drakeley, Anthony Enimil, Angela Allen, Olukemi K. Amodu, Christina Hubbart, Nuno Sepúlveda, Nguyen Hoan Phu, M Jallow, Carolyne M. Ndila, Stanley Usen, Kimberly J. Johnson, Hugh Reyburn, Taane G. Clark, Dominic P. Kwiatkowski, Si Quang Le, Tobias O. Apinjoh, Kalifa Bojang, Jennifer R Evans, Michael D. Wilson, Lee Hart, Sophie Uyoga, Angeliki Kerasidou, Eric A. Achidi, Steve Allen, Kirk A. Rockett, Pascal Michon, Ivo Mueller, Anna E. Jeffreys, Belco Poudiougou, Anita Ghansah, Norbert Peshu, Fatoumatta Sisay-Joof, David Kachala, Sodiomon B. Sirima, David J. Conway, Geraldine M. Clarke, Regina N. Mugri, Moses Laman, Aaron Vanderwal, Miguel A. Sanjoaquin, Sibiry Sissoko, Ousmane Touré, Laurens Manning, Chris C. A. Spencer, Matti Pirinen, David Modiano, Sarah J. Dunstan, Harin Karunajeewa, Alexander Macharia, Tran Tinh Hien, Tsiri Agbenyega, Gavin Band, Kate Rowlands, Salimata Konate, Rachel Craik, L. Amenga-Etego, Nguyen Ngoc Quyen, Kwadwo A. Koram, Amadou Niangaly, Margaret Pinder, Alphaxard Manjurano, Terrie E. Taylor, Ogobara K. Doumbo, Eleanor M. Riley, Jeremy Farrar, Victoria Cornelius, Kevin Marsh, Thomas N. Williams

Publikováno v: Nature genetics

Many human genetic associations with resistance to malaria have been reported, but few have been reliably replicated. We collected data on 11,890 cases of severe malaria due to Plasmodium falciparum and 17,441 controls from 12 locations in Africa, As

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717b83ca63cd08f7da9dda709ed341e2
https://doi.org/10.1038/ng.3107

Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case-control study

Autor: Dominic P. Kwiatkowski, Taane G. Clark, Eric A. Achidi, Kirk A. Rockett, Judith K. Anchang-Kimbi, Regina N. Mugri, Clarisse Njua-Yafi, Andre N Ngwai, Tobias O. Apinjoh

Publikováno v: Malaria Journal

Background: Plasmodium falciparum malaria is one of the most widespread and deadliest infectious diseases in children under five years in endemic areas. The disease has been a strong force for evolutionary selection in the human genome, and uncoverin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6761e914de61a4b0cad589807b493dd8
https://doi.org/10.1186/1475-2875-13-236

In Vivo Efficacy of Artesunate/Sulphadoxine-Pyrimethamine versus Artesunate/Amodiaquine in the Treatment of Uncomplicated P. falciparium Malaria in Children around the Slope of Mount Cameroon: A Randomized Controlled Trial

Autor: Clarisse Njua-Yafi, Marcelus U. Ajonina, Tobias O. Apinjoh, Eric A. Achidi, Regina N. Mugri, Andre N Ngwai, Esther T Njonguo, Judith K. Anchang-Kimbi

Publikováno v: Biomedicines
Biomedicines; Volume 4; Issue 1; Pages: 5
Biomedicines, Vol 4, Iss 1, p 5 (2016)

Background: The development and spread of antimalarial drug resistant parasites contributes to the global impact of the disease. In vivo efficacy assessments of treatments for Plasmodium falciparum malaria are essential for ensuring effective case ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42e6db1a22a1ea9fb9a280dbb941786
http://europepmc.org/articles/PMC5344242

Determinants of Infant Susceptibility to Malaria During the First Year of Life in South Western Cameroon

Autor: Delphine A. Tangoh, Regina N. Mugri, Beatrice T. Loh, Eric A. Achidi, Rolland B. Tata, Clarisse Njua-Yafi, Hanesh F. Chi, Tobias O. Apinjoh, Judith K. Anchang-Kimbi

Publikováno v: Open Forum Infectious Diseases

Background. Falciparum malaria is an important pediatric infectious disease that frequently affects pregnant women and alters infant morbidity. However, the impact of some prenatal and perinatal risk factors such as season and intermittent preventive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c41801170b6201dcc24e27938c60b7
https://doi.org/10.1093/ofid/ofv012