Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Regina Hoo"'
Autor:
Anthony Siau, Jing Wen Ang, Omar Sheriff, Regina Hoo, Han Ping Loh, Donald Tay, Ximei Huang, Xue Yan Yam, Soak Kuan Lai, Wei Meng, Irene Julca, Sze Siu Kwan, Marek Mutwil, Peter R. Preiser
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113419- (2023)
Summary: Plasmodium parasites contribute to one of the highest global infectious disease burdens. To achieve this success, the parasite has evolved a range of specialized subcellular compartments to extensively remodel the host cell for its survival.
Externí odkaz:
https://doaj.org/article/f755b27c4ab44c779d3fb613f336e463
Autor:
Marvin Chew, Weijian Ye, Radoslaw Igor Omelianczyk, Charisse Flerida Pasaje, Regina Hoo, Qingfeng Chen, Jacquin C. Niles, Jianzhu Chen, Peter Preiser
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
During the erythrocyte (RBC) stage of P. falciparum infection variant surface antigens (VSAs) such as PfEMP1s and RIFINs expressed on RBCs are important for infection and evasion of host innate immune system. Here, Chew et al. use a NSG mouse model,
Externí odkaz:
https://doaj.org/article/9ff80ee8ef3d4393a5e27c06c8575028
Autor:
Regina Hoo, Ellen Bruske, Sandra Dimonte, Lei Zhu, Benjamin Mordmüller, B. Kim Lee Sim, Peter G. Kremsner, Stephen L. Hoffman, Zbynek Bozdech, Matthias Frank, Peter R. Preiser
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 442-452 (2019)
Background: The transcriptome of Plasmodium falciparum clinical isolates varies according to strain, mosquito bites, disease severity and clinical history. Therefore, it remains a challenge to directly interpret the parasite's transcriptomic informat
Externí odkaz:
https://doaj.org/article/1630dd54f6a5412db0d24a84756d3ca4
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
During pregnancy, the placenta forms the anatomical barrier between the mother and developing fetus. Infectious agents can potentially breach the placental barrier resulting in pathogenic transmission from mother to fetus. Innate immune responses, or
Externí odkaz:
https://doaj.org/article/11602734e2dd40c19917c9293faab069
Autor:
Regina Hoo, Lei Zhu, Anburaj Amaladoss, Sachel Mok, Onguma Natalang, Stacey A. Lapp, Guangan Hu, Kingsley Liew, Mary R. Galinski, Zbynek Bozdech, Peter R. Preiser
Publikováno v:
EBioMedicine, Vol 7, Iss C, Pp 255-266 (2016)
The genome sequence available for different Plasmodium species is a valuable resource for understanding malaria parasite biology. However, comparative genomics on its own cannot fully explain all the species-specific differences which suggests that o
Externí odkaz:
https://doaj.org/article/9c858bda6e8742c98a19aa3cf7a84a41
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115243 (2014)
Polysaccharide (PS) capsules are important virulence determinants for many bacterial pathogens. Bordetella pertussis, the agent of whooping cough, produces a surface associated microcapsule but its role in pertussis pathogenesis remained unknown. Her
Externí odkaz:
https://doaj.org/article/b211229f5415488f9c7c6715c09b7950
Autor:
Chuan Xu, Martin Prete, Simone Webb, Laura Jardine, Benjamin Stewart, Regina Hoo, Peng He, Sarah A. Teichmann
SummaryHarmonizing cell types with respect to transcriptomics identity and nomenclature across the single-cell community and assembling them into a common framework is an essential step towards building a standardized Human Cell Atlas. Here we presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e1c950622f9c8214e04b99ced11fce9
https://doi.org/10.1101/2023.05.01.538994
https://doi.org/10.1101/2023.05.01.538994
Autor:
Regina Hoo, Elias R. Ruiz-Morales, Iva Kelava, Carmen Sancho-Serra, Cecilia Icoresi Mazzeo, Sara Chelaghma, Elizabeth Tuck, Alexander V. Predeus, David Fernandez-Antoran, Ross F. Waller, Marcus Lee, Roser Vento-Tormo
Placental infections are a major worldwide burden, particularly in developing countries. The placenta is a transient tissue located at the interface between the mother and the fetus. Some pathogens can access the placental barrier resulting in pathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::823dc83e9800f2e9a8fc7d71f3fc3bae
https://doi.org/10.1101/2023.01.02.522155
https://doi.org/10.1101/2023.01.02.522155
Autor:
Elena Prigmore, Louis-François Handfield, Michael R. Stratton, Tong Li, Mercedes Jimenez-Linan, Lucy Gardner, Luz Garcia-Alonso, Tarryn Porter, Krishnaa T. Mahbubani, Vitalii Kleshchevnikov, Anna Arutyunyan, Hassan Massalha, Monika Dabrowska, Paul Ayuk, Kwasi Kwakwa, Ashley Moffett, Benjamin Woodhams, Kourosh Saeb-Parsy, Ridma C. Fernando, Regina Hoo, Elizabeth Tuck, Konstantina Nikolakopoulou, Stijn van Dongen, Valentina Lorenzi, Jong-Eun Park, Kenny Roberts, Cecilia Icoresi Mazzeo, Margherita Y. Turco, Vasyl Vaskivskyi, Martin Prete, Aleksandra Tarkowska, Roser Vento-Tormo, Krzysztof Polanski, Carmen Sancho-Serra, Cecilia Lindskog, Omer Ali Bayraktar, Vladimir Yu. Kiselev, Sarah A. Teichmann, Lia S. Campos, Luiza Moore
Publikováno v:
Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro
The endometrium, the mucosal lining of the uterus, undergoes dynamic changes throughout the menstrual cycle in response to ovarian hormones. We have generated dense single-cell and spatial reference maps of the human uterus and three-dimensional endo
Autor:
Javier Rodríguez-Ubreva, Louis-Francois Handfield, Baerbel Keller, Laura Ciudad, Carlos de la Calle-Fabregat, Gerard Godoy-Tena, Josep Calafell-Segura, Eduardo Andrés-León, Regina Hoo, Tarryn Porter, Elena Prigmore, Maike Hofmann, Annegrit Decker, Javier Martín, Klaus Warnatz, Roser Vento-Tormo, Esteban Ballestar
Patients with common variable immunodeficiency (CVID), the most prevalent symptomatic primary immunodeficiency, are characterized by hypogammaglobulinemia, poorly protective vaccine titers and increased susceptibility to infections. New pathogens suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307c107f51fed2756585410eb06bca86
http://hdl.handle.net/10261/307726
http://hdl.handle.net/10261/307726