Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Regina Mahr"'
Autor:
Angela Kranz, Tino Polen, Christian Kotulla, Annette Arndt, Graziella Bosco, Michael Bussmann, Ava Chattopadhyay, Annette Cramer, Cedric-Farhad Davoudi, Ursula Degner, Ramon Diesveld, Raphael Freiherr von Boeselager, Kim Gärtner, Cornelia Gätgens, Tobias Georgi, Christian Geraths, Sabine Haas, Antonia Heyer, Max Hünnefeld, Takeru Ishige, Armin Kabus, Nicolai Kallscheuer, Larissa Kever, Simon Klaffl, Britta Kleine, Martina Kočan, Abigail Koch-Koerfges, Kim J. Kraxner, Andreas Krug, Aileen Krüger, Andreas Küberl, Mohamed Labib, Christian Lange, Christina Mack, Tomoya Maeda, Regina Mahr, Stephan Majda, Andrea Michel, Xenia Morosov, Olga Müller, Arun M. Nanda, Jens Nickel, Jennifer Pahlke, Eugen Pfeifer, Laura Platzen, Paul Ramp, Doris Rittmann, Steffen Schaffer, Sandra Scheele, Stephanie Spelberg, Julia Schulte, Jens-Eric Schweitzer, Georg Sindelar, Ulrike Sorger-Herrmann, Markus Spelberg, Corinna Stansen, Apilaasha Tharmasothirajan, Jan van Ooyen, Philana van Summeren-Wesenhagen, Michael Vogt, Sabrina Witthoff, Lingfeng Zhu, Bernhard J. Eikmanns, Marco Oldiges, Georg Schaumann, Meike Baumgart, Melanie Brocker, Lothar Eggeling, Roland Freudl, Julia Frunzke, Jan Marienhagen, Volker F. Wendisch, Michael Bott
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-10 (2022)
Abstract Corynebacterium glutamicum is the major host for the industrial production of amino acids and has become one of the best studied model organisms in microbial biotechnology. Rational strain construction has led to an improvement of producer s
Externí odkaz:
https://doaj.org/article/40c95f8ff8694597bb7bae3c633c682c
Autor:
Nurije Mustafi, Alexander Grünberger, Regina Mahr, Stefan Helfrich, Katharina Nöh, Bastian Blombach, Dietrich Kohlheyer, Julia Frunzke
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85731 (2014)
The majority of biotechnologically relevant metabolites do not impart a conspicuous phenotype to the producing cell. Consequently, the analysis of microbial metabolite production is still dominated by bulk techniques, which may obscure significant va
Externí odkaz:
https://doaj.org/article/7e9d3bcb43b645fcb68625714f4371f2
The pyruvate dehydrogenase complex (PDHC) catalyzes the oxidative decarboxylation of pyruvate, yielding acetyl coenzyme A (acetyl-CoA) and CO(2). The PDHC-deficient Corynebacterium glutamicum ΔaceE strain therefore lacks an important decarboxylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ac7e06ec2cf0337e60748f1cd1c7cc
https://europepmc.org/articles/PMC6755737/
https://europepmc.org/articles/PMC6755737/
Autor:
Volker F. Wendisch, Dietrich Kohlheyer, Anita Loeschcke, Julia Frunzke, Jörg Pietruszka, Claus Bier, Petra Peters-Wendisch, Thomas Drepper, Jonas Frohwitter, Regina Mahr, Dennis Binder, Alexander Grünberger, Karl-Erich Jaeger
Publikováno v:
Applied and Environmental Microbiology. 82:6141-6149
Precise control of microbial gene expression resulting in a defined, fast, and homogeneous response is of utmost importance for synthetic bio(techno)logical applications. However, even broadly applied biotechnological workhorses, such as Corynebacter
Autor:
Michael Bott, Tita Aryani, Regina Mahr, Julia Schulte, Michael H. Limberg, Wolfgang Wiechert, Meike Baumgart, Marco Oldiges
Publikováno v:
Biotechnology and Bioengineering. 114:560-575
Performance losses during scale-up are described since decades, but are still one of the major obstacles for industrial bioprocess development. Consequently, robustness to inhomogeneous cultivation environments is an important quality of industrial p
The pyruvate dehydrogenase complex (PDHC) catalyzes the oxidative decarboxylation of pyruvate yielding acetyl-CoA and CO2. The PDHC-deficientCorynebacterium glutamicumstrain ΔaceEis therefore lacking an important decarboxylation step in central meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa22136bd5d52f616dd514276f67e91
Publikováno v:
Applied Microbiology and Biotechnology. 100:6739-6753
In recent years, the application of transcription factor-based biosensors for the engineering of microbial production strains opened up new opportunities for industrial biotechnology. However, the design of synthetic regulatory circuits depends on th
Autor:
Dennis, Binder, Jonas, Frohwitter, Regina, Mahr, Claus, Bier, Alexander, Grünberger, Anita, Loeschcke, Petra, Peters-Wendisch, Dietrich, Kohlheyer, Jörg, Pietruszka, Julia, Frunzke, Karl-Erich, Jaeger, Volker F, Wendisch, Thomas, Drepper
Publikováno v:
Applied and environmental microbiology. 82(20)
Precise control of microbial gene expression resulting in a defined, fast, and homogeneous response is of utmost importance for synthetic bio(techno)logical applications. However, even broadly applied biotechnological workhorses, such as Corynebacter
Autor:
Mirko Hekman, Lisa Polzien, Thomas Müller, Inge Schwarzenau, Regina Mahr, Ulf R. Rapp, Angela Baljuls
Publikováno v:
Journal of Biological Chemistry. 286:16491-16503
The serine/threonine kinase RAF is a central component of the MAPK cascade. Regulation of RAF activity is highly complex and involves recruitment to membranes and association with Ras and scaffold proteins as well as multiple phosphorylation and deph
Autor:
Julia Frunzke, Regina Mahr
Publikováno v:
BIOspektrum. 19:739-741
Microbes have evolved a variety of sensor devices for the intracellular detection of small molecules. This capability was recently harnessed for the construction of transcription factor-based biosensors translating the intracellular amino acid accumu