Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Regina M Graham"'
Autor:
John W Thompson, Jianqin Wei, Kweku Appau, Huilan Wang, Hong Yu, Maria G Spiga, Regina M Graham, Keith A Webster
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136847 (2015)
Bnip3 is a hypoxia-regulated member of the Bcl-2 family of proteins that is implicated in apoptosis, programmed necrosis, autophagy and mitophagy. Mitochondria are thought to be the primary targets of Bnip3 although its activities may extend to the E
Externí odkaz:
https://doaj.org/article/89334a3f740f49aebdaaf24656a378cd
Autor:
Frederic A. Vallejo, Anthony Sanchez, Branko Cuglievan, Winston M. Walters, Guillermo De Angulo, Steven Vanni, Regina M. Graham
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
High-risk neuroblastoma (NB) portends very poor prognoses in children. Targeting tumor metabolism has emerged as a novel therapeutic strategy. High levels of nicotinamide-adenine-dinucleotide (NAD+) are required for rapid cell proliferation. Nicotina
Externí odkaz:
https://doaj.org/article/708da4feb36e4c00b359be5e663ee0ec
Publikováno v:
ACS Omega, Vol 4, Iss 27, Pp 22280-22291 (2019)
Externí odkaz:
https://doaj.org/article/a52671f582ee4638b746825d7a2adbf7
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glioblastoma (GBM) remains one of the most lethal primary brain tumors in both adult and pediatric patients. Targeting tumor metabolism has emerged as a promising-targeted therapeutic strategy for GBM and characteristically resistant GBM stem-like ce
Externí odkaz:
https://doaj.org/article/676d75353b59421fa4516e810200a505
Autor:
Eduardo A. Veliz, Anastasiia Kaplina, Sajini D. Hettiarachchi, Athina L. Yoham, Carolina Matta, Sabrin Safar, Meghana Sankaran, Esther L. Abadi, Emel Kirbas Cilingir, Frederic A. Vallejo, Winston M. Walters, Steven Vanni, Roger M. Leblanc, Regina M. Graham
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1465 (2022)
The current prognosis for glioblastoma is dismal. Treatment-resistant glioblastoma stem cells (GSCs) and the failure of most drugs to reach therapeutic levels within the tumor remain formidable obstacles to successful treatment. Chalcones are aromati
Externí odkaz:
https://doaj.org/article/e8985b1057ce471ca50d4e7b774a1aad
Autor:
Vasileios Stathias, Anna M. Jermakowicz, Marie E. Maloof, Michele Forlin, Winston Walters, Robert K. Suter, Michael A. Durante, Sion L. Williams, J. William Harbour, Claude-Henry Volmar, Nicholas J. Lyons, Claes Wahlestedt, Regina M. Graham, Michael E. Ivan, Ricardo J. Komotar, Jann N. Sarkaria, Aravind Subramanian, Todd R. Golub, Stephan C. Schürer, Nagi G. Ayad
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Inherent or acquired resistance to treatment of glioblastoma (GBM) is nearly universal. Here, the authors introduce a platform to identify synergistic drug combinations for patient-specific treatment of GBM based on gene expression signatures and sma
Externí odkaz:
https://doaj.org/article/27c294a5f7c843d6a3a8dc34a08977c6
Autor:
Yiqun Zhou, Jiuyan Chen, Emel Kirbas Cilingir, Wei Zhang, Lemay Gonzalez, Samuel Perez, Arjuna Davila, Nicholas Brejcha, Jun Gu, Wenquan Shi, Justin B. Domena, Braulio C. L. B. Ferreira, Fuwu Zhang, Frederic A. Vallejo, Daniela Toledo, Piumi Y. Liyanage, Regina M. Graham, Julia Dallman, Zhili Peng, Christian Agatemor, Alessandro Catenazzi, Roger M. Leblanc
Publikováno v:
Nanoscale. 14:17607-17624
The carbon nitride dot (CND) is an emerging carbon-based nanomaterial. It possesses rich surface functional moieties and a carbon nitride core. Spectroscopic data have demonstrated the analogy between CNDs and cytosine/uracil. Recently, it was found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05df5858942d4f70577f2d41a71c7d7
https://doi.org/10.1039/d2nr04778k
https://doi.org/10.1039/d2nr04778k
Autor:
Elif S. Seven, Emel Kirbas Cilingir, Mattia Bartoli, Yiqun Zhou, Rachel Sampson, Wenquan Shi, Zhili Peng, Raja Ram Pandey, Charles C. Chusuei, Alberto Tagliaferro, Steven Vanni, Regina M. Graham, Yasin B. Seven, Roger M. Leblanc
Publikováno v:
Journal of colloid and interface science. 630
Carbon dots (CDs) from glucose were synthesized using two of the most common bottom-up methods, namely, microwave assisted (MW) and hydrothermal carbonization (HT). Synthetic parameters such as reaction time, temperature, and precursor concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9865e12b6bd4fe63120de74e9c7c10ad
https://pubmed.ncbi.nlm.nih.gov/36244103
https://pubmed.ncbi.nlm.nih.gov/36244103
Autor:
Emel Kirbas Cilingir, Meghana Sankaran, Jordan M. Garber, Frederic Anthony Vallejo, Mattia Bartoli, Alberto Tagliaferro, Steven Vanni, Regina M. Graham, Roger M. Leblanc
Publikováno v:
Nanoscale. 14(27)
Carbon Dots (CDs) have recently attracted a considerable amount of attention thanks to their well-documented biocompatibility, tunable photoluminescence, and excellent water solubility. However, CDs need further analysis before their potential use in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8698cd8eaa6592725fddfc2e455faf0a
https://pubmed.ncbi.nlm.nih.gov/35766148
https://pubmed.ncbi.nlm.nih.gov/35766148
Autor:
Emel Kirbas Cilingir, Sajini D. Hettiarachchi, Yiqun Zhou, Braulio CLB Ferreira, Steven Vanni, Roger M. Leblanc, Regina M. Graham
Ultimate goal of the nanomedicine is built on the idea of robust targeted delivery of complex assemblies that contain sufficient amount of multiple therapeutics and diagnostic agents for highly localized payload release with no adverse side effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f83ea21c90cb298edd7faef9653a95c0
https://doi.org/10.21203/rs.3.rs-1712584/v1
https://doi.org/10.21203/rs.3.rs-1712584/v1
