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pro vyhledávání: '"Regina Gilman-Politi"'
Autor:
Regina Gilman-Politi, Daniel Harries
Publikováno v:
Journal of Chemical Theory and Computation. 7:3816-3828
Many polyols and carbohydrates serve in different organisms as protective osmolytes that help to stabilize proteins in their native, functional state, even under a variety of environmental stresses. However, despite their important role, much of the
Publikováno v:
Faraday discussions. 160
Numerous cellular cosolutes significantly impact the way that proteins and other biomacromolecules act and interact. We have followed the thermodynamic effect of several cosolute classes, including polymers, cellular osmolytes, and inorganic salts, o
Publikováno v:
Biophysical Journal. 104:564a
On the molecular level, life is established through the specific interaction between and within macromolecules in an aqueous environment. It is increasingly realized, however, that even modest changes in solution conditions, brought on by the presenc