Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Regina Le Roux"'
Autor:
Ashmeetha Manilall, Lebogang Mokotedi, Sulè Gunter, Regina Le Roux, Serena Fourie, Colleen A. Flanagan, Aletta M. E. Millen
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Titin phosphorylation contributes to left ventricular (LV) diastolic dysfunction. The independent effects of inflammation on the molecular pathways that regulate titin phosphorylation are unclear. Methods We investigated the effec
Externí odkaz:
https://doaj.org/article/73f4db01916a4900874dfedfb2989ff8
Autor:
Sulè Gunter, Frederic S Michel, Serena S Fourie, Mikayra Singh, Regina le Roux, Ashmeetha Manilall, Lebogang P Mokotedi, Aletta M E Millen
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0264558 (2022)
Chronic inflammation causes dysregulated expression of microRNAs. Aberrant microRNA expression is associated with endothelial dysfunction. In this study we determined whether TNF-α inhibition impacted the expression of miRNA-146a-5p and miRNA-155-5p
Externí odkaz:
https://doaj.org/article/38944472a26848d9bfac0d26f732980a
Autor:
Ashmeetha Manilall, Lebogang Mokotedi, Sulè Gunter, Regina Le Roux, Serena Fourie, Colleen A. Flanagan, Aletta M.E. Millen
Publikováno v:
Physiological Reports, Vol 9, Iss 21, Pp n/a-n/a (2021)
Abstract Objective To determine the mechanisms of inflammation‐induced left ventricular (LV) remodeling and effects of blocking circulating tumor necrosis factor alpha (TNF‐α) in a model of systemic inflammation. Methods Seventy Sprague‐Dawley
Externí odkaz:
https://doaj.org/article/084981e9d39d49d897adb0c6dd483b61
Autor:
Ashmeetha Manilall, Lebogang Mokotedi, Sulè Gunter, Regina Le Roux, Serena Fourie, Colleen A Flanagan, Aletta ME Millen
Publikováno v:
Journal of Cardiovascular Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::369fff37237421da6f24c5c98a736876
https://doi.org/10.1097/fjc.0000000000001428
https://doi.org/10.1097/fjc.0000000000001428
Autor:
Lebogang Mokotedi, Aletta M.E. Millen, Tshimangadzo M. Denga, Sulè Gunter, Serena Fourie, Regina le Roux, Ashmeetha Manilall
Publikováno v:
Endocrine, metabolicimmune disorders drug targets.
Background: Interleukin-6 (IL-6) receptor blockers improve systemic inflammation, however, their inconsistent effects on lipid metabolism and drug-induced liver injuries warrant further investigation. This study aimed to determine the effects of IL-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ac861af25bd249d83cc0267ad3b81f
https://pubmed.ncbi.nlm.nih.gov/36263484
https://pubmed.ncbi.nlm.nih.gov/36263484
Autor:
Sule Gunter, Lebogang Mokotedi, Serena Fourie, Ashmeetha Manilall, Colleen A. Flanagan, Regina Le Roux, Aletta M.E. Millen
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 21, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 21, Pp n/a-n/a (2021)
Objective To determine the mechanisms of inflammation‐induced left ventricular (LV) remodeling and effects of blocking circulating tumor necrosis factor alpha (TNF‐α) in a model of systemic inflammation. Methods Seventy Sprague‐Dawley rats wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fee0874d184d8952f52998d129e265
http://europepmc.org/articles/PMC8554769
http://europepmc.org/articles/PMC8554769
Autor:
Sulè Gunter, Frederic S. Michel, Serena S. Fourie, Mikayra Singh, Regina le Roux, Ashmeetha Manilall, Lebogang P. Mokotedi, Aletta M. E. Millen
Publikováno v:
PloS one. 17(2)
Chronic inflammation causes dysregulated expression of microRNAs. Aberrant microRNA expression is associated with endothelial dysfunction. In this study we determined whether TNF-α inhibition impacted the expression of miRNA-146a-5p and miRNA-155-5p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b25696c5c591baa34cc3b7286adf4a1
https://pubmed.ncbi.nlm.nih.gov/35213638
https://pubmed.ncbi.nlm.nih.gov/35213638