Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Regina Kascsak"'
Autor:
Fernando Goñi, Frances Prelli, Yong Ji, Henrieta Scholtzova, Jing Yang, Yanjie Sun, Feng-Xia Liang, Regina Kascsak, Richard Kascsak, Pankaj Mehta, Thomas Wisniewski
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13391 (2010)
Many neurodegenerative diseases are characterized by the conformational change of normal self-proteins into amyloidogenic, pathological conformers, which share structural properties such as high β-sheet content and resistance to degradation. The mos
Externí odkaz:
https://doaj.org/article/57529258aef14c2d86d9ebfc40e20fbd
Autor:
Thomas Wisniewski, Tatyana Adayev, Wojciech Kaczmarski, Verónica Martínez-Cerdeño, Giuseppe La Fauci, Jerzy Wegiel, Jarek Wegiel, Richard J. Kascsak, W. Ted Brown, Krzysztof Nowicki, Regina Kascsak, Michael Flory, Izabela Kuchna
Publikováno v:
Autism Research. 11:1316-1331
Fragile X syndrome (FXS), caused by lack of fragile X mental retardation protein (FMRP), is associated with a high prevalence of autism. The deficit of FMRP reported in idiopathic autism suggests a mechanistic overlap between FXS and autism. The over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a6b57ac1bc9b25d5f51c6edfd4a298e
https://doi.org/10.1002/aur.2003
https://doi.org/10.1002/aur.2003
Autor:
Sandrine Sanchez, Martin J. Sadowski, Regina Kascsak, Joanna Pankiewicz, Richard J. Kascsak, Kent Kirshenbaum
PrP(Sc) is an infectious and disease specific conformer of the prion protein, which accumulation in the CNS underlies the pathology of prion diseases. PrP(Sc) replicates by binding to the cellular conformer of the prion protein (PrP(C)) expressed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc0e272b0534018227baf0cc460fab9
https://europepmc.org/articles/PMC6326903/
https://europepmc.org/articles/PMC6326903/
Autor:
Jarek, Wegiel, W Ted, Brown, Giuseppe, La Fauci, Tatyana, Adayev, Richard, Kascsak, Regina, Kascsak, Michael, Flory, Wojciech, Kaczmarski, Izabela, Kuchna, Krzysztof, Nowicki, Veronica, Martinez-Cerdeno, Thomas, Wisniewski, Jerzy, Wegiel
Publikováno v:
Autism research : official journal of the International Society for Autism Research. 11(10)
Fragile X syndrome (FXS), caused by lack of fragile X mental retardation protein (FMRP), is associated with a high prevalence of autism. The deficit of FMRP reported in idiopathic autism suggests a mechanistic overlap between FXS and autism. The over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4adcf8c11837ef4803c4f5b58e3c69cd
https://pubmed.ncbi.nlm.nih.gov/30107092
https://pubmed.ncbi.nlm.nih.gov/30107092
Autor:
Richard J. Kascsak, Regina Kascsak, Martin J. Sadowski, Kent Kirshenbaum, Sandrine Sanchez, Joanna Pankiewicz
Publikováno v:
Alzheimer's & Dementia. 15:P1001-P1002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e8a5e86d16ae0e1a73d04a90aaa15a7
https://doi.org/10.1016/j.jalz.2019.06.3216
https://doi.org/10.1016/j.jalz.2019.06.3216
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b331b562c4887a1bf3a524f24c4eac95
https://doi.org/10.1016/j.jalz.2017.06.054
https://doi.org/10.1016/j.jalz.2017.06.054
Autor:
Richard J. Kascsak, Regina Kascsak, Daryl S. Spinner, Thomas Wisniewski, Joanna Pankiewicz, Henrieta Scholtzova, Martin J. Sadowski, Frances Prelli
Publikováno v:
Neurobiology of Disease, Vol 34, Iss 2, Pp 267-278 (2009)
The pathogenesis of prion diseases is related to conformational transformation of cellular prion protein (PrP(C)) into a toxic, infectious, and self-replicating conformer termed PrP(Sc). Following extracerebral inoculation, the replication of PrP(Sc)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3876f2b3325c63636c1a013b3061c493
https://doi.org/10.1016/j.nbd.2009.01.013
https://doi.org/10.1016/j.nbd.2009.01.013
Autor:
Jae I. I. Kim, William R. Levis, Xuemin Ye, Daryl S. Spinner, Georgia Schuller-Levis, Richard J. Kascsak, Thomas Wisniewski, Michael Flory, Giuseppe LaFauci, Richard I. Carp, Harry C. Meeker, Regina Kascsak
Publikováno v:
Journal of Leukocyte Biology. 81:1374-1385
Prion diseases are characterized by conversion of the cellular prion protein (PrP C )t o a protease-resistant conformer, the srapie form of PrP (PrP Sc ). Humoral immune responses to non- denatured forms of PrP Sc have never been fully characterized.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4f8f15558e042850cbad4f66cfb896
https://doi.org/10.1189/jlb.1106665
https://doi.org/10.1189/jlb.1106665
Autor:
Harry C. Meeker, Thomas Wisniewski, Daryl S. Spinner, Man Sun Sy, Marcin Sadowski, Regina Kascsak, Frances Prelli, Richard J. Kascsak, Richard I. Carp, Joanna Pankiewicz
Publikováno v:
European Journal of Neuroscience. 23:2635-2647
Prion diseases are transmissible and invariably fatal neurodegenerative disorders associated with a conformational transformation of the cellular prion protein (PrPC) into a self-replicating and proteinase K (PK)-resistant conformer, scrapie PrP (PrP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90887a13494ecb65968a8b138916790e
https://doi.org/10.1111/j.1460-9568.2006.04805.x
https://doi.org/10.1111/j.1460-9568.2006.04805.x
Autor:
Richard I. Carp, Richard J. Kascsak, Blas Frangione, Man Sun Sy, Henrieta Scholtzova, Regina Kascsak, Einar M. Sigurdsson, Harry C. Meeker, Thomas Wisniewski, Ruliang Li
Publikováno v:
Neuroscience Letters. 336:185-187
Prion disease is characterized by a conformational change of the normal form of the prion protein (PrP C ) to the scrapie-associated form (PrP Sc ). Since the emergence of new variant Creutzfeldt-Jakob disease a potentially large human population is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a098e3c411e235dc6818002f2edb843
https://doi.org/10.1016/s0304-3940(02)01192-8
https://doi.org/10.1016/s0304-3940(02)01192-8