Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Regina Goerse"'
Publikováno v:
Anti-Cancer Drugs. 22:253-261
Soy isoflavone genistein, a tyrosine kinase inhibitor and agonist of estrogen receptor-β (ERβ), is known to have antitumoral properties. Given that ERβ often is coexpressed with HER2 in breast cancer, both functions of genistein might be able to e
Autor:
Claus Lattrich, Maciej Skrzypczak, Anette Springwald, Oliver Treeck, Olaf Ortmann, Regina Goerse
Publikováno v:
Cancer Investigation. 28:904-909
Human gene icb-1 (C1orf38) has been initially cloned by our group from endometrial adenocarcinoma cells. In this study, we examined icb-1 expression in 90 endometrial cancer and normal endometrial tissue specimens. Expression of icb-1 was significant
Autor:
Anna Konwisorz, Regina Goerse, Oliver Treeck, Martina Haselberger, Anette Springwald, Olaf Ortmann
Publikováno v:
Endocrine-Related Cancer. 17:147-157
ICB-1 chromosome 1 open reading frame 38 (C1orf38) is a human gene initially described by our group to be involved in differentiation processes of cancer cells. Recently, we have reported ICB-1 as a novel estrogen target gene and identified an estrog
Autor:
Gitte Wenzel, Olaf Ortmann, Oliver Treeck, Arndt Hartmann, Regina Goerse, Gerd Schmitz, Georg Pfeiler
Publikováno v:
Maturitas. 63:253-256
Objective Adipositas and insulin resistance are modifiable risk factors for breast cancer. Adiponectin seems to be an important linkage of these associations. In this study, we investigated the relationship between intratumoral adiponectin receptor e
Autor:
Oliver Treeck, Ingolf Juhasz-Boess, Claus Lattrich, Regina Goerse, Felicitas Horn, Olaf Ortmann
Publikováno v:
Breast Cancer Research and Treatment. 110:507-520
Estrogen receptor beta gene codes for a variety of transcript isoforms resulting from alternative splicing, which are expressed both in mammary gland and in breast cancer cells. We studied the function of two exon-deleted ERbeta isoforms recently ide
Autor:
Regina Goerse, Claus Lattrich, Olaf Ortmann, Anette Springwald, Oliver Treeck, Anna Konwisorz, Martina Haselberger
Publikováno v:
International Journal of Molecular Medicine.
Icb-1 (C1orf38) is a human gene initially described by our group to be involved in differentiation processes of cancer cells. To further elucidate the function of the icb-1 gene in differentiation of breast and endometrial cancer cells, we knocked do
Autor:
Regina Goerse, Oliver Treeck, Claus Lattrich, Maciek Skrzypczak, Anette Springwald, Olaf Ortmann
Publikováno v:
Endocrine. 37(3)
The human progesterone receptor (PR) and estrogen receptor genes (ESR1 and ESR2) are known to code for a multitude of transcript variants resulting from alternative splicing. Many of them are translated into nuclear receptor proteins with altered str
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 118(1-2)
G-protein coupled receptor GPR30 has been demonstrated to mediate estrogenic effects on essential features of human breast cancer cells. Polymorphisms in GPR30 gene might therefore affect breast cancer susceptibility or tumor characteristics. This is
Autor:
Georg Pfeiler, Arndt Hartmann, Olaf Ortmann, Regina Goerse, Oliver Treeck, Gerd Schmitz, Gitte Wenzel
Publikováno v:
Senologie - Zeitschrift für Mammadiagnostik und -therapie. 5
Obesity increases breast cancer risk in post-menopausal women. This is, in part, due to elevated non-glandular aromatase activity, resulting in higher estradiol serum levels. We tested the hypothesis that obesity and menopausal status influence the i
Autor:
Oliver Treeck, Ingolf Juhasz-Boess, Claus Lattrich, Felicitas Horn, Regina Goerse, Olaf Ortmann
Publikováno v:
Breast Cancer Research & Treatment; Aug2008, Vol. 110 Issue 3, p507-520, 14p, 1 Chart, 5 Graphs